c Fos (FOS) pSer374 (incl. pos. control) Mouse Monoclonal Antibody [Clone ID: 34E4]

CAT#: AM00061PU-N

c Fos (FOS) pSer374 (incl. pos. control) mouse monoclonal antibody, clone 34E4, Purified



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CNY 5,973.00


货期*
5周

规格
    • 100 ug

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Specifications

Product Data
Clone Name 34E4
Applications ELISA, IHC, WB
Recommend Dilution Western Blot: 0.5 µg/ml for HRPO/ECL detection.
Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubation buffer.
ELISA: 0.1 µg/ml (protein ELISA).
Immunohistochemistry on frozen sections.
Reactivity Canine, Human
Host Mouse
Clonality Monoclonal
Immunogen Synthetic phosphopeptide conjugated to KLH.
Specificity This antibody specifically interacts with c-Fos phosphorylated at serine 374.
Formulation 1 ml 2 x PBS / 0.09 % Na-azide / PEG and Sucrose
State: Purified
State: Lyophilized purified IgG
Reconstitution Method Restore with 1 ml H2O (15 min, RT).
Purification Size exclusion chromatography
Conjugation Unconjugated
Storage Condition Store lyophilized (preferably in a desiccator) at -20°C and reconstituted (aliquote and freeze in liquid nitrogen) at -80°C.
Avoid repeated freezing and thawing.
Thaw aliquots at 37°C. Thawed aliquots may be stored at 4°C up to 3 months.
Gene Name Fos proto-oncogene, AP-1 transcription factor subunit
Background The immediated early gene product c-Fos is expressed following mitogenic stimulation. c-Fos functions as a sensor for MAPK signal duration. When MAPK activation is transient, MAPK activity declines before accumulation of the c-Fos protein. When MAPK activation is sustained, c-Fos is phosphorylated by MAPK at serine 374. Phosphorylation stabilizes the Fos protein and primes c-Fos for additional phosphorylation at threonine 325.
Synonyms FOS, G0S7
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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