CD19 Mouse Monoclonal Antibody [Clone ID: Bu12]

CAT#: AM01058FC-N

CD19 mouse monoclonal antibody, clone Bu12, FITC

Conjugation: Unconjugated FITC



Need it in bulk or conjugated?
Get a free quote

CNY 5,379.00


货期*
4周

规格
    • 100 ug

Product images

Specifications

Product Data
Clone Name Bu12
Applications FC
Recommend Dilution Flow Cytometry: 1/10; 10µl of the suggested working dilution to label 1x10e6 cells in 100µl.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Human EB-4 Burkitt lymphoma cell line.
Specificity This antibody recognises CD19, a 95kD cell surface glycoprotein, which is expressed on cells of the B cell lineage and follicular dendritic cells but absent on plasma cells. CD19 is an important signal transduction molecule which is involved in the regulation of B lymphocyte development, activation and differentiation.
Formulation Phosphate buffered saline pH7.4 containing 0.09% Sodium Azide (NaN3), 1% Bovine Serum Albumin
Label: FITC
State: Liquid purified IgG
Label: Fluorescein Isothiocyanate Isomer 1
Concentration lot specific
Purification Affinity chromatography on Protein G
Conjugation FITC
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name CD19 molecule
Background CD19 is a member of the immunoglobulin superfamily and has two Ig like domains. The CD19 molecule is expressed on 100% of the peripheral B cells as defined by expression of kappa or lamda light chains. It is expressed on approximately 10% of normal human peripheral blood cells and approximately 60% of splenic lymphocytes. It is not expressed on granulocytes, monocytes or T cells as defined by CD3 expression. CD19 defines a pan B antigen which is expressed from the earliest stages of B progenitor development, but is lost on terminal differentiation to plasma cells. It may also be present on some early myeloid progenitors, particularly those of the monoblastic type. The CD19 antigen is expressed on approximately 12% of peripheral blood lymphocytes. It appears to be expressed on myeloid leukemia cells, particularly those of monocytic lineage. Leukemia phenotype studies have demonstrated that the earliest and broadest B cell restricted antigen is the CD19 antigen.
Synonyms Leu-12, B-cell marker
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
Customer Reviews 
Loading...