ABL2 Mouse Monoclonal Antibody [Clone ID: 1H1B11]

Specifications

Product Data
Clone Name	1H1B11
Applications	ELISA, IF, WB
Recommend Dilution	ELISA: 1/10000. Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200-1/1000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of ABL2 expressed in E. Coli.
Specificity	Recognizes ABL2 (ARG, Abelson-related gene).
Formulation	State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	ABL proto-oncogene 2, non-receptor tyrosine kinase
Database Link	Entrez Gene 27 Human UniProt ID P42684
Background	ABL2 (ARG, Abelson-related gene) is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. ABL2 is expressed in both normal and tumor cells. The ABL2 gene product is expressed as two variants bearing different amino termini, both approximately 12-kb in length. c-Abl shows both cytoplasmic and nuclear localization，c-Abl is involved in two different chromosomal translocations present in human leukemias, which generate Bcr-Abl and TEL-Abl.
Synonyms	ABLL, ARG
Reference Data

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