c Abl (ABL1) Mouse Monoclonal Antibody [Clone ID: 7B11D6]

CAT#: AM06256SU-N

c Abl (ABL1) mouse monoclonal antibody, clone 7B11D6, Ascites



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CNY 5,346.00


货期*
5周

规格
    • 100 ul

Product images

Specifications

Product Data
Clone Name 7B11D6
Applications ELISA, WB
Recommend Dilution ELISA: 1/10000.
Western Blot: 1/500 - 1/2000.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Purified recombinant fragment of ABL1 (aa577-650) expressed in E. Coli.
Specificity Recognizes ABL1
Formulation State: Ascites
State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation Unconjugated
Storage Condition

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Gene Name ABL proto-oncogene 1, non-receptor tyrosine kinase
Background The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9;22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1. The ABL1 gene is expressed as either a 6- or 7-kb mRNA transcript, with alternatively spliced first exons spliced to the common exons 2-11.
Synonyms c-ABL, p150, JTK7, bcr/abl
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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