Prolactin Receptor (PRLR) Mouse Monoclonal Antibody [Clone ID: B6.2+PRLR742]

Specifications

Product Data
Clone Name	B6.2+PRLR742
Applications	FC, IF, IHC, IP, WB
Recommend Dilution	ELISA: Use BSA free Antibody for coating. Flow Cytometry: 0.5-1 μg/million cells. Immunofluorescence: 0.5-1 μg/ml. Western Blotting: 0.25-0.5 μg/ml. Immunoprecipitation: 0.5-1 μg/500 μg protein lysate. Immunohistochemistry on Frozen and Formalin-Fixed Paraffin Sections: 0.5-1.0 μg/ml for 30 minutes at RT. Staining of formalin/paraffin tissues requires digestion of tissue sections with pepsin at 1mg/ml Tris-HCl, pH 2.0 for 15 min at RT or 10 min at 37°C. Positive Control: Breast, placenta, liver or pancreas.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Semi-purified Human Prolactin Receptor (B6.2) and Recombinant Human Prolactin Receptor (PRLR742).
Specificity	It recognizes a protein of 70kDa, identified as Prolactin Receptor.  Cellular Localization: Cell surface and cytoplasmic.
Formulation	10mM PBS State: Purified State: Liquid purified IgG fraction from Bioreactor Concentrate Stabilizer: 0.05% BSA Preservative: 0.05% Sodium Azide
Concentration	lot specific
Purification	Protein A/G Chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C.
Predicted Protein Size	70 kDa
Gene Name	prolactin receptor
Database Link	Entrez Gene 5618 Human UniProt ID P16471
Background	Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor), which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated, at least in part, by two families of signaling molecules: Janus kinases and signal transducers and activators of transcription.
Synonyms	PRLR, PRL-R
Reference Data

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