LINC02210-CRHR1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, WB
Recommend Dilution	ELISA: 1/1000. Western blot: 1/100 - 1/500. Flow Cytometry: 1/10 - 1/50.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 95-128 amino acids from human CRHR1
Specificity	This antibody reacts to human CRFR1.
Formulation	PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% (W/V) sodium azide
Concentration	lot specific
Purification	Affinity chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	50719 Da
Gene Name	LINC02210-CRHR1 readthrough
Database Link	Entrez Gene 1394 HumanEntrez Gene 104909134 Human UniProt ID P34998
Background	This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants.
Synonyms	CRHR-1, CRFR, CRFR1, CRHR, Corticotropin-releasing factor receptor 1, CRF-R, CRF1, Corticotropin-releasing hormone receptor 1, CRH-R 1
Reference Data
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	Long-term depression, Neuroactive ligand-receptor interaction

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