Twist (TWIST1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA. Western Blot: 1/1000-1/5000. Immunohistochemistry: 1/100-1/1000.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide derived from N-terminal domain of Human Twist-1 protein
Specificity	This antibody reacts with Human 21 kDa TWIST1 protein.  It Does not cross reacts with Twist-2.
Formulation	0.1M Tris, 0.1M Glycine and 2% Sucrose State: Purified State: Lyophilized purified antibody Preservative: None
Reconstitution Method	Restore in distilled water.
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store the antibody at -20°C. Store reconstituted antibody at 2-8°C for one month or (in aliquots) at -20°C for longer Avoid repeated freezing and thawing.
Gene Name	twist family bHLH transcription factor 1
Database Link	Entrez Gene 7291 Human UniProt ID Q15672
Background	Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation. TWIST1 is a bHLH transcription factor and shares similarity with another bHLH transcription factor, Dermo1. The strongest expression of this mRNA is in placental tissue, in adults, mesodermally derived tissues express this mRNA preferentially. Mutations in this gene have been found in patients with Saethre-Chotzen syndrome.
Synonyms	Twist-related protein 1, TWIST, BHLHA38
Reference Data

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