PEG10 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 200-1000 WB positive control: 231 and A549 cells
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to C terminal 250 amino acids of human paternally expressed 10
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	80 kDa
Gene Name	paternally expressed 10
Database Link	NP_001035242 Entrez Gene 23089 Human UniProt ID Q86TG7
Background	This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs); RF1 and RF1/RF2; as well as retroviral-like slippage and pseudoknot elements; which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants; as well as from use of upstream non-AUG (CUG) start codon; have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas.
Synonyms	EDR; HB-1; Mar2; Mart2; MEF3L; RGAG3
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.