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MEK5 (MAP2K5) Rabbit Polyclonal Antibody
CAT＃: TA324157S
Anti-MAP2K5 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
CNY 3,080.00
Specifications
| Product Data | |
| Applications | IHC |
| Recommend Dilution | IHC: 50-200 Positive control: Human colon cancer Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Fusion protein corresponding to a region derived from 172-409 amino acids of human mitogen-activated protein kinase kinase 5 |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | mitogen-activated protein kinase kinase 5 |
| Database Link | |
| Background | The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3; as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. |
| Synonyms | dual specificity mitogen-activated protein kinase kinase 5; ERK kinase 5; HsT17454; MAPK; MAP kinase kinase MEK5b; MAPKK5; MEK5; mitogen-activated protein kinase kinase 5; PRKMK5 |
| Reference Data | |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | Gap junction, MAPK signaling pathway, Neurotrophin signaling pathway |
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