Factor XIIIa (F13A1) Rabbit Monoclonal Antibody [Clone ID: EP3372]

Specifications

Product Data
Clone Name	EP3372
Applications	IHC
Recommend Dilution	IHC: 1:100 - 1:500
Reactivity	Human
Host	Rabbit
Clonality	Monoclonal
Formulation	This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	coagulation factor XIII A chain
Database Link	NP_000120 Entrez Gene 2162 Human UniProt ID P00488
Synonyms	F13A
Note	Factor XIIIa is a blood proenzyme that has been identified in platelets, megakaryocytes, and fibroblast-like mesenchymal or histiocytic cells present in the placenta, uterus, and prostate; it is also present in monocytes, macrophages, and dermal dendritic cells. Anti-factor XIIIa has been found to be useful in differentiating between dermatofibroma (90% (+)), dermatofibrosarcoma protuberans (25%(+)), and desmoplastic malignant melanoma (0%(+)). Anti-factor XIIIa positivity is also seen in capillary hemangioblastoma (100%(+)), hemangioendothelioma (100%(+)), hemangiopericytoma (100%(+)), xanthogranuloma (100%(+)), xanthoma (100%(+)), hepatocellular carcinoma (93%(+)), glomus tumor (80%(+)), and meningioma (80 % (+)).
Reference Data
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	Complement and coagulation cascades

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