ETS1 associated protein II (TDP2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Mouse small intestines tissue lysate IHC: 50-300 Positive control: Human cervical cancer Predicted cell location: Cytoplasm and Nucleus
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human TDP2
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	41 kDa
Gene Name	tyrosyl-DNA phosphodiesterase 2
Database Link	NP_057698 Entrez Gene 56196 MouseEntrez Gene 51567 Human UniProt ID O95551
Background	This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors.
Synonyms	AD022; dJ30M3.3; EAP2; EAPII; hTDP2; TTRAP
Reference Data
Protein Families	Druggable Genome, Stem cell - Pluripotency, Transcription Factors

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