COX2 (PTGS2) Rabbit Monoclonal Antibody [Clone ID: R04-3I1]

CAT#: TA385085S

Cyclooxygenase 2 Rabbit monoclonal Antibody

Size: 20 ul 100 ul



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CNY 800.00


货期*
2周

规格
    • 20 ul

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Specifications

Product Data
Clone Name R04-3I1
Applications IHC, WB
Recommend Dilution WB: 1/1000
IHC: 1/20
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Monoclonal
Immunogen A synthetic peptide of human COX2
Formulation 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration lot specific
Purification Affinity Purified
Conjugation Unconjugated
Storage Condition Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size Calculated MW: 69 kDa; Observed MW: 69 kDa
Gene Name prostaglandin-endoperoxide synthase 2
Background Swiss-Prot Acc.P35354.Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis (PubMed:26859324, PubMed:27226593). Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis.
Synonyms COX-2; COX2; Cyclooxygenase-2; GRIPGHS; hCox-2; PGG/HS; PGHS-2; PHS-2
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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