Von Hippel Lindau (VHL) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1E1]

CAT#: TA506222BM

VHL mouse monoclonal antibody,clone 1E1, HRP conjugated

Conjugation: Unconjugated Biotin HRP



  View other "OTI1E1" antibodies (4)

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CNY 3,990.00


货期*
2周

规格
    • 100 ul

经常一起买 (3)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

CNY 300.00
CNY 1,430.00


Recombinant protein of human von Hippel-Lindau tumor suppressor (VHL), transcript variant 1, 20 µg
    • 20 ug

CNY 2,900.00
CNY 6,650.00


Transient overexpression lysate of von Hippel-Lindau tumor suppressor (VHL), transcript variant 1
    • 100 ug

CNY 3,080.00

Specifications

Product Data
Clone Name OTI1E1
Applications IHC, WB
Recommend Dilution WB 1:4000, IHC 1:150
Reactivity Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human VHL(NP_000542) produced in HEK293T cell.
Formulation PBS (pH 7.4) containing 1% BSA, 50% glycerol.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation HRP
Storage Condition Store at -20°C as received.
Predicted Protein Size 24 kDa
Gene Name von Hippel-Lindau tumor suppressor
Background Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome. The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin-2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. RNA polymerase II subunit POLR2G/RPB7 is also reported to be a target of this protein. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
Synonyms HRCA1; pVHL; RCA1; VHL1
Reference Data
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Pathways in cancer, Renal cell carcinoma, Ubiquitin mediated proteolysis
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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