MSH6 (NM_000179) Human 3' UTR Clone

Specifications

Product Data
Product Name	MSH6 (NM_000179) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	GTBP; GTMBP; HNPCC5; HSAP; MMRCS3; p160
ACCN	NM_000179
Insert Size	123 bp
Sequence Data	Insert Sequence (showhide) >SC202240 3’UTR clone of NM_000179 The sequence shown below is from the reference sequence of NM_000179. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AAATTGCTGACTTTGATTAAGGAATTATAGACTGACTACATTGGAAGCTTTGAGTTGACTTCTGACAAA GGTGGTAAATTCAGACAACATTATGATCTAATAAACTTTATTTTTTAAAAATGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000179.3
Synonyms	GTBP; GTMBP; HNPCC5; HSAP; MMRCS3; p160
Summary	This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013]
Locus ID	2956
MW	4.7

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