DNMT3B (NM_175849) Human 3' UTR Clone

CAT#: SC214755

3' UTR clone of DNA (cytosine-5-)-methyltransferase 3 beta (DNMT3B) transcript variant 3 for miRNA target validation



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CNY 4,845.00


货期*
3周

规格
    • 10 ug

Product images

经常一起买 (2)
Firefly luciferase assay kit, 150 assays
    • 1 kit

CNY 1,520.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00

Specifications

Product Data
Product Name DNMT3B (NM_175849) Human 3' UTR Clone
Vector pMirTarget
Synonyms ICF; ICF1; M.HsaIIIB
ACCN NM_175849
Insert Size 1483 bp
Sequence Data
>SC214755 3’UTR clone of NM_175849
The sequence shown below is from the reference sequence of NM_175849. The complete sequence of this clone may contain minor differences, such as SNPs.
Blue=Stop Codon Red=Cloning site

GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG
TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC
CCTCTGAAGGACTACTTTGCATGTGAATAGTTCCAGCCAGGCCCCAAGCCCACTGGGGTGTGTGGCAGA
GCCAGGACCCAGGAGGTGTGATTCCTGAAGGCATCCCCAGGCCCTGCTCTTCCTCAGCTGTGTGGGTCA
TACCGTGTACCTCAGTTCCCTCTTGCTCAGTGGGGGCAGAGCCACCTGACTCTTGCAGGGGTAGCCTGA
GGTGCCGCCTCCTTGTGCACAAATCAGACCTGGCTGCTTGGAGCAGCCTAACACGGTGCTCATTTTTTC
TTCTCCTAAAACTTTAAAACTTGAAGTAGGTAGCAACGTGGCTTTTTTTTTTTCCCTTCCTGGGTCTAC
CACTCAGAGAAACAATGGCTAAGATACCAAAACCACAGTGCCGACAGCTCTCCAATACTCAGGTTAATG
CTGAAAAATCATCCAAGACAGTTATTGCAAGAGTTTAATTTTTGAAAACTGGCTACTGCTCTGTGTTTA
CAGACGTGTGCAGTTGTAGGCATGTAGCTACAGGACATTTTTAAGGGCCCAGGATCGTTTTTTCCCAGG
GCAAGCAGAAGAGAAAATGTTGTATATGTCTTTTACCCGGCACATTCCCCTTGCCTAAATACAAGGGCT
GGAGTCTGCACGGGACCTATTAGAGTATTTTCCACAATGATGATGATTTCAGCAGGGATGACGTCATCA
TCACATTCAGGGCTATTTTTTCCCCCACAAACCCAAGGGCAGGGGCCACTCTTAGCTAAATCCCTCCCC
GTGACTGCAATAGAACCCTCTGGGGAGCTCAGGAAGGGGTGTGCTGAGTTCTATAATATAAGCTGCCAT
ATATTTTGTAGACAAGTATGGCTCCTCCATATCTCCCTCTTCCCTAGGAGAGGAGTGTGAAGCAAGGAG
CTTAGATAAGACACCCCCTCAAACCCATTCCCTCTCCAGGAGACCTACCCTCCACAGGCACAGGTCCCC
AGATGAGAAGTCTGCTACCCTCATTTCTCATCTTTTTACTAAACTCAGAGGCAGTGACAGCAGTCAGGG
ACAGACATACATTTCTCATACCTTCCCCACATCTGAGAGATGACAGGGAAAACTGCAAAGCTCGGTGCT
CCCTTTGGAGATTTTTTAATCCTTTTTTATTCCATAAGAAGTCGTTTTTAGGGAGAACGGGAATTCAGA
CAAGCTGCATTTCAGAAATGCTGTCATAATGGTTTTTAACACCTTTTACTCTTCTTACTGGTGCTATTT
TGTAGAATAAGGAACAACGTTGACAAGTTTTGTGGGGCTTTTTATACACTTTTTAAAATCTCAAACTTC
TATTTTTATGTTTAACGTTTTCATTAAAATTTTTTTTGTAACTGGAGCCACGACGTAACAAATATGGGG
AAAAAACTGTGCCTTGTTTCAACAGTTTTTGCTAATTTTTAGGCTGAAAGATGACGGATGCCTAGAGTT
TACCTTATGTTTAATTAAAATCAGTATTTGTCTA
ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA
CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites SgfI-MluI     
OTI Disclaimer Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq NM_175849.2
Synonyms ICF; ICF1; M.HsaIIIB
Summary CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined. [provided by RefSeq, May 2011]
Locus ID 1789
MW 56.5
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