United States
Germany
Japan
United Kingdom
China
Fanci (NM_145946) Mouse Tagged ORF Clone
CAT＃: MR221899
- TrueORF®
Fanci (Myc-DDK-tagged) - Mouse Fanconi anemia, complementation group I (Fanci)
ORF Plasmid: tGFP
"NM_145946" in other vectors (4)
Need custom modification / cloning service?
Get a free quote
CNY 13,300.00
| Cited in 1 publication. |
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | MGC38195; MGC38407 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MR221899 representing NM_145946
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGATCTGAAAATTTTATCTCTAGCAACAGATAAAACTACAGATAAACTGCAGGAGTTTCTTCAAACCC TGAAAGATGATGATTTGGCCAGTCTCCTTCAGAACCAAGCGGTGAAAGGAAGAGCTGTTGGAACGCTCCT GAGAGCCGTCCTCAAAGGCTCCCCCTGCTCTGAGGAAGATGGAGCCCTTAGGAGATACAAGATATATTCT TGCTGTATCCAGTTGGTTGAATCGGGAGATTTGCAGCAAGATGTCGCATCAGAGATCATAGGATTACTAA TGCTGGAGGTCCACCATTTTCCAGGCCCATTACTTGTTGACTTGGCTAGTGACTTTGTGGGTGCTGTCCG AGAGGACCGCCTAGTGAATGGAAAATCTTTGGAGTTATTACCCATCATCCTTACTGCCTTGGCCACCAAG AAGGAAGTCCTCGCTTGTGGGAAAGGTGATTTGAATGGGGAAGAATATAAGAGGCAGTTGATTGACACCC TGTGTTCTGTCAGATGGCCTCAACGGTACATGATCCAGCTCACTTCTGTGTTCAAGGATGTCTGTCTAAC GCCAGAAGAGATGAATCTCGTGGTGGCCAAAGTGTTGACGATGTTCTCAAAGTTGAATCTTCAAGAAATT CCACCTTTGGTCTATCAGCTTCTGGTTCTCTCTTCCAAGGGAAGCAGAAGGAGTGTTCTGGACGGAATCA TAGCCTTCTTCAGGGAGCTGGATAAGCAGCACAGGGAGGAACAGAGCAGCGATGAGTTGTCAGAGCTTAT TACTGCCCCAGCAGACGAACTCTATCACGTGGAAGGCACCGTTATTCTGCACATCGTATTTGCCATCAAA CTGGACTGTGAATTAGGCAGAGAACTTCTGAAACACTTGAAGGCTGGACAGCAGGGGGATCCCAGTAAAT GCCTATGTCCCTTCAGCATCGCTCTTCTCCTCTCTCTCACGAGAATACAGAGATTTGAGGAACAGGTGTT TGATCTTTTAAAGACTTCTGTTGTAAAAAGCTTCAAGGATCTTCAGCTCCTCCAAGGCTCCAAGTTTCTT CAGACTCTCGTCCCCCAGAGAACTTGTGTTTCAACCATGATCTTAGAAGTGGTGAGGAACAGTGTTCATA GTTGGGATCATGTAACTCAAGGTCTGATAGAATTTGGTTTCATCTTGATGGATTCCTATGGGCCAAAGAA GATTCTTGATGGAAAAGCTGTTGAAATTGGCACCAGTCTTTCTAAAATGACAAACCAGCACGCATGTAAG CTGGGAGCTAATATCTTATTGGAAACCTTTAAAATCCACGAGATGATCAGACAAGAAATTCTGGAGCAAG TCCTCAACAGAGTTGTTACGCGAACATCCTCTCCCATCAATCATTTCTTAGACTTGTTTTCAGATATCAT CATGTATGCACCTTTAATTCTTCAGAACTGTTCAAAAGTCACGGAAACTTTTGACTATTTGACCTTTCTG CCCCTCCAGACCGTGCAAGGGCTGCTCAAGGCGGTGCAGCCGCTTCTCAAGATCAGCATGTCGATGAGAG ACTCCTTGATCCTCGTCTTGCGGAAAGCTATGTTTGCCAGCCAGCTGGATGCCCGGAAATCTGCAGTTGC TGGGTTTTTGCTGCTCCTAAAGAACTTTAAAGTCCTAGGCAGCCTGCCGTCCTCACAGTGCACACAGTCT ATTGGTGTCACGCAGGTGCGCGTGGACGTTCACAGCCGATACAGCGCTGTCGCCAACGAGACCTTCTGCC TTGAGATCATAGACAGCTTGAAACGAAGCTTAGGGCAGCAGGCAGACATCCGGCTCATGCTTTACGACGG TTTCTACGATGTCCTTCGACGGAACTCTCAGCTGGCTAGTTCAATCATGCAGACTCTCTTCTCACAGTTA AAACAGTTCTATGAGCCAGAGCCTGATCTGCTACCTCCTCTGAAACTAGGAGCTTGTGTTCTGACCCAAG GAAGTCAGATCTTTCTACAAGAGCCGCTGGATCATCTGCTGTCTTGCATTCAGCATTGCTTGGCCTGGTA TAAGAGCAGAGTCGTCCCCCTGCAACAAGGAGATGAAGGAGAGGAGGAGGAGGAGGAGTTGTACTCCGAG CTGGATGATATGTTGGAGTCCATTACTGTCAGAATGATCAAGAGTGAGCTGGAAGACTTTGAGCTGGATA AATCAGCAGATTTCTCTCAGAACACTAATGTCGGCATCAAGAATAATATCTGTGCGTGTCTCATCATGGG AGTGTGTGAAGTTCTAATGGAATATAATTTCTCCATAAGTAACTTCAGCAAGAGTAAGTTTGAGGAGATC CTGAGCCTCTTCACATGTTACAAGAAGTTCTCTGACATCCTCAGTGAGAAAGCTGGCAAAGGCAAGGCTA AGATGACCAGTAAAGTCAGCGACAGTCTCCTGTCCTTGAAGTTTGTGTCTGATCTCCTCACTGCTCTCTT CAGAGACAGCATCCAGAGTCATGAAGAGAGTCTGTCTGTCCTGCGGTCCAGCGGCGAGTTTATGCACTAT GCAGTGAACGTCACTTTGCAGAAGATTCAGCAGCTAATACGAACAGGGCATGTGAGTGGCCCTGATGGTC AGAACCCAGACAAGATCTTTCAGAACCTCTGTGACATAACTCGGGTCCTGCTGTGGAGATACACATCAAT TCCTACATCCGTGGAGGAGTCGGGGAAGAAGGAGAAGGGAAAGAGCATCTCGCTGTTGTGCTTGGAGGGC TTGCAGAAGACGTTCAGTGTGGTGCTGCAGTTCTACCAGCCCAAGGTCCAGCAGTTTCTCCAGGCTCTGG ATGTCATGGGCACAGAAGAAGAAGAAGCAGGTGTCACTGTCACTCAGAGGGCCTCGTTCCAGATCCGGCA GTTTCAGAGGTCGTTGTTGAATCTGCTGAGCAGCGAAGAGGACGATTTTAACAGTAAAGAGGCCCTCCTG CTCATCGCGGTGCTGTCCACCTTGTCCAGGCTGCTGGAGCCCACCTCTCCTCAGTTTGTGCAGATGTTAT CCTGGACATCTAAGATTTGCAAGGAATACAGCCAGGAGGATGCCTCATTTTGCAAGAGTTTGATGAACCT GTTCTTCAGCCTGCATGTCTTATATAAGAGTCCTGTCACCCTGCTTCGTGACTTGTCCCAGGATATCCAT GGGCAGCTGGGAGACATAGATCAAGATGTAGAGATTGAGAAGACAGACCACTTTGCTGTGGTGAATTTGA GAACGGCTGCCCCCACTGTCTGTTTACTTGTTCTGAGTCAGGCTGAGAAAGTCCTAGAAGAAGTGGACTG GTTAATCGCCAAGATCAAGGGCTCAGCAAACCAAGAAACGCTATCAGATAAAGTGACTCCAGAAGATGCC TCTTCTCAAGCCGTTCCACCAACTCTTCTCATTGAGAAAGCTATCGTCATGCAACTGGGAACTCTGGTAA CGTTCTTCCATGAGCTCGTGCAGACAGCCCTGCCATCAGGCAGCTGTGTAGACACTCTACTGAAGGGCCT GTCCAAGATCTACAGCACCCTAACAGCATTCGTCAAATATTATCTCCAGGTATGTCAGAGCTCCAGAGGA ATTCCAAACACTGTGGAAAAACTGGTGAAGCTGTCGGGCTCTCATCTGACCCCCGTATGTTACTCTTTCA TTTCTTATGTACAAAATAAGAGCAGTGACGCCCCAAAGTGCTCAGAAAAGGAGAAGGCTGCAGTGAGCAC AACCATGGCCAAAGTTCTTCGTGAAACCAAGCCAATCCCTAACCTTGTCTTTGCCATTGAACAGTATGAA AAATTTCTTATCCAACTGTCTAAAAAGTCCAAGGTAAACCTGATGCAGCACATGAAGCTGAGTACTTCTC GGGACTTCAAGATCAAAGGCAGTGTCCTCGACATGGTTCTTCGAGAGGATGAGGAAGACGAAAACGAAGA GGGCACTGCATCAGCACATACACAGCAGGACAGAGAACCAGCCAAGAAGAGGAGGAAGAAATGCCTGAGT ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR221899 representing NM_145946
Red=Cloning site Green=Tags(s) MDLKILSLATDKTTDKLQEFLQTLKDDDLASLLQNQAVKGRAVGTLLRAVLKGSPCSEEDGALRRYKIYS CCIQLVESGDLQQDVASEIIGLLMLEVHHFPGPLLVDLASDFVGAVREDRLVNGKSLELLPIILTALATK KEVLACGKGDLNGEEYKRQLIDTLCSVRWPQRYMIQLTSVFKDVCLTPEEMNLVVAKVLTMFSKLNLQEI PPLVYQLLVLSSKGSRRSVLDGIIAFFRELDKQHREEQSSDELSELITAPADELYHVEGTVILHIVFAIK LDCELGRELLKHLKAGQQGDPSKCLCPFSIALLLSLTRIQRFEEQVFDLLKTSVVKSFKDLQLLQGSKFL QTLVPQRTCVSTMILEVVRNSVHSWDHVTQGLIEFGFILMDSYGPKKILDGKAVEIGTSLSKMTNQHACK LGANILLETFKIHEMIRQEILEQVLNRVVTRTSSPINHFLDLFSDIIMYAPLILQNCSKVTETFDYLTFL PLQTVQGLLKAVQPLLKISMSMRDSLILVLRKAMFASQLDARKSAVAGFLLLLKNFKVLGSLPSSQCTQS IGVTQVRVDVHSRYSAVANETFCLEIIDSLKRSLGQQADIRLMLYDGFYDVLRRNSQLASSIMQTLFSQL KQFYEPEPDLLPPLKLGACVLTQGSQIFLQEPLDHLLSCIQHCLAWYKSRVVPLQQGDEGEEEEEELYSE LDDMLESITVRMIKSELEDFELDKSADFSQNTNVGIKNNICACLIMGVCEVLMEYNFSISNFSKSKFEEI LSLFTCYKKFSDILSEKAGKGKAKMTSKVSDSLLSLKFVSDLLTALFRDSIQSHEESLSVLRSSGEFMHY AVNVTLQKIQQLIRTGHVSGPDGQNPDKIFQNLCDITRVLLWRYTSIPTSVEESGKKEKGKSISLLCLEG LQKTFSVVLQFYQPKVQQFLQALDVMGTEEEEAGVTVTQRASFQIRQFQRSLLNLLSSEEDDFNSKEALL LIAVLSTLSRLLEPTSPQFVQMLSWTSKICKEYSQEDASFCKSLMNLFFSLHVLYKSPVTLLRDLSQDIH GQLGDIDQDVEIEKTDHFAVVNLRTAAPTVCLLVLSQAEKVLEEVDWLIAKIKGSANQETLSDKVTPEDA SSQAVPPTLLIEKAIVMQLGTLVTFFHELVQTALPSGSCVDTLLKGLSKIYSTLTAFVKYYLQVCQSSRG IPNTVEKLVKLSGSHLTPVCYSFISYVQNKSSDAPKCSEKEKAAVSTTMAKVLRETKPIPNLVFAIEQYE KFLIQLSKKSKVNLMQHMKLSTSRDFKIKGSVLDMVLREDEEDENEEGTASAHTQQDREPAKKRRKKCLS TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_145946 |
| ORF Size | 3990 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_145946.2, NP_666058.2 |
| RefSeq Size | 4621 bp |
| RefSeq ORF | 3993 bp |
| Locus ID | 208836 |
| UniProt ID | Q8K368 |
| MW | 149.8 kDa |
| Gene Summary | Plays an essential role in the repair of DNA double-strand breaks by homologous recombination and in the repair of interstrand DNA cross-links (ICLs) by promoting FANCD2 monoubiquitination by FANCL and participating in recruitment to DNA repair sites. Required for maintenance of chromosomal stability. Specifically binds branched DNA: binds both single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA). Participates in S phase and G2 phase checkpoint activation upon DNA damage.[UniProtKB/Swiss-Prot Function] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Homocysteine inhibits neural stem cells survival by inducing DNA interstrand cross-links via oxidative stress
,Wang, D;Chen, YM;Ruan, MH;Zhou, AH;Qian, Y;Chen, C;,
Neurosci. Lett.
,PubMed ID 27773793
[Fanci]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC224271 | Fanci (untagged) - Mouse Fanconi anemia, complementation group I (Fanci), (10ug) |
CNY 17,100.00 |
|
| MG221899 | Fanci (tGFP-tagged) - Mouse Fanconi anemia complementation group I (Fanci), (10ug) |
CNY 14,630.00 |
|
| MR221899L3 | Lenti ORF clone of Fanci (Myc-DDK-tagged) - Mouse Fanconi anemia, complementation group I (Fanci) |
CNY 15,200.00 |
|
| MR221899L4 | Lenti ORF clone of Fanci (mGFP-tagged) - Mouse Fanconi anemia, complementation group I (Fanci) |
CNY 15,200.00 |
