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GNRHR (NM_000406) Human Tagged Lenti ORF Clone
CAT＃: RC214403L2
- LentiORF®
Lenti ORF clone of Human gonadotropin-releasing hormone receptor (GNRHR), transcript variant 1, mGFP tagged
"NM_000406" in other vectors (6)
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CNY 5,890.00
Product images
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | mGFP |
| Synonyms | GNRHR1; GRHR; HH7; LHRHR; LRHR |
| Vector | pLenti-C-mGFP |
| E. coli Selection | Chloramphenicol (34 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC214403).
|
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_000406 |
| ORF Size | 984 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000406.2 |
| RefSeq Size | 5843 bp |
| RefSeq ORF | 987 bp |
| Locus ID | 2798 |
| UniProt ID | P30968 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | GnRH signaling pathway, Neuroactive ligand-receptor interaction |
| MW | 37.6 kDa |
| Gene Summary | This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene. [provided by RefSeq, Jul 2008] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC214403 | GNRHR (Myc-DDK-tagged)-Human gonadotropin-releasing hormone receptor (GNRHR), transcript variant 1 |
CNY 2,400.00 |
|
| RC214403L1 | Lenti ORF clone of Human gonadotropin-releasing hormone receptor (GNRHR), transcript variant 1, Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC214403L3 | Lenti ORF clone of Human gonadotropin-releasing hormone receptor (GNRHR), transcript variant 1, Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC214403L4 | Lenti ORF clone of Human gonadotropin-releasing hormone receptor (GNRHR), transcript variant 1, mGFP tagged |
CNY 4,800.00 |
|
| RG214403 | GNRHR (tGFP-tagged) - Human gonadotropin-releasing hormone receptor (GNRHR), transcript variant 1 |
CNY 4,000.00 |
|
| SC316990 | GNRHR (untagged)-Human gonadotropin-releasing hormone receptor (GNRHR), transcript variant 1 |
CNY 2,400.00 |
