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PTPRB (NM_001109754) Human Tagged ORF Clone
CAT＃: RG226479
- TrueORF®
PTPRB (tGFP-tagged) - Human protein tyrosine phosphatase, receptor type, B (PTPRB), transcript variant 1
ORF Plasmid: DDK
"NM_001109754" in other vectors (2)
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CNY 23,536.00
货期*
现货
规格
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经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | HPTP-BETA; HPTPB; PTPB; R-PTP-BETA; VEPTP |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG226479 representing NM_001109754
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAGGCTGAATTTTACATGGTGATTCTTACCTGCTTGATCTTCAGGAACTCAGAAGGGTTTCAGATTG TCCATGTCCAGAAACAACAGTGTCTTTTCAAAAATGAGAAAGTGGTCGTGGGCTCATGCAACAGGACCAT CCAGAACCAGCAGTGGATGTGGACTGAGGATGAAAAGCTCCTTCATGTTAAATCTGCACTGTGCTTGGCC ATCTCCAACTCTTCCCGCGGCCCCTCCCGCTCAGCCATCTTGGACCGCTGTTCCCAGGCACCCCGATGGA CCTGCTATGATCAGGAAGGCTTCCTTGAGGTGGAAAATGCCTCTCTCTTTCTCCAGAAACAAGGCTCCAG AGTAGTGGTCAAGAAGGCCAGGAAATACCTCCATAGCTGGATGAAAATAGATGTCAACAAGGAGGGAAAA CTGGTCAATGAAAGCCTCTGTTTACAAAAAGCTGGCCTGGGAGCAGAAGTTTCGGTGAGGAGCACTAGAA ACACGGCTCCACCCCAGATTCTCACTACCTTTAATGCAGTTCCAGATGGCCTGGTATTCCTTATTAGGAA TACCACAGAGGCCTTCATCAGAAATGCTGCAGAAAACTACAGCCAAAACAGCAGCGAGAGGCAGCATCCC AATCTGCACATGACTGGAATTACAGACACATCATGGGTTTTGTCGACTACTCAGCCCTTCTCCAGCACCA CTGAAGAGACTGGACTGGCGGAGCCAGAGAGATGTAACTTCACCCTGGCGGAGTCCAAGGCCTCCAGCCA TTCTGTGTCTATCCAGTGGAGAATTTTGGGCTCACCCTGTAACTTTAGCCTCATCTATAGCAGTGACACC CTGGGGGCCGCGTTGTGCCCTACCTTTCGGATAGACAACACCACATACGGATGTAACCTTCAAGATTTAC AAGCAGGAACCATCTATAACTTCAGGATTATTTCTCTGGATGAAGAGAGAACAGTGGTCTTGCAAACAGA TCCTTTACCTCCTGCTAGGTTTGGAGTCAGTAAAGAGAAGACGACTTCAACCAGCTTGCATGTTTGGTGG ACTCCTTCTTCCGGAAAAGTCACCTCATATGAGGTGCAATTATTTGATGAAAATAACCAAAAGATACAGG GGGTTCAAATTCAAGAAAGTACTTCATGGAATGAATACACTTTTTTCAATCTCACTGCTGGTAGTAAATA CAATATTGCCATCACAGCTGTTTCTGGAGGAAAACGTTCTTTTTCAGTTTATACCAATGGATCAACAGTG CCATCTCCAGTGAAAGATATTGGTATTTCCACAAAAGCCAATTCTCTCCTGATTTCCTGGTCCCATGGTT CTGGGAATGTGGAACGATACCGGCTGATGCTAATGGATAAAGGGATCCTAGTTCATGGCGGTGTTGTGGA CAAACATGCTACTTCCTATGCTTTTCACGGGCTGACCCCTGGCTACCTCTACAACCTCACTGTTATGACT GAGGCTGCAGGGCTGCAAAACTACAGGTGGAAACTAGTCAGGACAGCCCCCATGGAAGTCTCAAATCTGA AGGTGACAAATGATGGCAGTTTGACCTCTCTAAAAGTCAAATGGCAAAGACCTCCTGGAAATGTGGATTC TTACAATATCACCCTGTCTCACAAAGGGACCATCAAGGAATCCAGAGTATTAGCACCTTGGATTACTGAA ACTCACTTTAAAGAGTTAGTCCCCGGTCGACTTTATCAAGTTACTGTCAGCTGTGTCTCTGGTGAACTGT CTGCTCAGAAGATGGCAGTGGGCAGAACATTTCCAGACAAAGTTGCAAACCTGGAGGCAAACAATAATGG CAGGATGAGGTCTCTTGTAGTGAGCTGGTCGCCCCCTGCTGGAGACTGGGAGCAGTATCGGATCCTACTC TTCAATGATTCTGTGGTGCTGCTCAACATCACTGTGGGAAAGGAAGAAACACAGTATGTCATGGATGACA CGGGGCTCGTACCGGGAAGACAGTATGAGGTGGAAGTCATTGTTGAGAGTGGAAATTTGAAGAATTCTGA GCGTTGCCAAGGCAGGACAGTCCCCCTGGCTGTCCTCCAGCTTCGTGTCAAACATGCCAATGAAACCTCA CTGAGTATCATGTGGCAGACCCCTGTAGCAGAATGGGAGAAATACATCATTTCCCTAGCTGACAGAGACC TCTTACTGATCCACAAGTCACTCTCCAAAGATGCCAAAGAATTCACTTTTACTGACCTGGTGCCTGGACG AAAATACATGGCTACAGTCACCAGTATTAGTGGAGACTTAAAAAATTCCTCTTCAGTAAAAGGAAGAACA GTGCCTGCCCAAGTGACTGACTTGCATGTGGCCAACCAAGGAATGACCAGTAGTCTGTTTACTAACTGGA CCCAGGCACAAGGAGACGTAGAATTTTACCAAGTCTTACTGATCCATGAAAATGTGGTCATTAAAAATGA AAGCATCTCCAGTGAGACCAGCAGATACAGCTTCCACTCTCTCAAGTCCGGCAGCCTGTACTCCGTGGTG GTAACAACAGTGAGTGGAGGGATCTCTTCCCGACAAGTGGTTGTGGAGGGAAGAACAGTCCCTTCCAGTG TGAGTGGAGTAACGGTGAACAATTCCGGTCGTAATGACTACCTCAGCGTTTCCTGGCTGCTGGCGCCCGG AGATGTGGATAACTATGAGGTAACATTGTCTCATGACGGCAAGGTGGTTCAGTCCCTTGTCATTGCCAAG TCTGTCAGAGAATGTTCCTTCAGCTCCCTCACCCCAGGCCGCCTCTACACCGTGACCATAACTACAAGGA GTGGCAAGTATGAAAATCACTCCTTCAGCCAAGAGCGGACAGTGCCTGACAAAGTCCAGGGAGTCAGTGT TAGCAACTCAGCCAGGAGTGACTATTTAAGGGTATCCTGGGTGCATGCCACTGGAGACTTTGATCACTAT GAAGTCACCATTAAAAACAAAAACAACTTCATTCAAACTAAAAGCATTCCCAAGTCAGAAAACGAATGTG TATTTGTTCAGCTAGTCCCTGGACGGTTGTACAGTGTCACTGTTACTACAAAAAGTGGACAATATGAAGC CAATGAACAAGGGAATGGGAGAACAATTCCAGAGCCTGTTAAGGATCTAACATTGCGCAACAGGAGCACT GAGGACTTGCATGTGACTTGGTCAGGAGCTAATGGGGATGTCGACCAATATGAGATCCAGCTGCTCTTCA ATGACATGAAAGTATTTCCTCCTTTTCACCTTGTAAATACCGCAACCGAGTATCGATTTACTTCCCTAAC ACCAGGCCGCCAATACAAAATTCTTGTCTTGACGATTAGCGGGGATGTACAGCAGTCAGCCTTCATTGAG GGCTTCACAGTTCCTAGTGCTGTCAAAAATATTCACATTTCTCCCAATGGAGCAACAGATAGCCTGACGG TGAACTGGACTCCTGGTGGGGGAGACGTTGATTCCTACACGGTGTCGGCATTCAGGCACAGTCAAAAGGT TGACTCTCAGACTATTCCCAAGCACGTCTTTGAGCACACGTTCCACAGACTGGAGGCCGGGGAGCAGTAC CAGATCATGATTGCCTCAGTCAGCGGGTCCCTGAAGAATCAGATAAATGTGGTTGGGCGGACAGTTCCAG CATCTGTCCAAGGAGTAATTGCAGACAATGCATACAGCAGTTATTCCTTAATAGTAAGTTGGCAAAAAGC TGCTGGTGTGGCAGAAAGATATGATATCCTGCTTCTAACTGAAAATGGAATCCTTCTGCGCAACACATCA GAGCCAGCCACCACTAAGCAACACAAATTTGAAGATCTAACACCAGGCAAGAAATACAAGATACAGATCC TAACTGTCAGTGGAGGCCTCTTTAGCAAGGAAGCCCAGACTGAAGGCCGAACAGTCCCAGCAGCTGTCAC CGACCTGAGGATCACAGAGAACTCCACCAGGCACCTGTCCTTCCGCTGGACCGCCTCAGAGGGGGAGCTC AGCTGGTACAACATCTTTTTGTACAACCCAGATGGGAATCTCCAGGAGAGAGCTCAAGTTGACCCACTAG TCCAGAGCTTCTCTTTCCAGAACTTGCTACAAGGCAGAATGTACAAGATGGTGATTGTAACTCACAGTGG GGAGCTGTCTAATGAGTCTTTCATATTTGGTAGAACAGTCCCAGCCTCTGTGAGTCATCTCAGGGGGTCC AATCGGAACACGACAGACAGCCTTTGGTTCAACTGGAGTCCAGCCTCTGGGGACTTTGACTTTTATGAGC TGATTCTCTATAATCCCAATGGCACAAAGAAGGAAAACTGGAAAGACAAGGACCTGACGGAGTGGCGGTT TCAAGGCCTTGTTCCTGGAAGGAAGTACGTGCTGTGGGTGGTAACTCACAGTGGAGATCTCAGCAATAAA GTCACAGCGGAGAGCAGAACAGCTCCAAGTCCTCCCAGTCTTATGTCATTTGCTGACATTGCAAACACAT CCTTGGCCATCACGTGGAAAGGGCCCCCAGACTGGACAGACTACAACGACTTTGAGCTGCAGTGGTTGCC CAGAGATGCACTTACTGTCTTCAACCCCTACAACAACAGAAAATCAGAAGGACGCATTGTGTATGGTCTT CGTCCAGGGAGATCCTATCAATTCAACGTCAAGACTGTCAGTGGTGATTCCTGGAAAACTTACAGCAAAC CAATTTTTGGATCTGTGAGGACAAAGCCTGACAAGATACAAAACCTGCATTGCCGGCCTCAGAACTCCAC GGCCATTGCCTGTTCTTGGATCCCTCCTGATTCTGACTTTGATGGTTATAGTATTGAATGCCGGAAAATG GACACCCAAGAAGTTGAGTTTTCCAGAAAGCTGGAGAAAGAAAAATCTCTGCTCAACATCATGATGCTAG TGCCCCATAAGAGGTACCTGGTGTCCATCAAAGTGCAGTCGGCCGGCATGACCAGCGAGGTGGTTGAAGA CAGCACTATCACAATGATAGACCGCCCCCCTCCTCCACCCCCACACATTCGTGTGAATGAAAAGGATGTG CTAATTAGCAAGTCTTCCATCAACTTTACTGTCAACTGCAGCTGGTTCAGCGACACCAATGGAGCTGTGA AATACTTCACAGTGGTGGTGAGAGAGGCTGATGGCAGTGATGAGCTGAAGCCAGAACAGCAGCACCCTCT CCCTTCCTACCTGGAGTACAGGCACAATGCCTCCATTCGGGTGTATCAGACTAATTATTTTGCCAGCAAA TGTGCCGAAAATCCTAACAGCAACTCCAAGAGTTTTAACATTAAGCTTGGAGCAGAGATGGAGAGCCTAG GTGGAAAATGCGATCCCACTCAGCAAAAATTCTGTGATGGACCACTGAAGCCACACACTGCCTACAGAAT CAGCATTCGAGCTTTTACACAGCTCTTTGATGAGGACCTGAAGGAATTCACAAAGCCACTCTATTCAGAC ACATTTTTTTCTTTACCCATCACTACTGAATCAGAGCCCTTGTTTGGAGCTATTGAAGGTGTGAGTGCTG GTCTGTTTTTAATTGGCATGCTAGTGGCTGTTGTTGCCTTATTGATCTGCAGACAGAAAGTGAGCCATGG TCGAGAAAGACCCTCTGCCCGTCTGAGCATTCGTAGGGATCGACCATTATCTGTCCACTTAAACCTGGGC CAGAAAGGTAACCGGAAAACTTCTTGTCCAATAAAAATAAATCAGTTTGAAGGGCATTTCATGAAGCTAC AGGCTGACTCCAACTACCTTCTATCCAAGGAATACGAGGAGTTAAAAGACGTGGGCCGAAACCAGTCATG TGACATTGCACTCTTGCCGGAGAATAGAGGGAAAAATCGATACAACAATATATTGCCCTATGATGCCACG CGAGTGAAGCTCTCCAATGTAGATGATGATCCTTGCTCTGACTACATCAATGCCAGCTACATCCCTGGCA ACAACTTCAGAAGAGAATACATTGTCACTCAGGGACCGCTTCCTGGCACCAAGGATGACTTCTGGAAAAT GGTGTGGGAACAAAACGTTCACAACATCGTCATGGTGACCCAGTGTGTTGAGAAGGGCCGAGTAAAGTGT GATCATTACTGGCCAGCGGACCAGGATTCCCTCTACTATGGGGACCTCATCCTGCAGATGCTCTCAGAGT CCGTCCTGCCTGAGTGGACCATCCGGGAGTTTAAGATATGCGGTGAGGAACAGCTTGATGCACACAGACT CATCCGCCACTTTCACTATACGGTGTGGCCAGACCATGGAGTCCCAGAAACCACCCAGTCTCTGATCCAG TTTGTGAGAACTGTCAGGGACTACATCAACAGAAGCCCGGGTGCTGGGCCCACTGTGGTGCACTGCAGTG CTGGTGTGGGTAGGACTGGAACCTTTATTGCATTGGACCGAATCCTCCAGCAGTTAGACTCCAAAGACTC TGTGGACATTTATGGAGCAGTGCACGACCTAAGACTTCACAGGGTTCACATGGTCCAGACTGAGTGTCAG TATGTCTACCTACATCAGTGTGTAAGAGATGTCCTCAGAGCAAGAAAGCTACGGAGTGAACAAGAAAACC CCTTGTTTCCAATCTATGAAAATGTGAATCCAGAGTATCACAGAGATCCAGTCTATTCAAGGCAT ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >RG226479 representing NM_001109754
Red=Cloning site Green=Tags(s) MEAEFYMVILTCLIFRNSEGFQIVHVQKQQCLFKNEKVVVGSCNRTIQNQQWMWTEDEKLLHVKSALCLA ISNSSRGPSRSAILDRCSQAPRWTCYDQEGFLEVENASLFLQKQGSRVVVKKARKYLHSWMKIDVNKEGK LVNESLCLQKAGLGAEVSVRSTRNTAPPQILTTFNAVPDGLVFLIRNTTEAFIRNAAENYSQNSSERQHP NLHMTGITDTSWVLSTTQPFSSTTEETGLAEPERCNFTLAESKASSHSVSIQWRILGSPCNFSLIYSSDT LGAALCPTFRIDNTTYGCNLQDLQAGTIYNFRIISLDEERTVVLQTDPLPPARFGVSKEKTTSTSLHVWW TPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGSTV PSPVKDIGISTKANSLLISWSHGSGNVERYRLMLMDKGILVHGGVVDKHATSYAFHGLTPGYLYNLTVMT EAAGLQNYRWKLVRTAPMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWITE THFKELVPGRLYQVTVSCVSGELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWEQYRILL FNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLKNSERCQGRTVPLAVLQLRVKHANETS LSIMWQTPVAEWEKYIISLADRDLLLIHKSLSKDAKEFTFTDLVPGRKYMATVTSISGDLKNSSSVKGRT VPAQVTDLHVANQGMTSSLFTNWTQAQGDVEFYQVLLIHENVVIKNESISSETSRYSFHSLKSGSLYSVV VTTVSGGISSRQVVVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAK SVRECSFSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSDYLRVSWVHATGDFDHY EVTIKNKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQYEANEQGNGRTIPEPVKDLTLRNRST EDLHVTWSGANGDVDQYEIQLLFNDMKVFPPFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFIE GFTVPSAVKNIHISPNGATDSLTVNWTPGGGDVDSYTVSAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQY QIMIASVSGSLKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDILLLTENGILLRNTS EPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITENSTRHLSFRWTASEGEL SWYNIFLYNPDGNLQERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGS NRNTTDSLWFNWSPASGDFDFYELILYNPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSGDLSNK VTAESRTAPSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRIVYGL RPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSIECRKM DTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDRPPPPPPHIRVNEKDV LISKSSINFTVNCSWFSDTNGAVKYFTVVVREADGSDELKPEQQHPLPSYLEYRHNASIRVYQTNYFASK CAENPNSNSKSFNIKLGAEMESLGGKCDPTQQKFCDGPLKPHTAYRISIRAFTQLFDEDLKEFTKPLYSD TFFSLPITTESEPLFGAIEGVSAGLFLIGMLVAVVALLICRQKVSHGRERPSARLSIRRDRPLSVHLNLG QKGNRKTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDAT RVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKC DHYWPADQDSLYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQ FVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQ YVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHRDPVYSRH TRTRPLE - GFP Tag - V |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001109754 |
| ORF Size | 6645 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001109754.4 |
| RefSeq Size | 11331 bp |
| RefSeq ORF | 6648 bp |
| Locus ID | 5787 |
| UniProt ID | P23467 |
| Protein Families | Druggable Genome, Phosphatase |
| Protein Pathways | Adherens junction |
| Gene Summary | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and one intracytoplasmic catalytic domain, thus belongs to receptor type PTP. The extracellular region of this PTP is composed of multiple fibronectin type_III repeats, which was shown to interact with neuronal receptor and cell adhesion molecules, such as contactin and tenascin C. This protein was also found to interact with sodium channels, and thus may regulate sodium channels by altering tyrosine phosphorylation status. The functions of the interaction partners of this protein implicate the roles of this PTP in cell adhesion, neurite growth, and neuronal differentiation. Alternate transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011] |
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