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ARNT2 (NM_014862) Human Untagged Clone
CAT＃: SC114814
ARNT2 (untagged)-Human aryl-hydrocarbon receptor nuclear translocator 2 (ARNT2)
CNY 5,256.00
货期*
现货
规格
| Cited in 2 publications. |
Product images
经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | bHLHe1; WEDAS |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC114814 sequence for NM_014862 edited (data generated by NextGen Sequencing)
ATGGCAACCCCGGCGGCGGTCAACCCTCCGGAAATGGCTTCAGACATACCTGGATCTGTG ACGTTGCCCGTTGCCCCCATGGCGGCCACCGGACAGGTGAGGATGGCGGGGGCCATGCCT GCCCGTGGAGGAAAGCGGCGTTCCGGAATGGACTTCGATGATGAAGATGGTGAAGGCCCC AGTAAATTTTCANNNGAGAATCATAGTGAAATCGAAAGGCGCAGACGGAACAAGATGACT CAGTACATCACGGAGCTCTCCGACATGGTCCCCACATGCAGCGCACTGGCTCGGAAGCCA GACAAGCTCACCATCCTCCGCATGGCCGTCTCGCACATGAAGTCCATGAGGGGTACAGGG AACAAGTCCACCGATGGCGCGTACAAGCCTTCCTTCCTCACAGAGCAGGAACTGAAGCAT CTCATCCTTGAAGCAGCTGATGGATTTCTGTTTGTGGTGGCTGCTGAGACAGGGCGAGTG ATTTATGTGTCTGACTCCGTCACCCCTGTTCTGAACCAGCCCCAGTCAGAGTGGTTTGGG AGCACACTGTATGAACAGGTGCATCCTGATGACGTGGAGAAGCTGAGAGAGCAACTGTGC ACCTCAGAAAACTCAATGACAGGCCGGATCTTGGACCTGAAGACTGGGACGGTCAAGAAA GAAGGGCAGCAGTCATCCATGAGGATGTGCATGGGCTCGCGGCGGTCTTTCATCTGCAGG ATGAGGTGTGGAAATGCTCCTTTGGACCACCTTCCTCTAAACAGAATAACCACCATGAGG AAAAGGTTCAGGAATGGCCTTGGCCCTGTGAAAGAAGGAGAAGCCCAATATGCTGTGGTC CACTGTACAGGATACATCAAGGCCTGGCCACCAGCAGGAATGACCATACCTGAAGAAGAC GCTGATGTGGGACAAGGCAGTAAATATTGCCTCGTGGCAATTGGGAGACTCCAGGTGACC AGCTCTCCTGTATGCATGGACATGAATGGGATGTCGGTGCCCACAGAGTTCTTATCCCGG CATAACTCCGATGGAATCATCACATTTGTGGATCCAAGATGTATCAGTGTGATTGGCTAC CAACCCCAGGATCTTCTGGGAAAGGACATTTTGGAATTCTGCCACCCTGAGGATCAAAGC CATCTGCGTGAGAGCTTCCAGCAGGTGGTTAAGCTGAAAGGCCAAGTCCTGTCGGTCATG TATCGATTTCGCACCAAGAACCGGGAGTGGATGTTGATCCGCACCAGCAGCTTCACATTC CAGAATCCCTATTCTGATGAGATTGAGTACATCATCTGCACCAACACCAACGTCAAGCAA CTTCAGCAACAGCAGGCAGAATTGGAAGTGCACCAGAGAGATGGATTGTCATCGTATGAC TTATCCCAGGTCCCCGTCCCCAACCTACCAGCCGGTGTTCATGAGGCCGGGAAGTCCGTG GAAAAGGCGGATGCAATCTTCTCCCAGGAAAGAGATCCTCGGTTTGCTGAAATGTTTGCA GGAATTAGTGCATCGGAGAAGAAGATGATGAGCTCAGCCTCTGCAGCAGGAACCCAGCAG ATCTACTCCCAAGGAAGCCCATTTCCCTCTGGACACTCCGGGAAGGCCTTCAGCTCTTCA GTGGTTCATGTGCCTGGAGTGAATGATATTCAGTCCTCTTCTTCCACGGGCCAGAACATG TCCCAAATCTCCCGGCAGCTAAACCAGAGTCAGGTGGCATGGACAGGGAGTCGTCCGCCC TTTCCGGGACAGCAAATCCCATCTCAGTCCAGCAAGACTCAGTCATCTCCCTTTGGGATT GGAACGAGCCACACCTACCCGGCAGACCCCTCTTCCTACAGCCCCCTCTCCAGCCCAGCT ACCTCCTCGCCAAGTGGGAATGCCTACTCCAGTCTTGCCAACAGGACTCCAGGGTTCGCT GAAAGTGGACAAAGTAGCGGGCAGTTCCAAGGGCGGCCCTCGGAAGTCTGGTCGCAGTGG CAAAGCCAGCACCATGGCCAGCAGAGCGGTGAGCAGCACTCCCACCAGCAGCCCGGTCAG ACTGAAGTGTTCCAGGACATGCTGCCCATGCCAGGAGATCCAACCCAGGGGACTGGCAAC TATAACATCGAAGACTTTGCCGACCTGGGCATGTTTCCACCGTTTTCTGAGTAG Clone variation with respect to NM_014862.3 193 a=>n;194 g=>n;195 a=>n >OriGene 5' read for NM_014862 unedited
GTAACGTTCCAATTTGTATACGACTCATATAGGCGGCCGCGAATTCGCACGAGGGGAGCG CCGCCCGCCCGCGCCGTCCTTTGTGTGGCGGCGGCGGCGCCTGGTCCTGACCGGGTCCCC GGGGCTGAGCGCCGGGCTCCGCGCCGCCCCTCCCGCGCCCCTGCCAAGCGGGCGCCTATC CTCTCCGAGCAAGATGGCAACCCCGGCGGCGGTCAACCCTCCGGAAATGGCTTCAGACAT ACCTGGATCTGTGACGTTGCCCGTTGCCCCCATGGCGGCCACCGGACAGGTGAGGATGGC GGGGGCCATGCCTGCCCGTGGAGGAAAGCGGCGTTCCGGAATGGACTTCGATGATGAAGA TGGTGAAGGCCCCAGTAAATTTTCAAGAGAATCATAGTGAAATCGAAAGGCGCAGACGGA ACAAGATGACTCAGTACATCACGGAGCTCTCCGACATGGTCCCCACATGCAGCGCACTGG CTCGGAAGCCAGACAAGCTCACCATCCTCCGCATGGCCGTCTCGCACATGAAGTCCATGA GGGGTACAGGGAACAAGTCCACCGATGGCGCGTACAAGCCTTCCTTCCTCACAGAGCAGG AACTGAAGCATCTCATCCTTGAAGCAGCTGATGGATTTCTGTTTGTGGTGGCTGCTGAGA CAGGGCGAGTGATTTATGTGTCTGACTCCGTCACCCCTGTTCTGAACCAGCCCCAGTCAG AGTGGTTTGGGAGCACACTGTATGAACAGGTGCATCCTGATGACGTGGAGAAGCTGAGAG AGCAACTGTGCACCTCAGATAACTCAATGACAGGCCGGATCTTGGACCTGAAGACTGGGA CGGTCAAGATAGAATGGCAGCAGTCATCCATGAAGATGTGCATGGGCTCGCGGCGGTC >OriGene 3' read for NM_014862 unedited
ATGTACGCGGCCGCATCTATAGTCGGTTTTTTTTTTTTTTTTTTAAAGGAAACTGAGATT GTTAGATGAAGCAAGCCGTCCTGCTCCCGCACAGCCTGTGAAACCTCCATTTTGCCACTT TCAAGGTCAGTGCCCCACAGACCCTGGCCTGTTGTTGACCATAACACTAGCTTTGGCCAC AAAAGCCAGGGACACCTACGCTTGGAAATGTGCCTGCACCACTGTGTGGTGCCTCCTTAA GTTGCCCCACACTCCACATGGCCAAAGAAAAGGTGAATGTCCAGGTGGTTTATTGGCTTC TTATTATGGGGTGTTTGGTGGGGAATGACCCCGGTAGGTTAGGAGACAGTGACTTAGGTC AAGTCCATATTTTCTGGTTTTATAAAGGACACTCGTATTCTGACTTGCGATTTCTATAGC TGTAAGGGTTACTGTCTGTTTACTGTTATATGTGGTTCGCTATAACCGTCACGGTATTAG GTGAGTGCTCCATTGTTATGTTCCTTATGGACTCTTTAAGTGCCGTCCTCAGTGGTCAGA CTATTTCTTTATTTGAATATGTTGTCTTTTTTGTTTTTGCCCTTAAGTCTTCATGTTATT CTGTATTCATCGCATCCCGTAATCACATCTAAATATCTTCTCCTCTTCTNCTCACTTCTC TCTCTCTCTTATCACCTCGATTTCGCCCCTCACCTCTTCCTTCCTTCTGCTATTTCTCCA TATGCTCTCTCCTTCATCTCTCTATGTGTTCTCCCCTCTTTGCCCTTCATTTCGCTTCCC CCTTCTTCTTCTTCCTCATCTTCTCTTTATTCTTCTTCTGCACCCCTCGCTCCNCACTAT CTTACTCTTTCCTCTTCCTAATTCTTTTTTCACACTCACCCTCCTCTACTTCTCTCTCTC TTGTCCTGATCTTGTCATCCTATTAGTGATTCCTCATCTTATCATTTCCTACCTTCGATT CTAATCTACCTACACCCCCTCCTCTTCGAC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_014862 |
| Insert Size | 6930 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_014862.3, NP_055677.3 |
| RefSeq Size | 6576 bp |
| RefSeq ORF | 2154 bp |
| Locus ID | 9915 |
| UniProt ID | Q9HBZ2 |
| Domains | PAS, HLH, PAC |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | Pathways in cancer, Renal cell carcinoma |
| Gene Summary | This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting additional roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively. [provided by RefSeq, Dec 2013] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Mutation screen of the SIM1 gene in pediatric patients with early-onset obesity
,Zegers, D;Beckers, S;Hendrickx, R;Van Camp, JK;de Craemer, V;Verrijken, A;Van Hoorenbeeck, K;Verhulst, SL;Rooman, RP;Desager, KN;Massa, G;Van Gaal, LF;Van Hul, W;,
Int J Obes (Lond). 2013 Oct 7.
,PubMed ID 24097297
[ARNT2]
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Analysis of the SIM1 Contribution to Polygenic Obesity in the French Population
,Maya Ghoussaini, Fanny Stutzmann, Cyril Couturier, Vincent Vatin, Emmanuelle Durand, Cécile Lecoeur, Franck Degraeve, Barbara Heude, Maithé Tauber, Serge Hercberg, et al.,
Obesity (14 January 2010) doi:10.1038/oby.2009.468 Genetics
[ARNT2]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211966 | ARNT2 (Myc-DDK-tagged)-Human aryl-hydrocarbon receptor nuclear translocator 2 (ARNT2) |
CNY 5,256.00 |
|
| RC211966L3 | Lenti ORF clone of Human aryl-hydrocarbon receptor nuclear translocator 2 (ARNT2), Myc-DDK-tagged |
CNY 7,700.00 |
|
| RC211966L4 | Lenti ORF clone of Human aryl-hydrocarbon receptor nuclear translocator 2 (ARNT2), mGFP tagged |
CNY 7,700.00 |
|
| RG211966 | ARNT2 (tGFP-tagged) - Human aryl-hydrocarbon receptor nuclear translocator 2 (ARNT2) |
CNY 6,370.00 |
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