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RRAS (NM_006270) Human Untagged Clone
CAT＃: SC116180
RRAS (untagged)-Human related RAS viral (r-ras) oncogene homolog (RRAS)
CNY 2,400.00
CNY 2,950.00
| Cited in 2 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | R-Ras |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC116180 sequence for NM_006270 edited (data generated by NextGen Sequencing)
ATGAGCAGCGGGGCGGCGTCCGGGACAGGGCGGGGGCGGCCCCGGGGCGGGGGACCTGGG CCCGGGGACCCCCCGCCCAGCGAGACACACAAGCTGGTGGTCGTGGGCGGCGGCGGCGTG GGCAAGAGCGCGCTGACCATCCAGTTCATCCAGTCCTACTTCGTGTCTGACTACGACCCC ACTATTGAGGACTCCTACACGAAGATCTGCAGTGTGGATGGCATCCCAGCCCGGCTGGAC ATCCTGGACACCGCGGGCCAGGAAGAGTTCGGGGCCATGAGAGAGCAGTACATGCGTGCT GGCCACGGCTTCCTGCTGGTGTTCGCCATTAATGACCGGCAGAGTTTCAACGAGGTGGGC AAGCTCTTCACGCAGATTCTGCGGGTCAAGGACCGCGACGACTTCCCCGTTGTGTTGGTC GGGAACAAGGCAGATCTGGAGTCACAGCGCCAGGTCCCCCGATCAGAAGCCTCTGCCTTC GGCGCCTCCCACCACGTGGCCTACTTTGAGGCCTCGGCCAAACTGCGTCTCAACGTGGAC GAGGCTTTTGAGCAGCTGGTGCGGGCTGTCCGGAAATACCAGGAACAAGAGCTCCCACCG AGCCCTCCCAGTGCCCCCAGGAAGAAGGGCGGGGGCTGCCCCTGCGTCCTCCTGTAG Clone variation with respect to NM_006270.3 333 c=>t >OriGene 5' read for NM_006270 unedited
TTGGATTTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACCAGGCGGTGGCGACA TGAGCAGCGGGGCGGCGTCCGGGACAGGGCGGGGGCGGCCCCGGGGCGGGGGACCTGGGC CCGGGGACCCCCCGCCCAGCGAGACACACAAGCTGGTGGTCGTGGGCGGCGGCGGCGTGG GCAAGAGCGCGCTGACCATCCAGTTCATCCAGTCCTACTTCGTGTCTGACTACGACCCCA CTATTGAGGACTCCTACACGAAGATCTGCAGTGTGGATGGCATCCCAGCCCGGCTGGACA TCCTGGACACCGCGGGCCAGGAAGAGTTCGGGGCCATGAGAGAGCAGTACATGCGTGCTG GCCACGGCTTCCTGCTGGTGTTCGCCATTAATGACCGGCAGAGTTTCAACGAGGTGGGCA AGCTCTTCACGCAGATTCTGCGGGTCAAGGACCGCGACGACTTCCCCGTTGTGTTGGTCG GGAACAAGGCAGATCTGGAGTCACAGCGCCAGGTCCCCCGATCAGAAGCCTCTGCCTTCG GCGCCTCCCACCACGTGGCCTACTTTGAGGCCTCGGCCAAACTGCGTCTCAACGTGGACG AGGCTTTTGAGCAGCTGGTGCGGGCTGTCCGGAAATACCAGGAACAAGAGCTCCCACCGA GCCCTCCCAGTGCCCCCAGGAAGAAGGGCGGNGGCTGCCCCTGCGTCCTCCTGTAGCCCA GGCAAGAGAGAAGCAACCACCACAAGCTCTCGGGACTAGCTGCCTTCGCACCTTGCTGTG TGACCTGAGGCCCTCACTGAGCCTCAATTTTCTCATCTGGGTCTCCCAGGACACATCACA TACCCACCTTTACTTNCTGGCCTCTNCTGGGCTACTGCCACTGTGTGCCTTCTGCCAACG CCTCCTGTCCCCACCTAACCTGTGGNGGGTGAGGGGCTCCCGGTCACTGCTGAATTAACT CCCCTNCCCAGAAATAAAT >OriGene 3' read for NM_006270 unedited
TTTTTTTTTGACGTTGGCAGTGACATTTATTTTTCTGGGGGAGGGGAGTTATATACAGCA GTGACCCGGAGCCCCTCACCCCCACCAGGCTTAGGTGGGGACAGGAGGCGTTGGCAGAAG GCACACAGTGGCAGTAGCCCAGAAGAGGCCAGGAAGTAAGGGTGGGTATGTGATGTGTCC TGGGAGACCCAGATGAGGAAATTGAGGCTCAGTGAGGGCCTCAGGTCACACAACAAGGTG CGAAGGCAGCTAGTCCCGAGAGCTTGTGGTGGTTGCTTCTCTCTTGCCTGGGCTACAGGA GGACGCAGGGGCAGCCCCCGCCCTTCTTCCTGGGGGCACTGGGAGGGCTCGGTGGGAGCT CTTGTTCCTGGTATTTCCGGACAGCCCGCACCAGCTGCTCAAAAGCCTCGTCCACGTTGA GACGCAGTTTGGCCGAGGCCTCAAAGTAGGCCACGTGGTGGGAGGCGCCGAAGGCAGAGG CTTCTGATCGGGGGACCTGGCGCTGTGACTCCAGATCTGCCTTGTTCCCGACCAACACAA CGGGGAAGTCGTCGCGGTCCTTGACCCGCAGAATCTGCGTGAAGAGCTTGCCCACCTCGT TGAAACTCTGCCGGTCATTAATGGCGAACACCAGCAGGAAGCCGTGGCCAGCACGCATGT AC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_006270 |
| Insert Size | 1100 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_006270.2, NP_006261.1 |
| RefSeq Size | 1017 bp |
| RefSeq ORF | 657 bp |
| Locus ID | 6237 |
| UniProt ID | P10301 |
| Domains | ras, RAN, RAS, RHO, RAB |
| Protein Families | Druggable Genome |
| Protein Pathways | MAPK signaling pathway, Regulation of actin cytoskeleton, Tight junction |
| Gene Summary | The protein encoded by this gene is a small GTPase involved in diverse processes including angiogenesis, vascular homeostasis and regeneration, cell adhesion, and neuronal axon guidance. Mutations in this gene are found in many invasive cancers. [provided by RefSeq, Jul 2015] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
MiR-124 governs glioma growth and angiogenesis and enhances chemosensitivity by targeting R-Ras and N-Ras
,null,
Neuro-Oncology
,PubMed ID 24861879
[RRAS]
|
|
Funktionelle Charakterisierung von humanen CBL-und RRAS-Proteinvarianten fu¨r ein besseres Versta¨ndnis der Pathophysiologie bei RASopathien
,Brand, K;,
Thesis
[RRAS]
|
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Resources
Other Versions
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| RC204820L2 | Lenti ORF clone of Human related RAS viral (r-ras) oncogene homolog (RRAS), mGFP tagged |
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| RC204820L3 | Lenti ORF clone of Human related RAS viral (r-ras) oncogene homolog (RRAS), Myc-DDK-tagged |
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| RC204820L4 | Lenti ORF clone of Human related RAS viral (r-ras) oncogene homolog (RRAS), mGFP tagged |
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| RG204820 | RRAS (tGFP-tagged) - Human related RAS viral (r-ras) oncogene homolog (RRAS) |
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