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CDK5 (NM_004935) Human Untagged Clone
CAT＃: SC117039
CDK5 (untagged)-Human cyclin-dependent kinase 5 (CDK5), transcript variant 1
CNY 3,600.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | LIS7; PSSALRE |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_004935 edited
ATGCAGAAATACGAGAAACTGGAAAAGATTGGGGAAGGCACCTACGGAACTGTGTTCAAG GCCAAAAACCGGGAGACTCATGAGATCGTGGCTCTGAAACGGGTGAGGCTGGATGACGAT GATGAGGGTGTGCCGAGTTCCGCCCTCCGGGAGATCTGCCTACTCAAGGAGCTGAAGCAC AAGAACATCGTCAGGCTTCATGACGTCCTGCACAGCGACAAGAAGCTGACTTTGGTTTTT GAATTCTGTGACCAGGACCTGAAGAAGTATTTTGACAGTTGCAATGGTGACCTCGATCCT GAGATTGTAAAGTCATTCCTCTTCCAGCTACTAAAAGGGCTGGGATTCTGTCATAGCCGC AATGTGCTACACAGGGACCTGAAGCCCCAGAACCTGCTAATAAACAGGAATGGGGAGCTG AAATTGGCTGATTTTGGCCTGGCTCGAGCCTTTGGGATTCCCGTCCGCTGTTACTCAGCT GAGGTGGTCACACTGTGGTACCGCCCACCGGATGTCCTCTTTGGGGCCAAGCTGTACTCC ACGTCCATCGACATGTGGTCAGCCGGCTGCATCTTTGCAGAGCTGGCCAATGCTGGGCGG CCTCTTTTTCCCGGCAATGATGTCGATGACCAGTTGAAGAGGATCTTCCGACTGCTGGGG ACGCCCACCGAGGAGCAGTGGCCCTCTATGACCAAGCTGCCAGACTATAAGCCCTATCCG ATGTACCCGGCCACAACATCCCTGGTGAACGTCGTGCCCAAACTCAATGCCACAGGGAGG GATCTGCTGCAGAACCTTCTGAAGTGTAACCCTGTCCAGCGTATCTCAGCAGAAGAGGCC CTGCAGCACCCCTACTTCTCCGACTTCTGTCCGCCCTAG >OriGene 5' read for NM_004935 unedited
NGGTCAAATTTTGTATACGACTCCTATAGGGCGGCCGCGAATTCGCACGAGGCGCAGGGG TCCCCGCGGCCGCCGCGAGCAGAATACGAGAACTGGAAAAGATGGGGAAGGCACCTACGG AACTGTGTTCAAGGCCAAAAACCGGGAGACTCATGAGATCGTGGCTCTGAAACGGGTGAG GCTGGATGACGATGATGAGGGTGTGCCGAGTTCCGCCCTCCGGGAGATCTGCCTACTCAA GGAGCTGAAGCACAAGAACATCGTCAGGCTTCATGACGTCCTGCACAGCGACAAGAAGCT GACTTTGGTTTTTGAATTCTGTGACCAGGACCTGAAGAAGTATTTTGACAGTTGCAATGG TGACCTCGATCCTGAGATTGTAAAGTCATTCCTCTTCCAGCTACTAAAAGGGCTGGGATT CTGTCATAGCCGCAATGTGCTACACAGGGACCTGAAGCCCCAGAACCTGCTAATAAACAG GAATGGGGAGCTGAAATTGGCTGATTTTGGCCTGGCTCGAGCCTTTGGGATTCCCGTCCG CTGTTACTCAGCTGAGGTGGTCACACTGTGGTACCGCCCACCGGATGTCCTCTTTGGGGC CAAGCTGTACTCCACGTCCATCGACATGTGGTCAGCCGGCTGCATCTTTGCAGAGCTGGC CAATGCTGGGCGGCCTCTTTTTCCCGGCAATGATGTCGATGACCAGTTGAAGAGGATCTT CCGACTGCTGGGGACGCCCACCGAGGAGCAGTGGCCCTCTATGACCAAGCTGCCAGACTA TAAGCCCTATCCGATGTACCCGGCCACACATCCCTGGTGAACGTCGTGCCCAAACTCATG CCACAGGNAGGGATCTGCTGCAGAACCTTCTGAGTGTAACCCTGC >OriGene 3' read for NM_004935 unedited
TATGGACCGGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTGTGGGAAAGGA GCCAATTTATGAAATTAAATAAAGTCCACAAAGGGGAGTGGAGAAATTCGGNGCTCAGGG CACCCCACACCCGGCGTGGGGCCCAGCACCTGCTTGGAGCACAGACGCACCAGAGCACCC CCCACTTGTCTCACACCCTCTCAAGAGGGGGCCTTAAATAGGCCAGAGCCCCAGCCCTGG AGGCCGGGGGGTCCCGGGGNCCTAGGGGCGGACACGAAGTCGNGAGAAGTAGGGGTGCGT GCAGGGCCCTCTTCTGCTGAGATACGCTGGACAGGGTTACACTTCAGAAGGTTCTGCAGC AGATCCCTCCCTGTGGCATTGAGTTTGGGCACGACGTTCACCAGGGATGTTGTGGCCGGG TACATCGGATAGGGCTTATAGTCTGGCAGCTTGGTCATAGAGGGCCACTGCTCCTCGGTG GGCGTCCCCAGCAGTCGGAAGATCCTCTTCAACTGGTCATCGACATCATTGCCGGGAAAA AGAGGCCGCCCAGCATTGGCCAGCTCTGCAAAGATGCAGCCGGCTGACCACATGTCGATG GACGTGGAGTACAGCTTGGCCCCAAAGAGGACATCCGGTGGGCGGTACCACAGTGTGACC ACCTCAGCTGAGTAACAGCGGACGGGAATCCCAAGGCTCGAGCCAGGCCAAAATCAGCCA ATTTCAGCTCCCCATTCCTGCTTATTAGCCGGTTCCTGGGCCTCAGGTCCCTGTGTAGCC ACATGCGGCTATGACAGAATCCCACCCCTTTTAGTACCTGGAAGAGCATGACCTTACAAT CTCAGATCGAGGTCCCATTGCAACTGGCAAATACCTCTTCAGTCCCTGGTCCAGAATTCA AAACCAAGTCCCTTCTTGCCCTGTGCAGGACTCCTGAAGCTGCCAC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004935 |
| Insert Size | 1200 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_004935.2, NP_004926.1 |
| RefSeq Size | 1143 bp |
| RefSeq ORF | 879 bp |
| Locus ID | 1020 |
| UniProt ID | Q00535 |
| Domains | pkinase, TyrKc, S_TKc |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | Alzheimer's disease, Axon guidance |
| Gene Summary | This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200342 | CDK5 (Myc-DDK-tagged)-Human cyclin-dependent kinase 5 (CDK5), transcript variant 1 |
CNY 3,600.00 |
|
| RC200342L1 | Lenti ORF clone of Human cyclin-dependent kinase 5 (CDK5), transcript variant 1, Myc-DDK-tagged |
CNY 6,000.00 |
|
| RC200342L2 | Lenti ORF clone of Human cyclin-dependent kinase 5 (CDK5), transcript variant 1, mGFP tagged |
CNY 6,000.00 |
|
| RC200342L3 | Lenti ORF clone of Human cyclin-dependent kinase 5 (CDK5), transcript variant 1, Myc-DDK-tagged |
CNY 6,000.00 |
|
| RC200342L4 | Lenti ORF clone of Human cyclin-dependent kinase 5 (CDK5), transcript variant 1, mGFP tagged |
CNY 6,000.00 |
|
| RG200342 | CDK5 (tGFP-tagged) - Human cyclin-dependent kinase 5 (CDK5), transcript variant 1 |
CNY 5,200.00 |
|
| SC323541 | CDK5 (untagged)-Kinase deficient mutant (K33M) of Human cyclin-dependent kinase 5 (CDK5) |
CNY 3,600.00 |
