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HPS2 (AP3B1) (NM_003664) Human Untagged Clone
CAT＃: SC117848
AP3B1 (untagged)-Human adaptor-related protein complex 3, beta 1 subunit (AP3B1)
CNY 7,624.00
货期*
现货
规格
| Cited in 1 publication. |
Product images
经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ADTB3; ADTB3A; HPS; HPS2; PE |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC117848 sequence for NM_003664 edited (data generated by NextGen Sequencing)
ATGTCCAGCAATAGTTTTCCTTACAATGAGCAGTCCGGAGGAGGGGAGGCGACGGAGCTG GGTCAGGAGGCGACCTCAACCATTTCCCCCTCGGGGGCCTTCGGCCTCTTTAGCAGCGAT TTGAAGAAGAATGAAGATCTAAAGCAAATGTTAGAGAGCAACAAAGATTCTGCTAAACTG GATGCTATGAAGCGGATTGTTGGGATGATTGCAAAAGGGAAAAATGCATCTGAACTGTTT CCTGCTGTTGTGAAGAATGTGGCCAGTAAAAATATTGAGATCAAGAAGTTGGTATATGTT TACCTGGTTCGATATGCTGAAGAACAGCAGGATCTTGCACTCCTGTCCATAAGCACTTTT CAGCGAGCTCTGAAGGACCCAAACCAACTAATTCGTGCAAGCGCTTTGAGAGTTCTGTCA AGTATTAGAGTGCCAATTATTGTACCTATCATGATGCTTGCTATTAAGGAAGCTTCTGCT GACTTATCACCATATGTTAGGAAGAATGCAGCCCATGCAATACAAAAATTATACAGCCTT GATCCAGAGCAGAAGGAAATGTTAATTGAAGTAATTGAAAAACTTCTGAAAGATAAAAGC ACATTGGTAGCTGGCAGTGTTGTGATGGCTTTTGAAGAAGTATGCCCGGACAGAATAGAT CTGATTCATAAAAATTACCGCAAGCTATGTAACTTACTAGTGGATGTTGAAGAGTGGGGG CAGGTTGTCATAATCCACATGCTAACTCGATATGCTCGGACACAGTTTGTCAGCCCTTGG AAAGAGGGTGATGAATTAGAAGACAATGGAAAGAATTTCTACGAATCTGATGATGATCAG AAGGAAAAGACTGACAAAAAGAAGAAGCCGTATACTATGGATCCAGATCATAGACTCTTA ATTAGAAATACAAAGCCTTTGCTTCAGAGCAGGAATGCTGCGGTGGTTATGGCAGTTGCT CAGCTGTATTGGCACATATCACCAAAATCTGAAGCTGGCATAATTTCTAAATCACTAGTG CGTTTACTTCGTAGCAATAGGGAGGTGCAGTATATTGTCCTACAAAATRTAGCAACTATG TCAATTCAAAGAAAGGGGATGTTTGAACCTTATCTGAAGAGTTTCTATGTTAGGTCAACT GATCCAACTATGATCAAGACACTGAAGCTTGAAATTTTGACAAACTTGGCAAATGAAGCC AACATATCAACTCTTCTTCGAGAATTTCAGACCTATGTGAAAAGCCAGGATAAACAATTT GCAGCAGCCACTATTCAGACTATAGGCAGATGTGCAACCAACATCTTGGAAGTCACTGAC ACGTGCCTCAATGGCTTGGTCTGTCTGCTGTCCAACAGGGATGAAATAGTTGTTGCTGAA AGTGTGGTTGTTATAAAGAAATTACTGCAAATGCAACCTGCACAACATGGTGAAATTATT AAACATATGGCCAAACTCCTGGACAGTATCACTGTTCCTGTTGCTAGAGCAAGTATTCTT TGGCTAATTGGAGAAAACTGTGAACGAGTTCCTAAAATTGCCCCTGATGTTTTGAGGAAG ATGGCTAAAAGCTTCACTAGTGAAGATGATCTGGTAAAACTGCAGATATTAAATCTGGGA GCAAAATTGTATTTAACCAACTCCAAACAGACAAAATTGCTTACCCAGTACATATTAAAT CTCGGCAAGTATGATCAAAACTACGACATCAGAGACCGTACAAGATTTATTAGGCAGCTT ATTGTTCCGAATGAAAAGAGTGGAGCTTTAAGTAAATATGCCAAAAAAATATTCCTAGCA CAAAAGCCTGCACCACTGCTTGAGTCTCCTTTTAAAGATAGAGATCATTTCCAGCTTGGC ACCTTATCTCATACTCTCAACATTAAAGCTACTGGGTACCTGGAATTATCTAATTGGCCA GAGGTGGCGCCCGACCCATCAGTTCGAAATGTAGAAGTAATAGAGTTGGCAAAAGAATGG ACCCCAGCAGGAAAAGCAAAGCAAGAGAATTCTGCTAAGAAGTTTTATTCTGAATCTGAG GAAGAGGAGGACTCTTCTGATAGTAGCAGTGACAGTGAGAGTGAATCTGGAAGTGAAAGT GGAGAACAAGGCGAAAGTGGGGAGGAAGGAGACAGCAATGAGGACAGCAGTGAGGACTCC TCCAGTGAGCAGGACAGTGAGAGTGGACGGGAGTCAGGCCTAGAAAACAAAAGAACAGCC AAGAGGAACTCAAAAGCCAAAGGAAAAAGTGATTCTGAAGATGGGGAGAAGGAAAATGAA AAATCTAAAACTTCAGATTCTTCAAATGACGAATCTAGTTCAATAGAAGACAGTTCTTCC GATTCTGAATCAGAGTCAGAACCTGAAAGTGAATCTGAATCCAGAAGAGTCACTAAGGAG AAAGAAAAGAAAACAAAGCAAGATAGAACTCCTCTTACCAAAGATGTTTCACTTCTAGAT CTGGATGATTTTAACCCAGTATCCACTCCAGTTGCACTTCCCACACCAGCTCTTTCTCCA AGTTTGATGGCTGATCTTGAAGGTTTACACTTGTCAACTTCCTCTTCAGTCATCAGTGTC AGTACTCCTGCATTTGTACCAACGAAAACTCACGTGCTGCTTCATCGAATGAGTGGAAAA GGACTAGCTGCCCATTATTTCTTTCCAAGACAGCCTTGCATTTTTGGTGATAAGATGGTC TCTATACAAATAACACTGAATAACACTACTGATCGAAAGATAGAAAATATCCACATAGGG GAAAAAAAACTTCCTATAGGCATGAAAATGCATGTTTTTAATCCAATAGACTCTCTTGAG CCTGAGGGATCCATTACAGTTTCAATGGGTATTGACTTTTGTGATTCTACTCAGACTGCC AGTTTCCAGTTGTGTACCAAGGATGATTGCTTCAATGTTAATATTCAGCCACCTGTTGGA GAACTGCTTTTACCTGTGGCCATGTCAGAGAAAGATTTTAAGAAAGAGCAAGGAGTGCTA ACAGGAATGAATGAAACTTCTGCTGTAATCATTGCTGCACCACAGAATTTCACTCCCTCT GTGATCTTTCAGAAGGTTGTAAATGTAGCCAATGTAGGTGCAGTCCCTTCTGGCCAGGAT AATATACACAGGTTTGCAGCTAAAACTGTGCACAGTGGGTCATTGATGCTAGTCACAGTG GAACTGAAGGAAGGCTCTACAGCCCAGCTTATCATAAACACTGAGAAAACTGTGATTGGC TCTGTTCTGCTGCGGGAACTGAAGCCTGTCCTGTCTCAGGGGTAA Clone variation with respect to NM_003664.3 1069 a=>r;1754 t=>a >OriGene 5' read for NM_003664 unedited
NGGGGGAAANNGGGAAACGACTCCTATAGGGCGGCCGCGAATCGGCACGAGGGCCAGGNC GGCTCAGGGAGCCGTGACGAGTCCGGCAGCGCCTGCGCGCGCTCCTCCGTACGAGAACTA GTTTTGTTCCGTGCCCTCTGGACTGGAACCTTTTGGAGAGAACCCCCGGCAGGACCAACC CCGCACCCGCCAGCACCGCGGCAATGTCCAGCAATAGTTTTCCTTACAATGAGCAGTCCG GAGGAGGGGAGGCGACGGAGCTGGGTCAGGAGGCGACCTCAACCATTTCCCCCTCGGGGG CCTTCGGCCTCTTTAGCAGCGATTTGAAGAACAATGAAGATCTAAAGCACATGTTAGAGA GCAACAAAGATTCTGCTAAACTGGATGCTATGAAGCGGATTGTTGGGATGAATGCAAAAG GGAAAAATGCATCTGAACCTGTTTCCTGCTGCTGTGAAGAATGTGGCCAGTAAAAATATT GAGATCAAGAAGTTGGTATATGTCTACCTGCTTCGATATGCTGAACAACAGCACGATCTT GCACTCCCTGTCCATAACCCCTTTTCAGCGAGCTCTGAAGGACCCAAACCAACTAATCTC TGCAAGCGCTTTGAGAGTTCTGTCAAGTATTACAGCGCCAATTATTGTACCTATCATGAT GCTTTGTATTAAAGAAGCTTTTGCTGACTTATCACCATATGTTAGGAAGAATGCAGCCCA TGCCATAACAAAATTATACCGTCTTGATCCATACCAGAAGGAAATGTTTATTGAAGTAAT TGAAAAACTTCTCGAAGATAAAAGCCCATCGCTAGCTGGCACTGTTGTGAACGCGCTTCG CAACATAATGCCCCGTCCCGATATATTCCCTTTCTTAAAACTACCCGCCAGCTATGTAAC TTACTATTGGAGGTTGAAAAG >OriGene 3' read for NM_003664 unedited
NNTTTTTACTCTGGNACCGCGGCCGCAANCTAGGATCGAGTTTTTTTTTTTTTTTTTTGA TTCATATGCTAGTTTATTTATCTTATTATTGAGAGATAATTTCATGATGACAGTTATCAA TAATCAATTACAATATCAAGAAATTCAAAGAACAAAATCTTGCAGAGACTATGCTTTTGT ATTTGGATTTAAAAAGTATGTGATCTCATTTTCACATACCAAGCTGAGAGGCCATTTAGA CTATCTCTTTGCTAATTTTTGCTTACTGCTGTAGGGAAGAAGATTTCCAATGAACTTTAA ATATCTCATTCATGTCTACCATTGTCGAAAAAGAGAAGGAAAACGAGGAGGCCAAAAGAA GCAGCAGGACAGAGAAAACGCCACATGGATTCAAGAGTTGAGACAACTGACAGTAAAATA TATGCTCTTTGGTTAGCAAAGCAAAAAGGGGGAAAGTATTGCATACATGATAGATACACA CTAGCATTCTAAAGCAGGAGACAAGAATGTCAAGAGTGTATTCTTCCCCCCACTGCCAGA TGGAAGGGCTATTATTATAAATGAAAGGCAGCAGTAGTGGATGCCAGGCACTTTTGTTGT GTGCCAGATTCTAAAGTCCAGATGTAAGCAGGTTACCCCTGAGACAGGACAGGCTTTAGT TCCCGCAGCAGAACAGAGGCAATCACAGGTTTTCTCAGTGTTTATGATACGCTGGGCTGA AGAGCCCTCCTTTTAGTTCCACTGTGACTAGCATACATGACCCCCTGTGCACCAGTTTAG CTGCAAACCTGGGTTTATTATCCTTGGCCAGAGGGACTGCCCCTACATTGGCTACATTTA CAACCTTCTGAAAGACCCAGAGGAAGTGAATTTTGGGTGGACCATGATTACCACAAATTT TTTTCTTCCTGT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003664 |
| Insert Size | 4200 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_003664.3, NP_003655.3 |
| RefSeq Size | 4009 bp |
| RefSeq ORF | 3285 bp |
| Locus ID | 8546 |
| UniProt ID | O00203 |
| Domains | Adaptin_N |
| Protein Pathways | Lysosome |
| Gene Summary | This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2012] Transcript Variant: This variant (1) encodes the longer isoform (1). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Defective HIV-1 Particle Assembly in AP-3-Deficient Cells Derived from Patients with Hermansky-Pudlak Syndrome Type 2
,Ling Liu, Jessica Sutton, Elvin Woodruff, Fernando Villalta, Paul Spearman, and Xinhong Dong,
J. Virol., Oct 2012; 86: 11242 - 11253.
[AP3B1]
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| RG207124 | AP3B1 (tGFP-tagged) - Human adaptor-related protein complex 3, beta 1 subunit (AP3B1) |
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