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KCNA3 (NM_002232) Human Untagged Clone
CAT＃: SC118765
KCNA3 (untagged)-Human potassium voltage-gated channel, shaker-related subfamily, member 3 (KCNA3)
CNY 5,848.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HGK5; HLK3; HPCN3; HUKIII; KV1.3; MK3; PCN3 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_002232 edited
ATGGACGAGCGCCTCAGCCTTCTGCGCTCGCCGCCGCCGCCCTCAGCCCGCCACCGCGCC CACCCTCCTCAGCGCCCAGCGAGCAGCGGCGGTGCCCACACGCTGGTGAACCACGGCTAC GCGGAGCCCGCCGCAGGCCGCGAGCTGCCGCCCGACATGACCGTGGTGCCCGGGGACCAC CTGCTGGAGCCGGAGGTGGCCGATGGTGGAGGGGCCCCGCCTCAAGGCGGCTGTGGCGGC GGCGGCTGCGACCGCTACGAGCCGCTGCCGCCCTCACTGCCGGCCGCGGGCGAGCAGGAC TGCTGCGGGGAGCGCGTGGTCATCAACATCTCCGGGCTGCGCTTCGAGACGCAGCTGAAG ACCCTTTGCCAGTTCCCCGAGACGCTGCTGGGCGACCCCAAGCGGCGCATGAGGTACTTC GACCCGCTCCGCAACGAGTACTTCTTCGACCGCAACCGGCCCAGCTTCGACGCCATCCTC TACTACTATCAGTCCGGGGGCCGCATCCGCCGGCCGGTCAACGTGCCCATCGACATTTTC TCCGAGGAGATCCGCTTCTACCAGCTGGGCGAGGAGGCCATGGAGAAGTTCCGCGAGGAC GAGGGCTTCCTGCGGGAGGAGGAGCGGCCCTTGCCCCGCCGCGACTTCCAGCGCCAGGTG TGGCTGCTCTTCGAGTACCCCGAGAGCTCCGGGCCGGCCCGGGGCATCGCCATCGTGTCC GTGCTGGTCATCCTCATCTCCATTGTCATCTTCTGCCTGGAGACGCTGCCGGAGTTCCGC GACGAGAAGGACTACCCCGCCTCGACGTCGCAGGACTCATTCGAAGCAGCCGGCAACAGC ACGTCGGGGTCCCGCGCAGGAGCCTCCAGCTTCTCCGATCCCTTCTTCGTGGTGGAGACG CTGTGCATCATCTGGTTCTCCTTCGAACTGCTGGTGCGGTTCTTCGCTTGTCCTAGCAAA GCCACCTTCTCGCGAAACATCATGAACCTGATCGACATTGTGGCCATCATTCCTTATTTT ATCACTCTGGGTACCGAGCTGGCCGAACGACAGGGCAATGGACAGCAGGCCATGTCTCTG GCCATCCTGAGGGTCATCCGCCTGGTAAGGGTCTTCCGCATCTTCAAGCTGTCGCGCCAC TCCAAGGGGCTGCAGATCCTCGGGCAAACGCTGAAGGCGTCCATGCGGGAGCTGGGATTG CTCATCTTCTTCCTCTTTATTGGGGTCATCCTTTTCTCCAGCGCGGTCTACTTTGCCGAG GCAGACGACCCCACTTCAGGTTTCAGCAGCATCCCGGATGCCTTCTGGTGGGCAGTGGTA ACCATGACAACAGTGGGTTACGGCGATATGCACCCAGTGACCATAGGGGGCAAGATTGTG GGATCTCTCTGTGCCATCGCCGGTGTCTTGACCATCGCATTGCCAGTTCCCGTGATTGTT TCCAACTTCAATTACTTCTACCACCGGGAGACAGAAGGGGAAGAGCAATCCCAGTACATG CACGTGGGAAGTTGCCAGCACCTCTCCTCTTCAGCCGAGGAGCTCCGAAAAGCAAGGAGT AACTCGACTCTGAGTAAGTCGGAGTATATGGTGATCGAAGAGGGGGGTATGAACCATAGC GCTTTCCCCCAGACCCCTTTCAAAACGGGCAATTCCACTGCCACCTGCACCACGAACAAT AATCCCAACTCTTGTGTCAACATCAAAAAGATATTCACCGATGTTTAA >OriGene 5' read for NM_002232 unedited
NGTCAAAATTTGTATACGACTCCTATAGGCGGCCGCGNAATTCGCACGAGNAGAGCATCG CGGCTTTGGCTGCAACAGGCGGTGGGCTCGGCTCGGGGGCGGAGGCGGCGAAAGGGCGGG GAGCGCGAGGAGGAGCGACCTGGCCTCACCGCTGCCGCCTCTTCCCCGCCGCATGGACGA GCGCCTCAGCCTTCTGCGCTCGCCGCCGCCGCCCTCAGCCCGCCACCGCGCCCACCCTCC TCAGCGCCCAGCGAGCAGCGGCGGTGCCCACACGCTGGTGAACCACGGCTACGCGGAGCC CGCCGCAGGCCGCGAGCTGCCGCCCGACATGACCGTGGTGCCCGGGGACCACCTGCTGGA GCCGGAGGTGGCCGATGGTGGAGGGGCCCCGCCTCAAGGCGGCTGTGGCGGCGGCGGCTG CGACCGCTACGAGCCGCTGCCGCCCTCACTGCCGGCCGCGGGCGAGCAGGACTGCTGCGG GGAGCGCGTGGTCATCAACATCTCCGGGCTGCGCTTCGAGACGCAGCTGAAGACCCTTTG CCAGTTCCCCGAGACGCTGCTGGGCGACCCCAAGCGGCGCATGAGGTACTTCGACCCGCT CCGCAACGAGTACTTCTTCGACCGCAACCGGCCCAGCTTCGACGCCATCCTCTACACTAT CAGTCNCGGGGGCCGCATCCGCCGGCCGGTCAACGTGCCCATCGACATTTTCTCGNAGGA GATCCGCTTCTACCAGCTGGGCGAGGAGGCCTTGGNANAAAGTCCGCGAGGACGAGGGCT TNNCTGCGGNAGGGAGGNAGCGGCCCTTGCCCCGNCGCGACTTCCACGCCCAGGGGTGGC TGCTCTTCGAGACCCGAGGACTCCCGGCCCGGCCCGGGCATGNCTANNGGGNCCCGGGCT GGGCATCTCATCTCCATTGCATCTCTGGCTGAACC >OriGene 3' read for NM_002232 unedited
AAAAAAGAGGTTGNCAGNCTGTCTTTATACTCTTCTTTGGGCACGTGTAGACTTCACTTA TTTATATGTAAATGGGCTAATCTATGTATGAGAGCCTTTGGTACAAAACACACCTTCACA AATAAAGTTGCACATAACCCAGAACATGGAATATAACACGACTATATCTCATGATTAAAC ACAGTCCACTACTTAATTGAAAAAAAAAAACAAANACAGTAATAGTTGGCTTGCTAGAAA ACAAATTTANGCTTTTCTTTCTGCAGCACTGATTATAGNTTTGGGATGATTCGATTTCAT CAAAATGTCAAAAGGTTGCAATGATACCTTAAAATTTTAACATTCTTAATTCTTTGAAGA AAAGGCTTTAATTTGCCCGCCTTTTGAAAGGAAATCCTCCAATTTAAGAGTGGTCCCTTT ATTAAAGGCTTTTGTTAGAGCATTTTTTTTAAGGGAACCGGGATAAAAAAATTTGGGGGG GGAAGGGGGACCCTGCCCCCCAAGAGGAATAACCGGGGCCCCGGTTTTTTTGCGCCCCGC GGTTTTAAAAGGGGGGCCTTCTTTTGGGGGGGGGGGCGGTTTTAACATTTTTTTTATGGG GGGGGGCTTTGTGGGGTCTTTTTTTTTCAAAAAGAGGGTCTTAATAATTTTTTAAAATTT TGGGGGGGGGGGGGTTTTTTTTTTTTTTTTTTTTTGGGGGGGGGGGGTTTCTCTTTTTTT TCCCCCGCGGGCGGGGGGGGGGGAGAGGGGGTCCCCCCCCCTTTTTTTTTTTTTTTTTTT TTTTTTCCCCCCCCTCTCTATTAGAGAAGAAAAACAAAAAGGGGGGTGTCCAAAACAAAA AAAGAAGGACCCCCCCCCCCCCCCTCCTTTATTAGGGGGGGGGGGGCCAAAACCTCAAAA AAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002232 |
| Insert Size | 4200 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to be a perfect match to NM_002232.3. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_002232.2, NP_002223.2 |
| RefSeq Size | 3303 bp |
| RefSeq ORF | 1572 bp |
| Locus ID | 3738 |
| UniProt ID | P22001 |
| Domains | BTB, K_tetra, ion_trans |
| Protein Families | Druggable Genome, Ion Channels: Potassium, Transmembrane |
| Gene Summary | Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. It plays an essential role in T-cell proliferation and activation. This gene appears to be intronless and it is clustered together with KCNA2 and KCNA10 genes on chromosome 1. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) encodes the functional protein. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Cell-free methods to produce structurally intact mammalian membrane proteins
,Shinoda, T;Shinya, N;Ito, K;Ishizuka-Katsura, Y;Ohsawa, N;Terada, T;Hirata, K;Kawano, Y;Yamamoto, M;Tomita, T;Ishibashi, Y;Hirabayashi, Y;Kimura-Someya, T;Shirouzu, M;Yokoyama, S;,
Sci Rep
,PubMed ID 27465719
[KCNA3]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207223 | KCNA3 (Myc-DDK-tagged)-Human potassium voltage-gated channel, shaker-related subfamily, member 3 (KCNA3) |
CNY 6,424.00 |
|
| RC207223L1 | Lenti ORF clone of Human potassium voltage-gated channel, shaker-related subfamily, member 3 (KCNA3), Myc-DDK-tagged |
CNY 8,824.00 |
|
| RC207223L2 | Lenti ORF clone of Human potassium voltage-gated channel, shaker-related subfamily, member 3 (KCNA3), mGFP tagged |
CNY 6,460.00 |
|
| RC207223L3 | Lenti ORF clone of Human potassium voltage-gated channel, shaker-related subfamily, member 3 (KCNA3), Myc-DDK-tagged |
CNY 8,824.00 |
|
| RC207223L4 | Lenti ORF clone of Human potassium voltage-gated channel, shaker-related subfamily, member 3 (KCNA3), mGFP tagged |
CNY 8,824.00 |
|
| RG207223 | KCNA3 (tGFP-tagged) - Human potassium voltage-gated channel, shaker-related subfamily, member 3 (KCNA3) |
CNY 8,024.00 |
|
| SC317985 | KCNA3 (untagged)-Human potassium voltage-gated channel, shaker-related subfamily, member 3 (KCNA3) |
CNY 6,432.00 |
