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GST3 (GSTP1) (NM_000852) Human Untagged Clone
CAT＃: SC119655
GSTP1 (untagged)-Human glutathione S-transferase pi 1 (GSTP1)
CNY 3,600.00
| Cited in 2 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DFN7; FAEES3; GST3; GSTP; HEL-S-22; PI |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC119655 sequence for NM_000852 edited (data generated by NextGen Sequencing)
ATGCCGCCCTACACCGTGGTCTATTTCCCAGTTCGAGGCCGCTGCGCGGCCCTGCGCATG CTGCTGGCAGATCAGGGCCAGAGCTGGAAGGAGGAGGTGGTGACCGTGGAGACGTGGCAG GAGGGCTCACTCAAAGCCTCCTGCCTATACGGGCAGCTCCCCAAGTTCCAGGACGGAGAC CTCACCCTGTACCAGTCCAATACCATCCTGCGTCACCTGGGCCGCACCCTTGGGCTCTAT GGGAAGGACCAGCAGGAGGCAGCCCTGGTGGACATGGTGAATGACGGCGTGGAGGACCTC CGCTGCAAATACATCTCCCTCATCTACACCAACTATGAGGCGGGCAAGGATGACTATGTG AAGGCACTGCCCGGGCAACTGAAGCCTTTTGAGACCCTGCTGTCCCAGAACCAGGGAGGC AAGACCTTCATTGTGGGAGACCAGATCTCCTTCGCTGACTACAACCTGCTGGACTTGCTG CTGATCCATGAGGTCCTAGCCCCTGGCTGCCTGGATGCGTTCCCCCTGCTCTCAGCATAT GTGGGGCGCCTCAGTGCCCGGCCCAAGCTCAAGGCCTTCCTGGCCTCCCCTGAGTACGTG AACCTCCCCATCAATGGCAACGGGAAACAGTGA Clone variation with respect to NM_000852.3 >OriGene 5' read for NM_000852 unedited
CACGAGGGCTCGGAGGCCGCGAGGCCTTCGCTGGAGTTTCGCCGCCGCAGTCTTCGCCAC CATGCCGCCCTACACCGTGGTCTATTTCCCAGTTCGAGGCCGCTGCGCGGCCCTGCGCAT GCTGCTGGCAGATCAGGGCCAGAGCTGGAAGGAGGAGGTGGTGACCGTGGAGACGTGGCA GGAGGGCTCACTCAAAGCCTCCTGCCTATACGGGCAGCTCCCCAAGTTCCAGGACGGAGA CCTCACCCTGTACCAGTCCAATACCATCCTGCGTCACCTGGGCCGCACCCTTGGGCTCTA TGGGAAGGACCAGCAGGAGGCAGCCCTGGTGGACATGGTGAATGACGGCGTGGAGGACCT CCGCTGCAAATACATCTCCCTCATCTACACCAACTATGAGGCGGGCAAGGATGACTATGT GAAGGCACTGCCCGGGCAACTGAAGCCTTTTGAGACCCTGCTGTCCCAGAACCAGGGAGG CAAGACCTTCATTGTGGGAGACCAGATCTCCTTCGCTGACTACAACCTGCTGGACTTGCT GCTGATCCATGAGGTCCTAGCCCCTGGCTGCCTGGATGCGTTCCCCCTGCTCTCAGCATA TGTGGGGCGCCTCAGTGCCCGGCCCAAGCTCAAGGCCTTCCTGGCCTCCCCTGAGTACGT GAACCTCCCCATCAATGGCAACGGGAAACAGTGAGGGTTGGGGGGACTCTGAG >OriGene 3' read for NM_000852 unedited
CGCGGGCCGCAATCTANAATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTTTTAACTCTCTTAAAAATTTATTGGTCCTGGAAAAAGGAAGGG AAACTTTGCCTCCCGCTTAAAATCCCCCCAACCCTTACTGTTTCCCGTTGCCATTGATGG GGAGGTTCACGTACTCAGGGGAGGCCAAAAAGGCCTTGAACTTGGGCCGGGCACTGAGGC CCCCCACATTTTCTGAAAACAGGGGGAACCCATCCAGGCACCCAGGGGCTAGGACCTCAT GGATCAACAGCAAGTCCAACAGGTTGTAATCAACGAAAGAAATCTGGTCTCCCACAATGA AAGGCTTGCCTCCCTGGTTCTGGGACAACAGGGTCTCAAAAGGGTTTAATTGCCCGGGCA GGGCCTTCACATAATCATCCTTGCCCCCCTCATAATTGGGGTAAATGAGGGAAAAGTATT TGCAGCGGAGGGCCTCCACCCCGTCATTCACCATGTCCACCAGGGCTGCCTCCTGCTGGT CCTTCCCATAAAACCCAAGGGTGCGGCCCAAGTGACCCAAGATGGTATTGGACTGGTACA GGGTGAGGGCTCCGTCCTGGACTTGGGGAGCTGCCCGTAAGGCAAGAAGCTTTGAATGAG CCCTTCTGGCACGTTTCCACGGGTAACCACCTCTCTTCCAATTTGGGCCTGGACTGCCAA CAAATGCCCAAGGGCCCCCAAGGCCTTAAACTGGGAATAAAACACGGGTAAGGCGGCATG TTGCAAAAACTTCGCGGGGAAACTCAAGAAAGGCCTCGGGCCCCAAACCTGTGCCAATTA GGGGCCCCCTTATGGAGCTATACAAAATTTGACGGTCACTAAAAACTTTGTTAAAGAACC TCCCGGCACCCCACCCCATTGGGCACGGG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000852 |
| Insert Size | 870 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000852.2, NP_000843.1 |
| RefSeq Size | 737 bp |
| RefSeq ORF | 633 bp |
| Locus ID | 2950 |
| UniProt ID | P09211 |
| Domains | GST_N, GST_C |
| Protein Families | Druggable Genome |
| Protein Pathways | Drug metabolism - cytochrome P450, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, Prostate cancer |
| Gene Summary | Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases. [provided by RefSeq, Jul 2008] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Glutathione S-Transferase P1 Protects Against Amodiaquine Quinoneimines-Induced Cytotoxicity but Does Not Prevent Activation of Endoplasmic Reticulum Stress in HepG2 Cells
,Zhang, Y;den Braver-Sewradj, SP;den Braver, MW;Hiemstra, S;Vermeulen, NPE;van de Water, B;Commandeur, JNM;Vos, JC;,
Front Pharmacol
,PubMed ID 29720942
[GSTP1]
|
|
Sirtuin 3 enhanced drug sensitivity of human hepatoma cells through glutathione S-transferase pi 1/JNK signaling pathway
,Tao, NN;Zhou, HZ;Tang, H;Cai, XF;Zhang, WL;Ren, JH;Zhou, L;Chen, X;Chen, K;Li, WY;Liu, B;Yang, QX;Cheng, ST;Huang, LX;Huang, AL;Chen, J;,
Oncotarget
,PubMed ID 27367026
[GSTP1]
|
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Resources
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