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CXCR1 (NM_000634) Human Untagged Clone
CAT＃: SC119771
CXCR1 (untagged)-Human chemokine (C-X-C motif) receptor 1 (CXCR1)
CNY 2,950.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | C-C; C-C-CKR-1; CD128; CD181; CDw128a; CKR-1; CMKAR1; IL8R1; IL8RA; IL8RBA |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_000634 edited
GAATTCGGCACGAGGCAGCTCCTACTGTTGGACACACCTGGCCGGTGCTTCAGTTAGATC AAACCATTGCTGAAACTGAAGAGGACATGTCAAATATTACAGATCCACAGATGTGGGATT TTGATGATCTAAATTTCACTGGCATGCCACCTGCAGATGAAGATTACAGCCCCTGTATGC TAGAAACTGAGACACTCAACAAGTATGTTGTGATCATCGCCTATGCCCTAGTGTTCCTGC TGAGCCTGCTGGGAAACTCCCTGGTGATGCTGGTCATCTTATACAGCAGGGTCGGCCGCT CCGTCACTGATGTCTACCTGCTGAACCTGGCCTTGGCCGACCTACTCTTTGCCCTGACCT TGCCCATCTGGGCCGCCTCCAAGGTGAATGGCTGGATTTTTGGCACATTCCTGTGCAAGG TGGTCTCACTCCTGAAGGAAGTCAACTTCTACAGTGGCATCCTGCTGTTGGCCTGCATCA GTGTGGACCGTTACCTGGCCATTGTCCATGCCACACGCACACTGACCCAGAAGCGTCACT TGGTCAAGTTTGTTTGTCTTGGCTGCTGGGGACTGTCTATGAATCTGTCCCTGCCCTTCT TCCTTTTCCGCCAGGCTTACCATCCAAACAATTCCAGTCCAGTTTGCTATGAGGTCCTGG GAAATGACACAGCAAAATGGCGGATGGTGTTGCGGATCCTGCCTCACACCTTTGGCTTCA TCGTGCCGCTGTTTGTCATGCTGTTCTGCTATGGATTCACCCTGCGTACACTGTTTAAGG CCCACATGGGGCAGAAGCACCGAGCCATGAGGGTCATCTTTGCTGTCGTCCTCATCTTCC TGCTTTGCTGGCTGCCCTACAACCTGGTCCTGCTGGCAGACACCCTCATGAGGACCCAGG TGATCCAGGAGAGCTGTGAGCGCCGCAACAACATCGGCCGGGCCCTGGATGCCACTGAGA TTCTGGGATTTCTCCATAGCTGCCTCAACCCCATCATCTACGCCTTCATCGGCCAAAATT TTCGCCATGGATTCCTCAAGATCCTGGCTATGCATGGCCTGGTCAGCAAGGAGTTCTTGG CACGTCATCGTGTTACCTCCTACACTTCTTCGTCTGTCAATGTCTCTTCCAACCTCTGAA AACCATCGATGAAGGAATATCTCTTCTCAGAAGGAAAGAATAACCAACACCCTGAGGTTG TGTGTGGAAGGTGATCTGGCTCTGGACAGGCACTATCTGGGTTTTGGGGGGACGCTATAG GATGTGGGGAAGTTAGGAACTGGTGTCTTCAGGGGCCACACCAACCTTCTGAGGAGCTGT TGAGGTACCTCCAAGGACCGGCCTTTGCACCTCCATGGAAACGAAGCACCATCATTCCCG TTGAACGTCACATCTTTAACCCACTAACTGGCTAATTAGCATGGCCACATCTGAGCCCCG AATCTGACATTAGATGAGAGAACAGGGCTGAAGCTGTGTCCTCATGAGGGCTGGATGCTC TCGTTGACCCTCACAGGAGCATCTCCTCAACTCTGAGTGTTAAGCGTTGAGCCACCAAGC TGGTGGCTCTGTGTGCTCTGATCCGAGCTCAGGGGGGTGGTTTTCCCATCTCAGGTGTGT TGCAGTGTCTGCTGGAGACATTGAGGCAGGCACTGCCAAAACATCAACCTGCCAGCTGGC CTTGTGAGGAGCTGGAAACACATGTTCCCCTTGGGGGTGGTGGATGAACAAAGAGAAAGA GGGTTTGGAAGCCAGATCTATGCCACAAGAACCCCCTTTACCCCCATGACCAACATCGCA GACACATGTGCTGGCCACCTGCTGAGCCCCAAGTGGAACGAGACAAGCAGCCCTTAGCCC TTCCCCTCTGCAGCTTCCAGGCTGGCGTGCAGCATCAGCATCCCTAGAAAGCCATGTGCA GCCACCAGTCCATTGGGCAGGCAGATGTTCCTAATAAAGCTTCTGTTCCGTGCTTGTCCC TGTGGAAGTATCTTGGTTGTGACAGAGTCAAGGGTGTGTGCAGCATTGTTGGCTGTTCCT GCAGTAGAATGGGGGCAGCACCTCCTAAGAAGGCACCTCTCTGGGTTGAAGGGCAGTGTT CCCTGGGGCTTTAACTCCTGCTAGAACAGTCTCTTGAGGCACAGAAACTCCTGTTCATGC CCATACCCCTGGCCAAGGAAGATCCCTTTGTCCACAAGTAAAAGGAAATGCTCCTCCAGG GAGTCTCAGCTTCACCCTGAGGTGAGCATCATCTTCTGGGTTAGGCCTTGCCTAGGCATA GCCCTGCCTCAAGCTATGTGAGCTCACCAGTCCCTCCCCAAATGCTTTCCATGAGTTGCA GTTTTTTCCTAGTCTGTTTTCCCTCCTTGGAGACAGGGCCCTGTCGGTTTATTCACTGTA TGTCCTTGGTGCCTGGAGCCTACTAAATGCTCAATAAATAATGATCACAGGAAAAAAAAA AAAAAAAAAACTCGAC >OriGene 5' read for NM_000634 unedited
NAAAANNAAANNAAANNAAAAAAANNNAAAANTTGTTCAGAATTTGTCATACGACTTATA TAGGGCGGCCGCGAATTCGCACGAGGCAGCTCCTACTGTTGGACACACCTGGCCGGTGCT TCAGTTAGATCAAACCATTGCTGAAACTGAAGAGGACATGTCAAATATTACAGATCCACA GATGTGGGATTTTGATGATCTAAATTTCACTGGCATGCCACCTGCAGATGAAGATTACAG CCCCTGTATGCTAGAAACTGAGACACTCAACAAGTATGTTGTGATCATCGCCTATGCCCT AGTGTTCCTGCTGAGCCTGCTGGGAAACTCCCTGGTGATGCTGGTCATCTTATACAGCAG GGTCGGCCGCTCCGTCACTGATGTCTACCTGCTGAACCTGGCCTTGGCCGACCTACTCTT TGCCCTGACCTTGCCCATCTGGGCCGCCTCCAAGGTGAATGGCTGGATTTTTGGCACATT CCTGTGCAAGGTGGTCTCACTCCTGAAGGAAGTCAACTTCTACAGTGGCATCCTGCTGTT GGCCTGCATCAGTGTGGACCGTTACCTGGCCATTGTCCATGCCACACGCACACTGACCCA GAAGCGTCACTTGGTCAAGNTTGTTTGTCTTGGCTGCTGGGGACTGTCTATGAATCTGTC CCTGCCCTTTTTTCTTTTCCGGCAGGCTTACCATTCCAACAATTCCAGTCCAGTTTGCTA TGAGGTCCTGGGAAATGACACAGCACAATGGCGGATGGTGTTGCGGATCCTGCCTCACAC CTTTGGCTTTATTGCGCCCGTTGTTTGGCATGCTGTTCTGCTATGGGATCACCCTTGGTA CACTGTTTAAAGCCCCAAGGNGGCCAAACACCGAGCCCTGAGGGGCATTTTTGGTGTCGG CCTCACCTTCTGCTTGCTGGGGGCCTACAACCTGGCCTGTGGGCGACCCCCTATGAGGAC CCGGG >OriGene 3' read for NM_000634 unedited
GGGGGGCCANNNNNGNNNCCTCCCNNNNNANNNNGGTCTTAGNACCGCGCCGCATTTTAN GATCGAGTTTTTTTTTTTTTTTTTTTCCTGTGNACATTATTTATTGAGCATTTAGTAGGC TCCAGGCACCAAGGAACATACAGTGAATAAACCGACAGGGCCCTGTCTCCAAGGAGGGAA AACAGACTAGGAAAAAACTGCAACTCATGGAAAGCATTTGGGGAGGGACTGGTGAGCTCA CATAGCTTGAGGCAGGGCTATGCCTAGGCAAGGCCTAACCCAGAAGATGATGCTCACCTC AGGGTGAAGCTGAGACTCCCTGGAGGAGCATTTCCTTTTACTTGTGGACAAAGGGATCTT CCTTGGCCAGGGGTATGGGCATGAACAGGAGTTTCTGTGCCTCAAGAGACTGTTCTAGCA GGAGTTAAAGCCCCAGGGAACACTGCCCTTCAACCCAGAGAGGTGCCTTCTTAGGAGGTG CTGCCCCCATTCTACTGCAGGAACAGCCAACAATGCTGCACACACCCTTGACTCTGTCAC AACCAAGATACTTCCACAGGGACAAGCACGGAACAGAAGCTTTATTAGGAACATCTGCCT GCCCAATGGACTGGTGGCTGCACATGGCTTTCTAGGGATGCTGATGCTGCACGCANCCTG GAAGCTGCAGAGGGGAAGGGCTAAGGNCTGCTTGTCTCGTTCCACTTGGGGCTCAGCANG TGCCAGCACATGTGTCTGCGATGNTGGTCATGGGGGNTAAGGGGGGTTCTGTGGCATAAA ATCTGGCTTCAAAACCTCTTTCTCTTTGTTCATCCACCACCCCCAGGGGAACATGTGGTT CCAGCTCCTCACAAGCCAACTGGCANGTTGATGTTTTGGCAATGCCCTGCTAAATGCTCC AACGAACCTGAACCAACCTGAAATGGGAAACCCCCCCCTGACCTGGATCAAACCCACAAA GCCACCAGCTTGGGGCTTACCCTTAACCTCAAAGTTGAGGGAAGCCCC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000634 |
| Insert Size | 2500 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000634.2, NP_000625.1 |
| RefSeq Size | 2502 bp |
| RefSeq ORF | 1053 bp |
| Locus ID | 3577 |
| UniProt ID | P25024 |
| Domains | 7tm_1 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection |
| Gene Summary | The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq, Jul 2008] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Cell-free methods to produce structurally intact mammalian membrane proteins
,Shinoda, T;Shinya, N;Ito, K;Ishizuka-Katsura, Y;Ohsawa, N;Terada, T;Hirata, K;Kawano, Y;Yamamoto, M;Tomita, T;Ishibashi, Y;Hirabayashi, Y;Kimura-Someya, T;Shirouzu, M;Yokoyama, S;,
Sci Rep
,PubMed ID 27465719
[CXCR1]
|
|
AUF1 and HuR Proteins Stabilize Interleukin-8 mRNA in Human Saliva
,V. Palanisamy, N.J. Park, J. Wang, and D.T. Wong,
J. Dent. Res., Aug 2008; 87: 772 - 776.
[CXCR1]
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Resources
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