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beta Sarcoglycan (SGCB) (NM_000232) Human Untagged Clone
CAT＃: SC120022
SGCB (untagged)-Human sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) (SGCB)
CNY 2,400.00
CNY 2,950.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | A3b; LGMD2E; LGMDR4; SGC |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_000232, the custom clone sequence may differ by one or more nucleotides
ATGGCGGCAGCGGCGGCGGCGGCTGCAGAACAGCAAAGTTCCAATGGTCCTGTAAAGAAGTCCATGCGTG AGAAGGCTGTTGAGAGAAGGAGTGTCAATAAAGAGCACAACAGTAACTTTAAAGCTGGATACATTCCGAT TGATGAAGATCGTCTCCACAAAACAGGGTTGAGAGGAAGAAAGGGCAATTTAGCCATCTGTGTGATTATC CTCTTGTTTATCCTGGCTGTCATCAATTTAATAATAACACTTGTTATTTGGGCCGTGATTCGCATTGGAC CAAATGGCTGTGATAGTATGGAGTTTCATGAAAGTGGCCTGCTTCGATTTAAGCAAGTATCTGACATGGG AGTGATCCACCCTCTTTATAAAAGCACAGTAGGAGGAAGGCGAAATGAAAATTTGGTCATCACTGGCAAC AACCAGCCTATTGTTTTTCAGCAAGGGACAACAAAGCTCAGTGTAGAAAACAACAAAACTTCTATTACAA GTGACATCGGCATGCAGTTTTTTGACCCGAGGACTCAAAATATCTTATTCAGCACAGACTATGAAACTCA TGAGTTTCATTTGCCAAGTGGAGTGAAAAGTTTGAATGTTCAAAAGGCATCTACTGAAAGGATTACCAGC AATGCTACCAGTGATTTAAATATAAAAGTTGATGGGCGTGCTATTGTGCGTGGAAATGAAGGTGTATTCA TTATGGGCAAAACCATTGAATTTCACATGGGTGGTAATATGGAGTTAAAGGCGGAAAACAGTATCATCCT AAATGGATCTGTGATGGTCAGCACCACCCGCCTACCCAGTTCCTCCAGTGGAGACCAGTTGGGTAGTGGT GACTGGGTACGCTACAAGCTCTGCATGTGTGCTGATGGGACGCTCTTCAAGGTGCAAGTAACCAGCCAGA ACATGGGCTGCCAAATCTCAGACAACCCCTGTGGAAACACTCATTAA >OriGene 5' read for NM_000232 unedited
TTTGTAATACGACTCACTATAGGGGCGGCCGCGAATTCGCACGAGGGGAAGATGGCGGCA GCGGCGGCGGCGGCTGCAGAACAGCAAAGTTCCAATGGTCCTGTAAAGAAGTCCATGCGT GAGAAGGCTGTTGAGAGAAGGAGTGTCAATAAAGAGCACAACAGTAACTTTAAAGCTGGA TACATTCCGATTGATGAAGATCGTCTCCACAAAACAGGGTTGAGAGGAAGAAAGGGCAAT TTAGCCATCTGTGTGATTATCCTCTTGTTTATCCTGGCTGTCATCAATTTAATAATAACA CTTGTTATTTGGGCCGTGATTCGCATTGGACCAAATGGCTGTGATAGTATGGAGTTTCAT GAAAGTGGCCTGCTTCGATTTAAGCAAGTATCTGACATGGGAGTGATCCACCCTCTTTAT AAAAGCACAGTAGGAGGAAGGCGAAATGAAAATTTGGTCATCACTGGCAACAACCAGCCT ATTGTTTTTCAGCAAGGGACAACAAAGCTCAGTGTAGAAAACAACAAAACTTCTATTACA AGTGACATCGGCATGCAGTTTTTTGACCCGAGGACTCAAAATATCTTATTCAGCACAGAC TATGAAACTCATGAGTTTCATTTGCCAAGTGGAGTGAAAAGTTTGAATGTTCAAAAGGCA TCTACTGAAAGGGATTACCAGCATGCTACCAGTGATTTAATATAAAAGTGATNGGGCGTG CTATNGGTGCGTGGAAATGAANGGTGTATTCATTATGGGCAAAACCATTGAATTTACATG GNGTGGTATNNATGGAGTTAAAGGCGGNAAACAGTATCATCTAAATGGATCTGTGATGGT CAGCACCACCCGCTACCCANTNNNCTCATGAGACANNTGGGGNANTGGGGACTTGGGACC TACAGCTCTGGATGGTGCTGATGGGACCT >OriGene 3' read for NM_000232 unedited
CCGCGGCACGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTCAATTTACAGAATTTTT ATTGTAAACAGAAGCTCATTACTAGTTATTACAAACTGAATCAACTGAAACTCAAGTTAG CAATGTGAAACACATTTATAGGCTTATTTTTGTATACCATAATTGGTAATTTTTGCCCCC TCAATACTTTTAAAAAGACTGTTAAAATTTTCAGCATTTCAATGATCTCTTATTTGTCAG GTTTAGCACCATGACATTCTCATTCCCTTAAAAAAACACTCATTCAAATCTAGGTAGAAC TTCCACCTTTCATCATCAAAATTATCACACAAAATTTATTTTGTTTTTTTCACAATGCAA AAAGAAGACAAATAAGTATATTTTAAAATATTATCAGCAGTCCGTTTTGTGTGGTTTTAC ATTTTTCTGTCTGCCCATTATTAAAAAATCTTGCATTGATTTCATTTGCCCCCCTTGTCA TTGCAACCCGTCTCTAGAATACTGTGGTAATTGAAACTAGCATGTACCTGCGCCCCCTCC CGGGGTCCTATCTTTGTCACCCACCTCCCCCATGGCTACTGCTTGTCATATCTGTGCTCA GTGCAGGGATGAGCATACAGCAGGAAGAGGCGAAGTCAGCATTTCATTTACAGAAAAATA CTATCTGGTGGAGACAATGAGTTGCTGAAGATTTACTGTGGATAAAAATAAGCCGGCCAG GCGTGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAGGCAGATCACGA TGTCAAGAGATTGAGACCATCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATAC AAAAATTANCCCGGGACTGTGGCACATGCCTGTAGTCCCAGTACTCGGGAAGGCTGAGCA GAGAATCGCTTGACCCCTGGAGCANAGNTGCATGATCCANAGCGATTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000232 |
| Insert Size | 4000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000232.3, NP_000223.1 |
| RefSeq Size | 4229 bp |
| RefSeq ORF | 957 bp |
| Locus ID | 6443 |
| UniProt ID | Q16585 |
| Domains | sarcoglycan |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), Viral myocarditis |
| Gene Summary | This gene encodes a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with limb-girdle muscular dystrophy.[provided by RefSeq, Oct 2008] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Evidence of associations of APOBEC3B gene deletion with susceptibility to persistent HBV infection and hepatocellular carcinoma
,Tongwen Zhang, Jianqiang Cai, Jiang Chang, Dianke Yu, Chen Wu, Tao Yan, Kan Zhai, Xinyu Bi, Hong Zhao, Jian Xu, Wen Tan, Chunfeng Qu, and Dongxin Lin,
Hum. Mol. Genet., Mar 2013; 22: 1262 - 1269.
[SGCB]
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SGCE missense mutations that cause myoclonus-dystonia syndrome impair {varepsilon}-sarcoglycan trafficking to the plasma membrane: modulation by ubiquitination and torsinA,
,Christopher T. Esapa, Adrian Waite, Matthew Locke, Matthew A. Benson, Michaela Kraus, R.A. Jeffrey McIlhinney, Roy V. Sillitoe, Philip W. Beesley, Derek J. Blake,
Hum Mol Genet. 2007 Feb 1;16(3):327-42.
[SGCB]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204699 | SGCB (Myc-DDK-tagged)-Human sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) (SGCB) |
CNY 2,400.00 |
|
| RC204699L3 | Lenti ORF clone of Human sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) (SGCB), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC204699L4 | Lenti ORF clone of Human sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) (SGCB), mGFP tagged |
CNY 5,890.00 |
|
| RG204699 | SGCB (tGFP-tagged) - Human sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) (SGCB) |
CNY 4,000.00 |
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