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GABA A Receptor gamma 2 (GABRG2) (NM_198903) Human Untagged Clone
CAT＃: SC121595
GABRG2 (untagged)-Human gamma-aminobutyric acid (GABA) A receptor, gamma 2 (GABRG2), transcript variant 3
CNY 3,600.00
| Cited in 3 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CAE2; DEE74; ECA2; EIEE74; FEB8; GEFSP3 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_198903, the custom clone sequence may differ by one or more nucleotides
ATGAGTTCGCCAAATATATGGAGCACAGGAAGCTCAGTCTACTCGACTCCTGTATTTTCACAGAAAATGA CGGTGTGGATTCTGCTCCTGCTGTCGCTCTACCCTGGCTTCACTAGCCAGAAATCTGATGATGACTATGA AGATTATGCTTCTAACAAAACATGGGTCTTGACTCCAAAAGTTCCTGAGGGTGATGTCACTGTCATCTTA AACAACCTGCTGGAAGGATATGACAATAAACTTCGGCCTGATATAGGAGTGAAGCCAACGTTAATTCACA CAGACATGTATGTGAATAGCATTGGTCCAGTGAACGCTATCAATATGGAATACACTATTGATATATTTTT TGCGCAAACGTGGTATGACAGACGTTTGAAATTTAACAGCACCATTAAAGTCCTCCGATTGAACAGCAAC ATGGTGGGGAAAATCTGGATTCCAGACACTTTCTTCAGAAATTCCAAAAAAGCTGATGCACACTGGATCA CCACCCCCAACAGGATGCTGAGAATTTGGAATGATGGTCGAGTGCTCTACACCCTAAGGTTGACAATTGA TGCTGAGTGCCAATTACAATTGCACAACTTTCCAATGGATGAACACTCCTGCCCCTTGGAGTTCTCCAGT TGGTCTCGTTCTATTGCCCAGGCTGGAATGTGCAGTGGTGTGATCTCGGCTCACTACAGCCTTCGCTTCT GGGGCTCAACTGATCCTCCCACCTTGGCCTCCAGAGTAGCTGGGATTTCAGATGGCTATCCACGTGAAGA AATTGTTTATCAATGGAAGCGAAGTTCTGTTGAAGTGGGCGACACAAGATCCTGGAGGCTTTATCAATTC TCATTTGTTGGTCTAAGAAATACCACCGAAGTAGTGAAGACAACTTCCGGAGATTATGTGGTCATGTCTG TCTACTTTGATCTGAGCAGAAGAATGGGATACTTTACCATCCAGACCTATATCCCCTGCACACTCATTGT CGTCCTATCCTGGGTGTCTTTCTGGATCAATAAGGATGCTGTTCCAGCCAGAACATCTTTAGGTATCACC ACTGTCCTGACAATGACCACCCTCAGCACCATTGCCCGGAAATCGCTCCCCAAGGTCTCCTATGTCACAG CGATGGATCTCTTTGTATCTGTTTGTTTCATCTTTGTCTTCTCTGCTCTGGTGGAGTATGGCACCTTGCA TTATTTTGTCAGCAACCGGAAACCAAGCAAGGACAAAGATAAAAAGAAGAAAAACCCTCTTCTTCGGATG TTTTCCTTCAAGGCCCCTACCATTGATATCCGCCCAAGATCAGCAACCATTCAAATGAATAATGCTACAC ACCTTCAAGAGAGAGATGAAGAGTACGGCTATGAGTGTCTGGACGGCAAGGACTGTGCCAGTTTTTTCTG CTGTTTTGAAGATTGTCGAACAGGAGCTTGGAGACATGGGAGGATACATATCCGCATTGCCAAAATGGAC TCCTATGCTCGGATCTTCTTCCCCACTGCCTTCTGCCTGTTTAATCTGGTCTATTGGGTCTCCTACCTCT ACCTGTGA >OriGene 5' read for NM_198903 unedited
GCTTTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCCTCGTGCCGAATT CGGCACGAGTTAAGTCCTCCGATGAACAGCACATGGTGGGGAAAATCTGGATTCCAGACA CTTTCTTCAGAAATTCCAAAAAAGCTGATGCACACTGGATCACCACCCCCAACAGGATGC TGAGAATTTGGAATGATGGTCGAGTGCTCTACACCCTAAGGTTGACAATTGATGCTGAGT GCCAATTACAATTGCACAATTTTCCAATGGATGAACACTCCTGCCCCTTGGAGTTCTCCA GTTATGGCTATCCACGTGAAGAAATTGTTTATCAATGGAAGCGAAGTTCTGTTGAAGTGG GCGACACAAGATCCTGGAGGCTTTATCAATTCTCATTTGTTGGTCTAAGAAATACCACCG AAGTAGTGAAGACAACTTCCGGAGATTATGTGGTCATGTCTGTCTACTTTGATCTGAGCA GAAGAATGGGATACTTTACCATCCAGACCTATATCCCCTGCACACTCATTGTCGTCCTAT CCTGGGTGTCTTTCTGGATCAATAAGGATGCTGTTCCAGCCAGAACATCTTTAGGTATCA CCACTGTCCTGACAATGACCACCCTCAGCACCATTGCCCCGGAATCGCTCCCCAAGGTCT NCTATGTCACAGCGATGGATCTCTNTGNATCTGGTTGGTTCATCTTTGTCTTCTCTGCTC TGGGGNAGTATGGCACCTTGCATTATTNTGTCAGCACCGNGAAACCAGCAGGGACAAGAT AAAAGAAGAAAAACCTTTCTTTCGATGTTTTCCTTCAGGGCCCTACATTGATATCGCCCC AGATCAGCACCATCAATGATATGCTACCACCTCAAAAAAATGAAAGACGCTATGANGNCT GC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_198903 |
| Insert Size | 1600 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_198903.1, NP_944493.1 |
| RefSeq Size | 4077 bp |
| RefSeq ORF | 984 bp |
| Locus ID | 2566 |
| UniProt ID | P18507 |
| Protein Families | Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane |
| Protein Pathways | Neuroactive ligand-receptor interaction |
| Gene Summary | This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (3) encodes the longest isoform (3). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Clinical characteristics and outcome of patients with autoimmune encephalitis: clues for paraneoplastic etiology
,Iorio, R;Damato, V;Spagni, G;Della Marca, G;Vollono, C;Masi, G;Papi, C;Campetella, L;Monte, G;Evoli, A;,
Eur. J. Neurol.
,PubMed ID 32412135
[GABRG2]
|
|
Clinical and immunological characteristics of the spectrum of GFAP autoimmunity: a case series of 22 patients.
,null,
Journal of neurology, neurosurgery, and psychiatry
,PubMed ID 28951498
[GABRG2]
|
|
Febrile infection-related epilepsy syndrome (FIRES) with super-refractory status epilepticus revealing autoimmune encephalitis due to GABAAR antibodies
,Caputo, D;Iorio, R;Vigevano, F;Fusco, L;,
Eur. J. Paediatr. Neurol.2017
,PubMed ID 29203057
[GABRG2]
|
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210173 | GABRG2 (Myc-DDK-tagged)-Human gamma-aminobutyric acid (GABA) A receptor, gamma 2 (GABRG2), transcript variant 3 |
CNY 5,488.00 |
|
| RC210173L3 | Lenti ORF clone of Human gamma-aminobutyric acid (GABA) A receptor, gamma 2 (GABRG2), transcript variant 3, Myc-DDK-tagged |
CNY 6,370.00 |
|
| RC210173L4 | Lenti ORF clone of Human gamma-aminobutyric acid (GABA) A receptor, gamma 2 (GABRG2), transcript variant 3, mGFP tagged |
CNY 6,370.00 |
|
| RG210173 | GABRG2 (tGFP-tagged) - Human gamma-aminobutyric acid (GABA) A receptor, gamma 2 (GABRG2), transcript variant 3 |
CNY 7,088.00 |
|
| SC327898 | GABRG2 (untagged)-Human gamma-aminobutyric acid (GABA) A receptor gamma 2 (GABRG2) transcript variant 3 |
CNY 6,144.00 |
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