Frizzled 7 (FZD7) (BC015915) Human Untagged Clone

Name: Frizzled 7 (FZD7) (BC015915) Human Untagged Clone
SKU: SC122259
Price: 4272.00

CAT＃: SC122259

FZD7 (untagged)-Human frizzled homolog 7 (Drosophila) (cDNA clone MGC:20119 IMAGE:4549389), complete cds

Datasheet

SDS

CNY 2,950.00

货期*

现货

规格

Cited in 4 publications.

Product images

经常一起买 (4)

TA344065

Rabbit Polyclonal Anti-FZD7 Antibody

CNY 5,200.00

TF81001

TurboFectin Transfection Reagent (1 mL in 1 vial)

CNY 4,090.00

CC100003

DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)

CNY 1,280.00

PRIMER

Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each

CNY 480.00

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	Frizzled, drosophila, homolog of, 7; frizzled 7; frizzled homolog 7 (Drosophila); FzE3
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for NM_003507 edited ACTCGCGGCCGGCGATGCGGGACCCCGGCGCGGCCGCTCCGCTTTCGTCCCTGGGCCTCT GTGCCCTGGTGCTGGCGCTGCTGGGCGCACTGTCCGCGGGCGCCGGGGCGCAGCCGTACC ACGGAGAGAAGGGCATCTCCGTGCCGGACCACGGCTTCTGCCAGCCCATCTCCATCCCGC TGTGCACGGACATCGCCTACAACCAGACCATCCTGCCCAACCTGCTGGGCCACACGAACC AAGAGGACGCGGGCCTCGAGGTGCACCAGTTCTACCCGCTGGTGAAGGTGCAGTGTTCTC CCGAACTCCGCTTTTTCTTATGCTCCATGTATGCGCCCGTGTGCACCGTGCTCGATCAGG CCATCCCGCCGTGTCGTTCTCTGTGCGAGCGCGCCCGCCAGGGCTGCGAGGCGCTCATGA ACAAGTTCGGCTTCCAGTGGCCCGAGCGGCTGCGCTGCGAGAACTTCCCGGTGCACGGTG CGGGCGAGATCTGCGTGGGCCAGAACACGTCGGACGGCTCCGGGGGCCCAGGCGGCGGCC CCACTGCCTACCCTACCGCGCCCTACCTGCCGGACCTGCCCTTCACCGCGCTGCCCCCGG GGGCCTCAGATGGCAGGGGGCGTCCCGCCTTCCCCTTCTCATGCCCCCGTCAGCTCAAGG TGCCCCCGTACCTGGGCTACCGCTTCCTGGGTGAGCGCGATTGTGGCGCCCCGTGCGAAC CGGGCCGTGCCAACGGCCTGATGTACTTTAAGGAGGAGGAGAGGCGCTTCGCCCGCCTCT GGGTGGGCGTGTGGTCCGTGCTGTGCTGCGCCTCGACGCTCTTTACCGTTCTCACCTACC TGGTGGACATGCGGCGCTTCAGCTACCCAGAGCGGCCCATCATCTTCCTGTCGGGCTGCT ACTTCATGGTGGCCGTGGCGCACGTGGCCGGCTTCCTTCTAGAGGACCGCGCCGTGTGCG TGGAGCGCTTCTCGGACGATGGCTACCGCACGGTGGCGCAGGGCACCAAGAAGGAGGGCT GCACCATCCTCTTCATGGTGCTCTACTTCTTCGGCATGGCCAGCTCCATCTGGTGGGTCA TTCTGTCTCTCACTTGGTTCCTGGCGGCCGGCATGAAGTGGGGCCACGAGGCCATCGAGG CCAACTCGCAGTACTTCCACCTGGCCGCGTGGGCCGTGCCCGCCGTCAAGACCATCACTA TCCTGGCCATGGGCCAGGTAGACGGGGACCTGCTGAGCGGGGTGTGCTACGTTGGCCTCT CCAGTGTGGACGCGCTGCGGGGCTTCGTGCTGGCGCCTCTGTTCGTCTACCTCTTCATAG GCACGTCCTTCTTGCTGGCCGGCTTCGTGTCCCTCTTCCGTATCCGCACCATCATGAAAC ACGACGGCACCAAGACCGAGAAGCTGGAGAAGCTCATGGTGCGCATCGGCGTCTTCAGCG TGCTCTACACAGTGCCCGCCACCATCGTCCTGGCCTGCTACTTCTACGAGCAGGCCTTCC GCGAGCACTGGGAGCGCACCTGGCTCCTGCAGACGTGCAAGAGCTATGCCGTGCCCTGCC CGCCCGGCCACTTCCCGCCCATGAGCCCCGACTTCACCGTCTTCATGATCAAGTACCTGA TGACCATGATCGTCGGCATCACCACTGGCTTCTGGATCTGGTCGGGCAAGACCCTGCAGT CGTGGCGCCGCTTCTACCACAGACTTAGCCACAGCAGCAAGGGGGAGACTGCGGTATGAG CCCCGGCCCCTCCCCACCTTTCCCACCCCAGCCCTCTTGCAAGAGGAGAGGCACGGTAGG GAAAAGAACTGCTGGGTGGGGGCCTGTTTCTGTAACTTTCTCCCCCTCTACTGAGAAGTG ACCTGGAAGTGAGAAGTTTTTTGCAGATTTGGGGCGAGGGGTGATTTGGAAAAGAAGACC TGTGTGGAAAGCGGTTTGGATGAAAAGATTTCAGGCAAAGACTTGCAGGAAGATGATGAT AACGGCGATGTGAATCGTCAAAGGTACGGGCCAGCTTGTGCCTAATAGAAGGTTGAGACC AGCAGAGACTGCTGTGAGTTTCTCCCGGCTCCGAGGCTGAACGGGGACTGTGAGCGATCC CCCTGCTGCAGGGCGAGTGGCCTGTCCAGACCCCTGTGAGGCCCCGGGAAAGGTACAGCC CTGTCTGCGGTGGCTGCTTTGTTGGAAAGAGGGAGGGCCTCCTGCGGTGTGCTTGTCAAG CAGTGGTCAAACCATAATCTCTTTTCACTGGGGCCAAACTGGAGCCCAGATGGGTTAATT TCCAGGGTCAGACATTACGGTCTCTCCTCCCCTGCCCCCTCCCGCCTGTTTTTCCTCCCG TACTGCTTTCAGGTCTTGTAAAATAAGCATTTGGAAGTCTTGGGAGGCCTGCCTGCTAGA ATCCTAATGTGAGGATGCAAAAGAAATGATGATAACATTTTGAGATAAGGCCAAGGAGAC GTGGAGTAGGTATTTTTGCTACTTTTTCATTTTCTGGGGAAGGCAGGAGGCAGAAAGACG GGTGTTTTATTTGGTCTAATACCCTGAAAAGAAGTGATGACTTGTTGCTTTTCAAAACAG GAATGCATTTTTCCCCTTGTCTTTGTTGTAAGAGACAAAAGAGGAAACAAAAGTGTCTCC CTGTGGAAAGGCATAACTGTGACGAAAGCAACTTTTATAGGCAAAGCAGCGCAAATCTGA GGTTTCCCGTTGGTTGTTAATTTGGTTGAGATAAACATTCCTTTTTAAGGAAAAGTGAAG AGCAGTGTGCTGTCACACACCGTTAAGCCAGAGGTTCTGACTTCGCTAAAGGAAATGTAA GAGGTTTTGTTGTCTGTTTTAAATAAATTTAATTCGGAACACATGATCCAACAGACTATG TTAAAATATTCAGGGAAATCTCTCCCTTCATTTACTTTTTCTTGCTATAAGCCTATATTT AGGTTTCTTTTCTATTTTTTTCTCCCATTTGGATCCTTTGAGGTAAAAAAACATAATGTC TTCAGCCTCATAATAAAGGAAAGTTAATTAAAAAAAAAAAGCAAAGAAAAAAAAAAAAAA AAAAAAA 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for BC015915 unedited AAAGAAGCTCGGGTTTTGTAACCGACTTACTTNGGGCGGCCGCGCATTCGGCACGAGGAC TCGCGGCCGGCGATGCGGGACCCCGGCGCGGCCGCTCCGCTTTCGTCCCTGGGCCTCTGT GCCCTGGTGCTGGCGCTGCTGGGCGCACTGTCCGCGGGCGCCGGGGCGCAGCCGTACCAC GGAGAGAAGGGCATCTCCGTGCCGGACCACGGCTTCTGCCAGCCCATCTCCATCCCGCTG TGCACGGACATCGCCTACAACCAGACCATCCTGCCCAACCTGCTGGGCCACACGAACCAA GAGGACGCGGGCCTCGAGGTGCACCAGTTCTACCCGCTGGTGAAGGTGCAGTGTTCTCCC GAACTCCGCTTTTTCTTATGCTCCATGTATGCGCCCGTGTGCACCGTGCTCGATCAGGCC ATCCCGCCGTGTCGTTCTCTGTGCGAGCGCGCCCGCCAGGGCTGCGAGGCGCTCATGAAC AAGTTCGGCTTCCAGTGGCCCGAGCGGCTGCGCTGCGAGAACTTCCCGGTGCACGGTGCG GGCGAGATCTGCGTGGGCCAGAACACGTCGGACGGCTCCGGGGGCCCATGCGGCGGCCCC ACTGCCTACCCTACCGCGCCCTACCTGCCGGACCTGCCCTTCACCGCGCTGCCCCCGGGG GCCTCAGATGGCAGGGGGCGTCCCGCCTTCCCCTTCTCATGCCCCCGTCAGCTCAAGGTG CCCCCGTACCTGGGCTACCGCTTCCTGGGTGAGCGCGATTGTGGCGCCCCGTGCGAACCG GGCCGTGCCAACGGCCTGATGTACTTTAAGGAGGAGAGAGGCGCTTCGGCCGCCTCTGGG TGGGGCGTGTGGTGCCGTGCTGTGCTGCGCCCTCGACGCTCTTTACCA
Restriction Sites	Please inquire
ACCN	BC015915
Insert Size	3100 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	BC015915.1, AAH15915.1
RefSeq Size	3067 bp
RefSeq ORF	1722 bp
Locus ID	8324
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Basal cell carcinoma, Colorectal cancer, Melanogenesis, Pathways in cancer, Wnt signaling pathway
Gene Summary	Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (4)

The use of this cDNA Clones has been cited in the following citations:
Serelaxin alleviates cardiac fibrosis through inhibiting endothelial-to-mesenchymal transition via RXFP1 ,null, Theranostics ,PubMed ID 32226528 [FZD7]
Long non-coding RNA DSCR8 acts as a molecular sponge for miR-485-5p to activate Wnt/β-catenin signal pathway in hepatocellular carcinoma ,null, Cell Death & Disease ,PubMed ID 30154476 [FZD7]
Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families ,null, The FASEB Journal ,PubMed ID 28733458 [FZD7]
FZD7 has a critical role in cell proliferation in triple negative breast cancer. ,null, Oncogene ,PubMed ID 21532620 [FZD7]

Documents

Product Manuals
TrueORFs: Open Reading Frame Clones - 10 ug in PrecisionShuttle Vector System pLenti-ORF destination vector Transfection - TurboFectin 8.0 Transfection Reagent Plasmid Preparation - PowerPrep Plasmid Purification Kits
FAQs
TrueORF Clones/PrecisionShuttle Organelle Marker Transfection Reagent
SDS
TrueORF SDS

Resources

cDNA 克隆相关资源
Video Tutorial: Clone Selection Guide Product Video: What is TrueORF GOLD and why it is the most popular type of clone Video Tutorial: How to make Lentivirus particles Video Tutorial: Is the Lentivirus Safe Product Brochure: cDNA clones $98 Clones. Download the List of 15,000 Protocol: Lentivirus packaging

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Expression Plasmids

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Proteins

Antibodies