SETMAR (BC008931) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	METNASE; SET domain and mariner transposase fusion; SET domain and mariner transposase fusion gene
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for BC008931 edited GGCACGAGGGGCAAAGACGACACGGCCTTGTGGGATGGCGGAGTTTAAGGAGAAGCCTGA GGCCCCGACTGAGCAGCTGGATGTCGCGTGCGGCCAGGAAAACTTGCCGGTGGGCGCGTG GCCCCCGGGGGCCGCGCCGGCGCCCTTCCAGTTCTCTGTACTGCCCCGTAGAAAAGTCGA ACATCAGTTGTGGAAATGAGAAGGAACCCAGCATGTGTGGCTCAGCCCCTTCTGTGTTCC CCTCCTGCAAGCGATTGACCCTTGAGACTATGAAAATGATGTTAGACAAAAAGCAAATTC GAGCAATTTTCTTATTCGAGTTCAAAATGGGTCGTAAAGCAGCAGAAACAACTCGCAACA TCAACAATGCATTTGGCCCAGGAACTGCTAACGAACGTACAGTGCAGTGGTGGTTCAAGA AGTTTTGCAAAGGAGATGAGAGCCTTGAAGATGAGGAGCGTAGTGGCCGGCCATCAGAAG TTGACAACGACCAGTTGAGAGCAATCATCGAAGCTGATCCCCTTACAACTACACGAGAAG TTGCTGAAGAACTCAATGTCAACCATTCTACGGTCGTTCGACATTTGAAGCAAATTGGAA AGGTGAAAAAGCTCGATAAGTGGGTGCCTCATGAGCTGACTGAAAATCAAAAAAATCGTC GTTTTGAAGTGTCATCTTCTCTTATTCTACGCAACCACAACGAACCATTTCTCGATCGGA TTGTGACGTGTGATGAAAAGTGGATTTTATATGACAACCGGCGACGATCAGCTCAGTGGT TGGATCAAGAAGAAGCTCCAAAGCACTTCCCAAAGCCAATCTTGCACCCAAAAAAGGTCA TGGTCACTATTTGGTGGTCTGCTGCTGGTCTGATCCACTACAGCTTTCTGAATCCCGGTG AAACCATTACATCTGAGAAGTATGCTCAGGAAATCGATGAGATGAACCAAAAACTGCAAC GCCTGCAGCTGGCATTGGTCAACAGAAAGGGCCCAATTCTTCTCCACGACAATGCCCGAC CGCATGTTGCACAACCCACACTTCAAAAGTTGAATGAATTGGGCTATGAAGTTTTGCCTC ATCCACCGTATTCACCTGACCTCTTGCCAACCAACTACCACGTCTTTAAGCATCTCAACA ACTTTTTGCAGGGAAAACGCTTCCACAACCAGCAGGATGCAGAAAATGCTTTCCAAGAGT TCGTCGAATCCCAAAGCACGGATTTTTACGCTACAGGAATAAACCAACTTATTTCTCGTT GGCAAAAATGTGTTGATTGTAATGGTTCCTATTTTGATTAATAAAAATGCGTTGAGCCTA AAAAAAAAAAAAAAAAAA 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for BC008931 unedited TCAGAATTTGTAATACGACTCTACTATAGGCGGCCGACGAATTCGCACGAGGGCAAAGAC GATACGGCCTTGTGGGATGGCGGAGTTTAAGGAGAAGCCTGAGGCCCCGACTGAGCAGCT GGATGTCGCGTGCGGCCAGGAAAACTTGCCGGTGGGCGCGTGGCCCCCGGGGGCCGCGCC GGCGCCCTTCCAGTTCTCTGTACTGCCCCGTATAAAAGTCGAACATCAGTTGTGGAAATG AGAAGGAACCCAGCATGTGTGGCTCAGCCCCTTCTGTGTTCCCCTCCTGCAAGCGATTGA CCCTTGAGACTATGAAAATGATGTTAGACAAAAAGCAAATTCGAGCAATTTTCTTATTCG AGTTCAAAATGGGTCGTAAAGCAGCAGAAACAACTCGCAACATCAACAATGCATTTGGCC CAGGAACTGCTAACGAACGTACAGTGCAGTGGTGGTTCAAGAAGTTTTGCAAAGGAGATG AGAGCCTTGAAGATGAGGAGCGTAGTGGCCGGCCATCAGAAGTTGACAACGACCAGTTGA GAGCAATCATCGAAGCTGATCCCCTTACAACTACACGAGAAGTTGCTGAAGAACTCAATG TCAACCATTCTACGGTCGTTCGACATTTGAAGCANATTGGANAGGTGAAAAAGCTCGATA AGTGGGTGCCTCATGAGCTGACTGAGAATCANANAAATCGTCGTTTTGAAGTGTCATCTT CTCTTATTCTACGCAACCACAACGAACCATTTCTCGATCGGATTGTGACGTGTGATGAAA AGTGGATTTATATGACAACCGGCGACGATCAGCTCANTGGTTGGATCAAGAAGAAGCTGC AAGCACTTCCNNAACCNNATCTGCACCCAAAAAAGTCATGGTCACTATTTNGTGGTCTGC TGCTGGTCTGATCACTACANCTTTCTGAATCCGGTGAAACCATACTCTGAGAAT
Restriction Sites	Please inquire
ACCN	BC008931
Insert Size	1338 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	BC008931.1, AAH08931.1
RefSeq Size	1338 bp
Locus ID	6419
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	Lysine degradation
Gene Summary	This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

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