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CACNB1 (NM_000723) Human Untagged Clone
CAT＃: SC123891
CACNB1 (untagged)-Human calcium channel, voltage-dependent, beta 1 subunit (CACNB1), transcript variant 1
CNY 4,464.00
CNY 7,220.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CAB1; CACNLB1; CCHLB1 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_000723, the custom clone sequence may differ by one or more nucleotides
ATGGTCCAGAAGACCAGCATGTCCCGGGGCCCTTACCCACCCTCCCAGGAGATCCCCATGGAGGTCTTCG ACCCCAGCCCGCAGGGCAAATACAGCAAGAGGAAAGGGCGATTCAAACGGTCAGATGGGAGCACGTCCTC GGATACCACATCCAACAGCTTTGTCCGCCAGGGCTCAGCGGAGTCCTACACCAGCCGTCCATCAGACTCT GATGTATCTCTGGAGGAGGACCGGGAAGCCTTAAGGAAGGAAGCAGAGCGCCAGGCATTAGCGCAGCTCG AGAAGGCCAAGACCAAGCCAGTGGCATTTGCTGTGCGGACAAATGTTGGCTACAATCCGTCTCCAGGGGA TGAGGTGCCTGTGCAGGGAGTGGCCATCACCTTCGAGCCCAAAGACTTCCTGCACATCAAGGAGAAATAC AATAATGACTGGTGGATCGGGCGGCTGGTGAAGGAGGGCTGTGAGGTTGGCTTCATTCCCAGCCCCGTCA AACTGGACAGCCTTCGCCTGCTGCAGGAACAGAAGCTGCGCCAGAACCGCCTCGGCTCCAGCAAATCAGG CGATAACTCCAGTTCCAGTCTGGGAGATGTGGTGACTGGCACCCGCCGCCCCACACCCCCTGCCAGTGCC AAACAGAAGCAGAAGTCGACAGAGCATGTGCCCCCCTATGACGTGGTGCCTTCCATGAGGCCCATCATCC TGGTGGGACCGTCGCTCAAGGGCTACGAGGTTACAGACATGATGCAGAAAGCTTTATTTGACTTCTTGAA GCATCGGTTTGATGGCAGGATCTCCATCACTCGTGTGACGGCAGATATTTCCCTGGCTAAGCGCTCAGTT CTCAACAACCCCAGCAAACACATCATCATTGAGCGCTCCAACACACGCTCCAGCCTGGCTGAGGTGCAGA GTGAAATCGAGCGAATCTTCGAGCTGGCCCGGACCCTTCAGTTGGTCGCTCTGGATGCTGACACCATCAA TCACCCAGCCCAGCTGTCCAAGACCTCGCTGGCCCCCATCATTGTTTACATCAAGATCACCTCTCCCAAG GTACTTCAAAGGCTCATCAAGTCCCGAGGAAAGTCTCAGTCCAAACACCTCAATGTCCAAATAGCGGCCT CGGAAAAGCTGGCACAGTGCCCCCCTGAAATGTTTGACATCATCCTGGATGAGAACCAATTGGAGGATGC CTGCGAGCATCTGGCGGAGTACTTGGAAGCCTATTGGAAGGCCACACACCCGCCCAGCAGCACGCCACCC AATCCGCTGCTGAACCGCACCATGGCTACCGCAGCCCTGGCTGCCAGCCCTGCCCCTGTCTCCAACCTCC AGGGACCCTACCTTGCTTCCGGGGACCAGCCACTGGAACGGGCCACCGGGGAGCACGCCAGCATGCACGA GTACCCAGGGGAGCTGGGCCAGCCCCCAGGCCTTTACCCCAGCAGCCACCCACCAGGCCGGGCAGGCACG CTACGGGCACTGTCCCGCCAAGACACTTTTGATGCCGACACCCCCGGCAGCCGAAACTCTGCCTACACGG AGCTGGGAGACTCATGTGTGGACATGGAGACTGACCCCTCAGAGGGGCCAGGGCTTGGAGACCCTGCAGG GGGCGGCACGCCCCCAGCCCGACAGGGATCCTGGGAGGACGAGGAAGAAGACTATGAGGAAGAGCTGACC GACAACCGGAACCGGGGCCGGAATAAGGCCCGCTACTGCGCTGAGGGTGGGGGTCCAGTTTTGGGGCGCA ACAAGAATGAGCTGGAGGGCTGGGGACGAGGCGTCTACATTCGCTGA >OriGene 5' read for NM_000723 unedited
TACGACTGACTATAGGGCGGCCGCGAATTCGGCGCGAGGGGCAGCCGAAGGCCGAGCTGG GTGGCTGGACCGGGTGCTGGCTGCGCCGCGCTGCTTTCGGCTCCCACGGCCGCTCCCATG CGCTGAGGGAGCCCGGCTGGGCCGGGCCGGCGGCGGGAGGGGAGGCTCCTCTCCATGGTC CAGAAGACCAGCATGTCCCGGGGCCCTTACCCACCCTCCCAGGAGATCCCCATGGAGGTC TTCGACCCCAGCCCGCAGGGCAAATACAGCAAGAGGAAAGGGCGATTCAAACGGTCAGAT GGGAGCACGTCCTCGGATACCACATCCAACAGCTTTGTCCGCCAGGGCTCAGCGGAGTCC TACACCAGCCGTCCATCAGACTCTGATGTATCTCTGGAGGAGGACCGGGAAGCCTTAAGG AAGGAAGCAGAGCGCCAGGCATTAGCGCAGCTCGAGAAGGCCAAGACCAAGCCAGTGGCA TTTGCTGTGCGGACAAATGTTGGCTACAATCCGTCTCCAGGGGATGAGGTGCCTGTGCAG GGAGTGGCCATCACCTTCGAGCCCAAAGACTTCCTGCACATCAAGGAGAAATACANTAAT GACTGGTGGATCGGNCNGCTGGTGAANGAGGGCTGTGAGGTTGCTTCATTTCCAGCCCGT CAACTGACAGCCTCGCTGCTGANGACAGAACTGCGCAGACCNGCTCGCTCAGCAATCAGC GATACTCAGNTCAGTCTGGAGAGTGTGCTGCAN >OriGene 3' read for NM_000723 unedited
CCCGGCCAGGAGAGGCACTGGGGAGGGGTCACAGGGATGCCACCCGGGATCTGTTCAGGA AACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTGGTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGCAAAGGCCTTTGAAAGGGGGGAGTCAG CCCCCCCTGGAGGCGAATACATGTCAGGTGTGAGCCCCTTGCTTCCTCCCCTTCCCTGGG CTTAAAGCCCTTCCTCCCGCCGTGTGGCCCCTGCCTTTTAACGAATGTAAACGCCTTGTC CCCAGCCCTCCAGCTTATTTTTGTTGCGCCCCAAAACTGGACCCCCACCCTCAGCGCAAT AGCGGGCCTTATTCCGGCCCCGGTTCCGGTTGTCGGTCAACTCTTCCTCATAGTCTTCTT CCTCGTCCTCCCAAGATCCCTGTCGGGCTGGGGGCGTGCCGCCCCCTGGAGGGTCTCCAA GCCCTGGCCCCTCTGAGGGGTCAGTCTCCATGTCCACACATGAGTCTCCCAGCTCCGTGT AAGCAAAATTTCCGCTGCCGGGGGTGTCGGCATCAAAAGTGTCTTGGCGGGACAATGCCC GTATCGTGCCTGCCCGGCCTGGTGGGTGGCTTCTGGGGTAAAAGCCTGGGGGCTTGCCCA ACTCCCCTGGTACCTGTGCATGGTGGGGTGCTCCCCGTGTGCCCTTTCATGGCTGGTCCC CGGAACAAAGTTAGGCCCCTGGGGTTTGAAAACAGGCCAGGCTTTT |
| Restriction Sites | Please inquire |
| ACCN | NM_000723 |
| Insert Size | 2500 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | A TrueClone. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000723.3, NP_000714.3 |
| RefSeq Size | 3687 bp |
| RefSeq ORF | 1797 bp |
| Locus ID | 782 |
| UniProt ID | Q02641 |
| Domains | Ca_channel_B, SH3, GuKc |
| Protein Families | Druggable Genome, Ion Channels: Other |
| Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway |
| Gene Summary | The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1), also known as beta-1b2, betaA, and beta-1B, encodes the longest isoform (1). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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The ß1 Subunit of L-Type Voltage-Gated Ca2+ Channels Independently Binds to and Inhibits the Gating of Large-Conductance Ca2+-Activated K+ Channels
,Shengwei Zou, Smita Jha, Eun Young Kim, and Stuart E. Dryer,
Mol. Pharmacol., Feb 2008; 73: 369 - 378.
[CACNB1]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207230 | CACNB1 (Myc-DDK-tagged)-Human calcium channel, voltage-dependent, beta 1 subunit (CACNB1), transcript variant 1 |
CNY 3,990.00 |
|
| RC207230L1 | Lenti ORF clone of Human calcium channel, voltage-dependent, beta 1 subunit (CACNB1), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC207230L2 | Lenti ORF clone of Human calcium channel, voltage-dependent, beta 1 subunit (CACNB1), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC207230L3 | Lenti ORF clone of Human calcium channel, voltage-dependent, beta 1 subunit (CACNB1), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC207230L4 | Lenti ORF clone of Human calcium channel, voltage-dependent, beta 1 subunit (CACNB1), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG207230 | CACNB1 (tGFP-tagged) - Human calcium channel, voltage-dependent, beta 1 subunit (CACNB1), transcript variant 1 |
CNY 4,370.00 |
