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COX8A (NM_004074) Human Untagged Clone
CAT＃: SC126992
COX8A (untagged)-Human cytochrome c oxidase subunit VIIIA (ubiquitous) (COX8A)
CNY 1,800.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | COX; COX8; COX8-2; COX8L; MC4DN15; VIII; VIII-L |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC126992 sequence for NM_004074 edited (data generated by NextGen Sequencing)
ATGTCCGTCCTGACGCCGCTGCTGCTGCGGGGCTTGACAGGCTCGGCCCGGCGGCTCCCA GTGCCGCGCGCCAAGATCCATTCGTTGCCGCCGGAGGGGAAGCTTGGGATCATGGAATTG GCCGTTGGGCTTACCTCCTGCTTCGTGACCTTCCTCCTGCCAGCGGGCTGGATCCTGTCA CACCTGGAGACCTACAGGAGGCCAGAGTGA Clone variation with respect to NM_004074.2 >OriGene 5' read for NM_004074 unedited
TTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCTTGGGCTACGGC TGACCGTTTTTTGTGGTGTACTCCGTGCCATCATGTCCGTCCTGACGCCGCTGCTGCTGC GGGGCTTGACAGGCTCGGCCCGGCGGCTCCCAGTGCCGCGCGCCAAGATCCATTCGTTGC CGCCGGAGGGGAAGCTTGGGATCATGGAATTGGCCGTTGGGCTTACCTCCTGCTTCGTGA CCTTCCTCCTGCCAGCGGGCTGGATCCTGTCACACCTGGAGACCTACAGGAGGCCAGAGT GAAGGGGTCCGTTCTGTCCCTCACACTGTGACCTGACCAGCCCCACCGGCCCATCCTGGT CATGTTACTGCATTTGTGGCCGGCCTCCCCTGGATCATGTCATTCAATTCCAGTCACCTC TTCTGCAATCATGACCTCTTGATGTCTCCATGGTGACCTCCTTGGGGGTCACTGACCCTG CTTGGTGGGGTCCCCCTTGTAACAATAAAATCTATTTAAACTTTAAAAAAAAAAAAAAAA AAAAAACTCGACTCTAGATTGCGGCCGCGGTCATAGCTGTTTCCTGAACAGATCCCGGGT GGCATCCCTGTGACCCCTCCCCAGTGCCTCTCCTGGCCCCTGGAGTTGCCACTCCAGTGC CCACCAGCCTTGTCCTAATAAAATTAAGTTGCATCATTTTGTCTGACTAGGTGTCCTTCT ATAATATTATGGGGTGGAGGGGGGTTGGTATTGGACCCAGGGGCCAAAGTGGGAAAGACA ACCTGTAGGGCCTGCGGTGTTCTATTGGGAACCAAGCTGAAGGGCAGGGGCACAATCTTG GTTACTGGAATCCCGCCTTCTGGTTAAAGCGATCTCCTGCCTCACCTCCCCAGTGTCGGG T >OriGene 3' read for NM_004074 unedited
GTAACGCGGCCCGCTCTCTAGTATCGAGTTTTTTTCTTTTTTTTTTTTTTAAAGTTTAAA TAGATTTTATTGTTACAAGGGGGACCCCACCAAGCAGGGTCAGTGACCCCCAAGGAGGTC ACCATGGAGACATCAAGAGGTCATGATTGCAGAAGAGGTGACTGGAATTGAATGACATGA TCCAGGGGAGGCCGGCCACAAATGCAGTAACATGACCAGGATGGGCCGGTGGGGCTGGTC AGGTCACAGTGTGAGGGACAGAACGGACCCCTTCACTCTGGCCTTCTGTAGGTCTCCAGG TGTGACAGGATCCAGCCCGCTGGCAGGAGGAAGGTCACGAAGCAGGAGGTAAGCCCAACG GCCAATTTCATGATCCCAAGCTTACCCTCCGGCGGTAACGAATGGATCTTGGCGCGCGGT ACTGGGAGCCGTCGGTCCGAGCCTGTTAAGCCCCGTATCATTAGCGGCGTTAGGACGGAC ATGATGGCACGGAGTACACCACAAAAAACGGTTAGTCCGTACCCCAAGGCCTCGTGCCGA ATTCGCGGCCGTCCTATAGTGAGCCCTATTACAAAATTCTGACGGTTCACTAAACGAGCT CTGCTTATATAGACCTACAACCGTACACGCCTACCGCACATTTTGCGATAACGGGGCCGA GGTTATTACCACATTTTGAAAAAGCCTCGTTGTTTTTGGTGCCAAAACAAACTTCCATTG ACGTCTATGGGGCGGGAAACTTGGAAATCTCCGTGAGTTAAACCGCTATACACGCCCATT GGTGTACTGGTCATATCCGCTTACTTTGGGAATAGCGAGGACTATTACCTATATGTCCTG CCAATTAGAAAGCCCGTAAGGCCTGTCCTGGTTTATGCCAGGGGGCCATTTACCGCCTTG ACATATAAGGGGCGACTCTGCTTATATTCACTTGAGTCTGCCAATGGACATTTCCCTATA TCTCACCTCTGCGCCTAGGAAGTCCCATGGGGTTCTTGGCACTCACTACTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004074 |
| Insert Size | 510 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_004074.2, NP_004065.1 |
| RefSeq Size | 521 bp |
| RefSeq ORF | 210 bp |
| Locus ID | 1351 |
| UniProt ID | P10176 |
| Domains | COX8 |
| Protein Families | Transmembrane |
| Protein Pathways | Alzheimer's disease, Cardiac muscle contraction, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease |
| Gene Summary | The protein encoded by this gene is the terminal enzyme of the respiratory chain, coupling the transfer of electrons from cytochrome c to molecular oxygen, with the concomitant production of a proton electrochemical gradient across the inner mitochondrial membrane. In addition to 3 mitochondrially encoded subunits, which perform the catalytic function, the eukaryotic enzyme contains nuclear-encoded smaller subunits, ranging in number from 4 in some organisms to 10 in mammals. It has been proposed that nuclear-encoded subunits may be involved in the modulation of the catalytic function. This gene encodes one of the nuclear-encoded subunits. [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Confined activation and subdiffractive localization enables whole-cell PALM with genetically expressed probes
,Andrew G York, Alireza Ghitani, Alipasha Vaziri, Michael W Davidson, Hari Shroff,
Nature Methods (13 February 2011) doi:10.1038/nmeth.1571 Article
[COX8A]
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| RC209065L4 | Lenti ORF clone of Human cytochrome c oxidase subunit VIIIA (ubiquitous) (COX8A), mGFP tagged |
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| RG209065 | COX8A (tGFP-tagged) - Human cytochrome c oxidase subunit VIIIA (ubiquitous) (COX8A) |
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