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CTBP2 (NM_001329) Human Untagged Clone
CAT＃: SC127174
CTBP2 (untagged)-Human C-terminal binding protein 2 (CTBP2), transcript variant 1
CNY 3,656.00
CNY 7,130.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC127174 sequence for NM_001329 edited (data generated by NextGen Sequencing)
ATGGCCCTTGTGGATAAGCACAAAGTCAAGAGACAGCGATTGGACAGAATTTGTGAAGGT ATCCGCCCCCAGATCATGAACGGCCCCCTGCACCCCCGCCCCCTGGTGGCGCTGCTGGAC GGCCGCGACTGCACTGTGGAGATGCCCATCCTGAAGGACCTGGCCACTGTGGCCTTCTGT GACGCGCAGTCGACGCAGGAAATCCACGAGAAGGTTCTAAACGAAGCCGTGGGCGCCATG ATGTACCACACCATCACCCTCACCAGGGAGGACCTGGAGAAGTTCAAGGCCCTGAGAGTG ATCGTGCGGATAGGCAGTGGCTATGACAACGTGGACATCAAGGCTGCCGGCGAGCTCGGA ATTGCCGTGTGCAACATCCCGTCTGCAGCCGTGGAAGAGACAGCGGACTCTACCATCTGC CACATCCTCAACCTGTACCGGAGGAACACGTGGCTGTACCAGGCACTGCGGGAAGGCACG CGGGTTCAGAGCGTGGAGCAGATCCGCGAGGTGGCCTCGGGAGCGGCCCGCATCCGTGGG GAGACGCTGGGCCTCATTGGCTTTGGTCGCACGGGGCAGGCGGTTGCAGTTCGAGCCAAG GCCTTTGGATTCAGCGTCATATTTTATGACCCCTACTTGCAGGATGGGATCGAGCGGTCC CTGGGCGTGCAGAGGGTCTACACCCTGCAGGATTTGCTGTATCAGAGCGACTGCGTCTCC TTGCACTGCAATCTCAACGAACATAACCACCACCTCATCAATGACTTTACCATAAAGCAG ATGAGGCAGGGAGCATTCCTTGTGAACGCAGCCCGTGGCGGCCTGGTGGACGAGAAAGCC TTAGCACAAGCCCTCAAGGAGGGCAGGATACGAGGGGCAGCCCTCGACGTGCATGAGTCA GAGCCCTTCAGCTTTGCTCAGGGTCCGTTGAAAGATGCCCCGAATCTCATCTGCACTCCT CACACTGCCTGGTACAGTGAGCAGGCGTCACTGGAGATGAGGGAGGCAGCTGCCACCGAG ATCCGCCGAGCCATCACAGGTCGCATCCCAGAAAGCTTAAGAAATTGTGTGAACAAGGAA TTCTTTGTCACATCAGCGCCTTGGTCAGTAATAGACCAGCAAGCAATTCATCCTGAGCTC AATGGTGCCACATACAGATATCCGCCAGGCATCGTGGGTGTGGCTCCAGGAGGACTTCCT GCAGCCATGGAAGGGATCATCCCTGGAGGCATCCCAGTGACTCACAACCTCCCGACAGTG GCACATCCTTCCCAAGCGCCCTCTCCCAACCAGCCCACAAAACACGGGGACAATCGAGAG CACCCCAACGAGCAATAG Clone variation with respect to NM_001329.2 >OriGene 5' read for NM_001329 unedited
TAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGAAGTTTTTGTGTGTGTGT CCCTGTGTGCGTGTGTCATTTTAAGGTGGCTCGGGAGCGGCCCGGAGGAGCCGGCGGCGG CCCGAGGAGCGAGGGACCGAACCGGGAGCCATGCCGCGCTGAGGGGGGGCCGCACAGCCG CCGCCACCGCCACCGCCGCCGGGTGGGGTGGGAGGGGGCGGGAGACGCCGCCGCCGCCGC CTCCAGGGTGGGCGCCTTTCGCCGTGGACGCCGACCGTCCGGGACGAGGGTTTCATCACC TTAAATGGTTTTGAACCAATGAAGGTGTATTCCCTTAAAAAGACGGACAGCCCATCGTGT GAACTATAGAGTTTGTGGACAGATTTATATTGGGTTCATAGTGGCGTCATGCACGCAGAC TCCTGCAAGTTCCCCTAAGTTCTTAGAGGACTGCTTTGCCTTTTGATCTGAGAGTTGCAA AGTTCCATAAAGAATGGCCCTTGTGGATAAGCACAAAGTCAAGAGACAGCGATTGGACAG AATTGTGAAGGGNTTATCCGCCCNCAGATCATGAACGGCCCCCTGCACCCCCGCCCCCTG GTGGCGCTGNTGGNACGGCCGCGACTGCACTGTGGGNAGATGCCNCATCCTGAAGACCTG GCCACTGTGGCCTTCTGTGACGCGCAGTCGACGCAGGAATCCCGNAAAAGGTTCTAACGA AGGCCGTGGCGCCATGATGTACACACCATCACCTACNAAGGGAGCTGGNNNAAAATTCAG GCCTGAGAAAGGATCGTGCGATAGGCAGTGCTATGACAACGTGACATCAGGCTGNCGCGA GCTCGAATGGCGTGGCACATCCGTTGAGCGGGGGAAAAACAGGGACCTACATTGCCATCT CACTTACCGAGGACCCGGGTGACAGCTGGGAG >OriGene 3' read for NM_001329 unedited
GACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGCATCATCAGAGGGTT TTACTGAACTTACAACCGACTTGCCCGCTCAGTATGCAGTTCAGATGTGAGAGGCGCTTC TCTGTACAGCAGCCTGTACTGTCTTCAATCCTATGCGTGCAGGTGTCTACCACAGGCAAA CAGTTTTCTCCCCATTTTGTAGTAATGTGATTTTCCTATTAGCAAAAAGAGGTCACCAGC CCCTGTAGACTTAAGGGACTCAAGTCACAGGATGGGGATTTCCTCTTAATATTTTTTATT TTGTTGTTTGAACTCTTGATGCAACATTGTAGAGCAGGGTGTTCAGGACCTGCTGTGCCC AAGGGACTGATAAAGGAAAAAGCTCTATTTATTCTTTTTGTGATTTGATGCACAGATGAA AAACTTAACACACAATAACAGAAGTTGGTCGTTAATAAATCACATCCTAGTCTTTCAGCG CTTCCGTAAGCAGACGACATCTTCAGTTTTCTAGCTCTTGTAGTTTCAACACTGCAACAT CAATGATGCATATGTCCAGAATCAGTTACAAAGACCATCCGATTCTTTTTCTCTTAGTTC ATCTATTTTTCACTGTCTCTTGGTCCCAAGTGTATCTGAGTGATTACCTTCTGGCATTCT CTGCTATTGCTCGTTGGGGTGCTCTCGATTGTCCCCGTGTTTTGTGGGCTGGTTGGGAGA GGGCGCTNTGGAANGATGTGCCACTGTCGGGAAGGTGTGAGTCACTGGGATGCCTNCAGG GATGATCCCTTCCATGGCTGCANGAAGTNCTNCTGGAGCCACACCCACGATGCCNNTGCG ATATCTGTATGTGGNCACCATTGAGCTCANGATGAAATNNGCTGCTGGNCTATTACTGAC CAAGCGGCTGATGTGACAAAGAATTCCTTTGTCACACATTNCTTAGCTTNCTGGATGCGA CCTGTGATGGCTCGCGGATCTCGTGGANNTGCTNNCTCATTCATGACGCTGCTACTGTCC AGCNGGTNAGAAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001329 |
| Insert Size | 2660 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001329.1, NP_001320.1 |
| RefSeq Size | 2368 bp |
| RefSeq ORF | 1338 bp |
| Locus ID | 1488 |
| UniProt ID | P56545 |
| Domains | 2-Hacid_DH, 2-Hacid_DH_C |
| Protein Families | Stem cell - Pluripotency, Stem cell relevant signaling - Wnt Signaling pathway |
| Protein Pathways | Chronic myeloid leukemia, Notch signaling pathway, Pathways in cancer, Wnt signaling pathway |
| Gene Summary | This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2014] Transcript Variant: This variant (1) contains a distinct 5' UTR and 5' CDS, compared to variant 2. Variants 1, 3, 4, and 5-8 all encode the same isoform (1), which has a distinct N-terminus that is 540 aa shorter than the N-terminus of isoform 2. The protein is thought to bind to the C-terminus of the adenovirus E1A proteins. Studies in mice suggest that this protein is involved in transcriptional repression. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
C-terminal binding protein-2 regulates response of epithelial ovarian cancer cells to histone deacetylase inhibitors
,L Barroilhet, J Yang, K Hasselblatt, R M Paranal, S-K Ng, J A Rauh-Hain, W R Welch, J E Bradner, R S Berkowitz & S-W Ng,
Oncogene doi:10.1038/onc.2012.380
[CTBP2]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC224861 | CTBP2 (Myc-DDK-tagged)-Human C-terminal binding protein 2 (CTBP2), transcript variant 1 |
CNY 3,656.00 |
|
| RC224861L1 | Lenti ORF clone of Human C-terminal binding protein 2 (CTBP2), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC224861L2 | Lenti ORF clone of Human C-terminal binding protein 2 (CTBP2), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC224861L3 | Lenti ORF clone of Human C-terminal binding protein 2 (CTBP2), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC224861L4 | Lenti ORF clone of Human C-terminal binding protein 2 (CTBP2), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG224861 | CTBP2 (tGFP-tagged) - Human C-terminal binding protein 2 (CTBP2), transcript variant 1 |
CNY 4,370.00 |
