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NSD1 (NM_022455) Human Untagged Clone
CAT＃: SC309685
NSD1 (untagged)-Human nuclear receptor binding SET domain protein 1 (NSD1), transcript variant 2
CNY 51,870.00
货期*
2周
规格
Product images
经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ARA267; KMT3B; SOTOS; SOTOS1; STO |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_022455 edited
GAGAGAGAGAGATCCAGCTGCTCGACCCCTGGCGAGGGAGGGGGAGGACTAGTCCTGTTT GAGAATTGGGAATTTTGACGGGCAGAGGGGTTTTAATTTTAGTTCATCCCAAGTGTCCAC CAGTCTACAGAGGAGGAAAAAGAGACGGGCTGTTTCTATGTAGCAGGATCGGCCCAGCTT CGGGAAAATGGAGTTTTCAGAGGCTCATCGAGGCCATTTTTTCATCTCCAGTCGGGGGAA CTTTTTCTGCCCATGGAAGTGCAGCAGAAAGGCATAGAGGCCACTAGGCCTTGAAGTGGC TGCCATTTTAAAGAGTCGAGTCAGATGGCCTATTAACTCAGATTAATTGCTGTGCTTTTG GATTCCAGGTTGATGCCGGCCCAGGATGGATCAGACCTGTGAACTACCCAGAAGAAATTG TCTGCTGCCCTTTTCCAATCCAGTGAATTTAGATGCCCCTGAAGACAAGGACAGCCCTTT CGGTAATGGTCAATCCAATTTTTCTGAGCCACTTAATGGGTGTACTATGCAGTTATCGAC TGTCAGTGGAACATCCCAAAATGCTTATGGACAAGATTCTCCATCTTGTTACATTCCACT GCGGAGACTACAGGATTTGGCCTCCATGATCAATGTAGAGTATTTAAATGGGTCTGCTGA TGGATCAGAATCCTTTCAAGACCCTGAAAAAAGTGATTCAAGAGCTCAGACGCCAATTGT TTGCACTTCCTTGAGTCCTGGTGGTCCTACAGCACTTGCTATGAAACAGGAACCCTCTTG TAATAACTCCCCTGAACTCCAGGTAAAAGTAACAAAGACTATCAAGAATGGCTTTCTGCA CTTTGAGAATTTTACTTGTGTGGACGATGCAGATGTAGATTCTGAAATGGACCCAGAACA GCCAGTCACAGAGGATGAGAGTATAGAGGAGATCTTTGAGGAAACTCAGACCAATGCCAC CTGCAATTATGAGACTAAATCAGAGAATGGTGTAAAAGTGGCCATGGGAAGTGAACAAGA CAGCACACCAGAGAGTAGACACGGTGCAGTCAAATCGCCATTCTTGCCATTAGCTCCTCA GACTGAAACACAGAAAAATAAGCAAAGAAATGAAGTGGACGGCAGCAATGAAAAAGCAGC CCTTCTCCCAGCCCCCTTTTCACTAGGAGACACAAACATTACAATAGAAGAGCAATTAAA CTCAATAAATTTATCTTTTCAGGATGATCCAGATTCCAGTACCAGTACATTAGGAAACAT GCTAGAATTACCTGGAACTTCATCATCATCTACTTCACAGGAATTGCCATTTTGTCAACC TAAGAAAAAGTCTACGCCACTGAAGTATGAAGTTGGAGATCTCATCTGGGCAAAATTCAA GAGACGCCCATGGTGGCCCTGCAGGATTTGTTCTGATCCGTTGATTAACACACATTCAAA AATGAAAGTTTCCAACCGGAGGCCCTATCGGCAGTACTACGTGGAGGCTTTTGGAGATCC TTCTGAGAGAGCCTGGGTGGCTGGAAAAGCAATCGTCATGTTTGAAGGCAGACATCAATT CGAAGAGCTACCTGTCCTTAGGAGAAGAGGGAAACAGAAAGAAAAAGGATATAGGCATAA GGTTCCTCAGAAAATTTTGAGTAAATGGGAAGCCAGTGTTGGACTTGCAGAACAGTATGA TGTTCCCAAGGGGTCAAAGAACCGAAAATGTATTCCTGGTTCAATCAAGTTGGACAGTGA AGAAGATATGCCATTTGAAGACTGCACAAATGATCCTGAGTCAGAACATGACCTGTTGCT TAATGGCTGTTTGAAATCACTGGCTTTTGATTCTGAACATTCTGCAGATGAGAAGGAAAA GCCTTGCGCTAAATCTCGAGCCAGAAAGAGCTCTGATAATCCAAAAAGGACTAGTGTGAA AAAGGGCCACATACAATTTGAAGCACATAAAGATGAACGGAGGGGAAAGATTCCAGAGAA CCTTGGCCTAAACTTTATCTCTGGGGATATATCTGATACGCAGGCCTCTAATGAACTTTC CAGGATAGCAAATAGCCTCACAGGGTCCAACACTGCCCCAGGAAGTTTTCTGTTTTCTTC CTGTGGAAAAAACACTGCAAAGAAAGAATTTGAGACTTCAAATGGTGACTCTTTATTGGG CTTGCCTGAGGGTGCTTTGATCTCAAAGTGTTCTCGAGAGAAGAATAAACCCCAACGAAG CCTGGTGTGTGGTTCAAAAGTGAAGCTCTGCTATATTGGAGCAGGTGATGAGGAAAAGCG AAGTGATTCCATTAGTATCTGTACCACTTCTGATGATGGAAGCAGTGACCTGGATCCCAT AGAACACAGCTCAGAGTCTGATAACAGTGTCCTTGAAATTCCAGATGCTTTCGATAGAAC AGAGAACATGTTATCTATGCAGAAAAATGAAAAGATAAAGTATTCTAGGTTTGCTGCCAC AAACACTAGGGTAAAAGCAAAACAGAAGCCTCTCATTAGTAACTCACATACAGACCACTT AATGGGTTGTACTAAGAGTGCAGAGCCTGGAACCGAGACGTCTCAGGTTAATCTCTCTGA TCTGAAGGCATCTACTCTTGTTCACAAACCCCAGTCAGATTTTACAAATGATGCTCTCTC TCCAAAATTCAACCTGTCATCAAGCATATCCAGTGAGAACTCGTTAATAAAGGGTGGGGC AGCAAATCAAGCTCTATTACATTCGAAAAGCAAACAGCCCAAGTTCCGAAGTATAAAGTG CAAACACAAAGAAAATCCAGTTATGGCAGAACCCCCAGTTATAAATGAGGAGTGCAGTTT GAAATGCTGCTCTTCTGATACCAAAGGCTCTCCTTTGGCCAGCATTTCTAAAAGTGGGAA AGTGGATGGTCTAAAACTACTGAACAATATGCATGAGAAAACCAGGGATTCAAGTGACAT AGAAACAGCAGTGGTGAAACATGTTTTATCCGAGTTGAAGGAACTCTCTTACAGATCCTT AGGTGAGGATGTCAGTGACTCTGGAACATCAAAGCCATCAAAACCATTACTTTTCTCTTC TGCTTCTAGTCAGAATCACATACCTATTGAACCAGACTACAAATTCAGTACATTGCTAAT GATGTTGAAAGATATGCATGATAGTAAGACGAAGGAGCAGCGGTTGATGACTGCTCAAAA CCTGGTCTCTTACCGGAGTCCTGGTCGTGGGGACTGTTCTACTAATAGTCCTGTAGGAGT CTCTAAGGTTTTGGTTTCAGGAGGCTCCACACACAATTCAGAGAAAAAGGGAGATGGCAC TCAGAACTCCGCCAATCCTAGCCCTAGTGGGGGTGACTCTGCATTATCTGGCGAGTTGTC TGCTTCCCTACCTGGCTTACTGTCCGACAAGAGAGACCTCCCTGCTTCTGGTAAAAGTCG TTCAGACTGTGTTACTAGGCGCAACTGTGGACGATCAAAGCCTTCATCCAAATTGCGAGA TGCTTTTTCAGCCCAAATGGTAAAGAACACAGTGAACCGTAAAGCCTTAAAGACCGAGCG CAAAAGAAAACTGAATCAGCTTCCAAGTGTGACTCTTGATGCTGTACTGCAGGGAGACCG AGAACGTGGAGGTTCATTGAGAGGTGGGGCAGAAGATCCTAGTAAAGAGGATCCCCTTCA GATAATGGGCCACTTAACAAGTGAAGATGGTGACCATTTTTCTGATGTGCATTTCGATAG CAAGGTTAAGCAATCTGATCCTGGTAAAATTTCTGAAAAAGGACTCTCTTTTGAAAACGG AAAAGGCCCAGAGCTGGACTCTGTAATGAACAGTGAGAATGATGAACTCAATGGTGTAAA TCAAGTGGTGCCTAAAAAGCGGTGGCAGCGTTTAAACCAAAGGCGCACTAAACCTCGTAA GCGCATGAACAGATTTAAAGAGAAAGAAAACTCTGAGTGTGCCTTTAGGGTCTTACTTCC TAGTGACCCTGTGCAGGAGGGGCGGGATGAGTTTCCAGAGCATAGAACTCCTTCAGCAAG CATACTTGAGGAACCACTGACAGAGCAAAATCATGCTGACTGCTTAGATTCAGCTGGGCC ACGGTTAAATGTTTGTGATAAATCCAGTGCCAGCATTGGTGACATGGAAAAGGAGCCAGG AATTCCCAGTTTGACACCACAGGCTGAGCTCCCTGAACCAGCTGTGCGGTCAGAGAAGAA ACGCCTTAGGAAGCCAAGCAAGTGGCTTTTGGAATATACAGAAGAATATGATCAGATATT TGCTCCTAAGAAAAAACAAAAGAAGGTACAGGAGCAGGTGCACAAGGTAAGTTCCCGCTG TGAAGAGGAAAGCCTTCTAGCCCGAGGTCGATCTAGTGCTCAGAACAAGCAGGTGGACGA GAATTCTTTGATTTCAACCAAAGAAGAGCCTCCAGTTCTTGAAAGGGAGGCTCCGTTTTT GGAGGGCCCCTTGGCTCAGTCAGAACTTGGAGGTGGACATGCTGAGTTGCCGCAGCTGAC CTTGTCTGTGCCTGTGGCTCCGGAAGTCTCTCCACGGCCTGCCCTTGAGTCTGAGGAATT GCTAGTTAAAACGCCAGGAAATTATGAAAGTAAACGTCAAAGAAAACCAACTAAGAAACT TCTTGAATCCAATGATTTAGACCCTGGATTTATGCCCAAGAAGGGGGACCTTGGCCTTTC TAAAAAGTGCTATGAAGCTGGTCACCTGGAGAATGGCATAACTGAATCTTGTGCCACATC TTATTCAAAAGATTTTGGTGGAGGCACTACCAAGATATTTGACAAGCCAAGGAAGCGAAA ACGACAGAGGCATGCTGCAGCCAAGATGCAGTGTAAAAAAGTGAAAAATGATGACTCGTC AAAAGAGATTCCAGGCTCAGAGGGAGAACTAATGCCTCACAGGACGGCCACAAGCCCCAA GGAGACTGTTGAGGAAGGTGTAGAACACGATCCCGGGATGCCTGCCTCTAAAAAAATGCA GGGTGAACGCGGTGGAGGAGCTGCACTCAAGGAGAATGTCTGTCAGAATTGTGAAAAATT GGGTGAGCTGCTGTTATGTGAGGCTCAGTGCTGTGGGGCTTTCCACCTGGAGTGCCTTGG ATTGACTGAGATGCCAAGAGGAAAATTTATCTGCAATGAATGTCGCACAGGAATCCATAC CTGTTTTGTATGTAAGCAGAGTGGGGAAGATGTTAAAAGGTGCCTTCTACCCTTGTGTGG AAAGTTTTACCATGAAGAGTGTGTCCAGAAGTACCCACCCACTGTTATGCAGAACAAGGG CTTCCGGTGCTCCCTCCACATCTGTATAACCTGTCATGCTGCTAATCCAGCCAATGTTTC TGCATCTAAAGGTCGGTTGATGCGCTGTGTCCGCTGTCCTGTGGCATACCACGCCAATGA CTTTTGCCTGGCTGCTGGGTCAAAGATCCTTGCATCTAATAGTATCATCTGCCCTAATCA CTTTACCCCTAGGCGGGGCTGCCGAAATCATGAGCATGTTAATGTTAGCTGGTGCTTTGT GTGCTCAGAAGGAGGCAGCCTTCTGTGCTGTGATTCTTGCCCTGCTGCTTTTCATCGTGA ATGCCTGAACATTGATATCCCTGAAGGAAACTGGTATTGCAATGACTGTAAAGCAGGCAA AAAGCCACACTACAGGGAGATTGTCTGGGTAAAAGTTGGACGATACAGGTGGTGGCCAGC TGAGATCTGCCATCCTCGAGCTGTTCCTTCCAACATTGATAAGATGAGACATGATGTGGG AGAGTTCCCAGTCCTCTTTTTTGGATCTAATGACTATTTGTGGACTCACCAGGCCCGAGT CTTCCCTTACATGGAGGGTGACGTGAGCAGCAAGGATAAGATGGGCAAAGGAGTGGATGG GACATATAAAAAAGCTCTTCAGGAAGCTGCAGCAAGGTTTGAGGAATTAAAGGCCCAAAA AGAGCTAAGACAGCTGCAGGAAGACCGAAAGAATGACAAGAAGCCACCACCTTATAAACA TATAAAGGTAAACCGTCCTATTGGCAGGGTACAGATCTTCACTGCAGACTTATCTGAAAT ACCCCGTTGCAACTGTAAAGCTACTGATGAGAACCCCTGTGGGATAGACTCTGAATGCAT CAACCGCATGCTGCTCTATGAGTGCCACCCCACAGTGTGTCCTGCCGGAGGGCGCTGTCA AAACCAGTGCTTTTCCAAGCGCCAATATCCAGAGGTTGAAATTTTCCGCACATTACAGCG GGGTTGGGGTCTACGGACAAAAACAGATATTAAAAAGGGTGAATTTGTGAATGAGTATGT GGGTGAGCTTATAGATGAAGAAGAATGCAGAGCTCGAATTCGCTATGCTCAAGAACATGA TATCACTAATTTCTATATGCTCACCCTAGACAAAGACCGAATCATTGATGCTGGTCCCAA AGGAAACTATGCTCGGTTCATGAATCATTGCTGCCAGCCCAACTGTGAAACACAGAAGTG GTCTGTGAATGGAGATACCCGTGTAGGCCTTTTTGCACTAAGTGACATTAAAGCAGGCAC TGAACTTACCTTCAACTACAACCTAGAATGTCTTGGGAATGGAAAGACTGTTTGCAAATG TGGAGCCCCGAACTGCAGTGGCTTCTTGGGTGTAAGGCCAAAGAATCAACCCATTGCCAC GGAAGAAAAGTCAAAGAAATTCAAGAAGAAGCAACAGGGAAAGCGCAGGACCCAGGGTGA AATCACAAAGGAGCGAGAAGATGAGTGTTTTAGTTGTGGGGATGCTGGCCAGCTCGTCTC CTGCAAGAAACCAGGCTGCCCAAAAGTTTACCACGCAGACTGTCTCAATCTGACCAAGCG ACCAGCAGGGAAATGGGAATGTCCGTGGCATCAGTGTGACATCTGCGGGAAGGAAGCAGC CTCCTTCTGTGAGATGTGCCCCAGCTCCTTTTGTAAGCAGCATCGAGAAGGGATGCTTTT CATTTCCAAACTGGATGGGCGTCTGTCTTGTACTGAGCATGACCCCTGTGGGCCCAATCC TCTGGAACCTGGGGAGATCCGTGAGTATGTGCCTCCCCCAGTACCGCTGCCTCCAGGGCC AAGCACTCACCTGGCAGAGCAATCAACAGGAATGGCTGCTCAGGCACCCAAAATGTCAGA TAAACCTCCTGCTGACACCAACCAGATGCTGTCGCTCTCCAAAAAAGCTCTGGCAGGGAC TTGTCAGAGGCCACTGCTACCTGAAAGACCTCTTGAGAGAACTGACTCCAGGCCCCAGCC TTTAGATAAGGTCAGAGACCTCGCTGGGTCAGGGACCAAATCCCAATCCTTGGTTTCCAG CCAGAGGCCACTGGACAGGCCACCAGCAGTGGCAGGACCAAGACCCCAGCTAAGCGACAA ACCCTCTCCAGTGACCAGCCCAAGCTCCTCACCCTCAGTCAGGTCCCAACCACTGGAAAG ACCTCTGGGGACGGCTGACCCAAGGCTGGATAAATCCATAGGTGCTGCCAGCCCAAGGCC CCAGTCACTGGAGAAAACCTCAGTTCCCACTGGCCTGAGACTTCCGCCGCCAGACAGACT GCTCATTACTAGCAGTCCCAAACCCCAGACTTCAGACAGGCCTACTGACAAACCCCATGC CTCTTTGTCCCAGAGACTCCCACCTCCTGAGAAAGTACTATCAGCTGTGGTCCAGACCCT TGTAGCTAAAGAAAAAGCACTGAGGCCTGTGGACCAGAATACTCAGTCAAAAAATAGAGC TGCTTTGGTGATGGATCTCATAGACCTAACTCCTCGCCAGAAGGAGCGGGCAGCTTCACC TCATCAGGTCACACCACAGGCTGATGAGAAGATGCCAGTGTTGGAGTCAAGTTCATGGCC TGCCAGCAAAGGTCTGGGGCATATGCCGAGAGCTGTTGAGAAAGGCTGTGTGTCAGATCC TCTTCAGACATCTGGGAAAGCAGCAGCCCCTTCAGAGGACCCCTGGCAAGCTGTTAAATC ACTCACCCAGGCCAGACTTCTTTCTCAGCCTCCTGCCAAGGCCTTTTTATATGAGCCAAC AACTCAGGCCTCAGGAAGAGCTTCTGCAGGGGCTGAGCAGACCCCAGGGCCTCTTAGCCA ATCCCCGGGCCTGGTGAAGCAGGCGAAGCAGATGGTCGGAGGCCAGCAACTACCTGCACT TGCCGCCAAGAGTGGGCAATCTTTTAGGTCTCTCGGGAAGGCCCCAGCCTCCCTCCCCAC TGAAGAAAAGAAGTTGGTAACCACAGAGCAAAGTCCCTGGGCCCTGGGAAAAGCCTCATC ACGGGCAGGGCTCTGGCCCATAGTGGCTGGACAGACACTGGCACAGTCTTGCTGGTCTGC TGGGAGCACACAGACATTGGCACAGACTTGCTGGTCTCTTGGAAGAGGGCAAGACCCCAA ACCAGAGCAAAATACACTTCCAGCTCTTAACCAGGCTCCTTCCAGTCACAAGTGTGCAGA ATCAGAACAGAAGTAGTACCAATCAATGTCACATGAACAAACAAGCTGCCCCCAGGGTAC CATTTGGGGAGGGGAAATCTTTTCTTTCTTTCCCCCTTAAAAAAAAACACATCTGCCCCG AACACTTTCCCACTGTTATTCTTTCCTCATATCCCAACACTCAGAACTCTTGTGACATTA GCCAGTGGGGGCTTATGGTTGTGTGAACCATGTATGAAAATCCAGTGGGCCCCAACCAAG GAGACAGACAGACTTGGGTCTCTTTCCCCCAACTTTTCCACATGGTCATCGTGAAATAAA AAGTCCACTCTGGAGTCAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_022455 |
| Insert Size | 8800 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a good match to the protein associated to this reference except for one SNP. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_022455.3, NP_071900.2 |
| RefSeq Size | 8458 bp |
| RefSeq ORF | 8091 bp |
| Locus ID | 64324 |
| UniProt ID | Q96L73 |
| Domains | PWWP, SET, PHD, AWS |
| Protein Families | Druggable Genome |
| Protein Pathways | Lysine degradation |
| Gene Summary | This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Sep 2018] Transcript Variant: This variant (2), also known as ARA267-beta, represents the longer transcript, and encodes the longer isoform b. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC221517 | NSD1 (Myc-DDK-tagged)-Human nuclear receptor binding SET domain protein 1 (NSD1), transcript variant 2 |
CNY 26,208.00 |
|
| RC221517L1 | Lenti ORF clone of Human nuclear receptor binding SET domain protein 1 (NSD1), transcript variant 2, Myc-DDK-tagged |
CNY 28,608.00 |
|
| RG221517 | NSD1 (tGFP-tagged) - Human nuclear receptor binding SET domain protein 1 (NSD1), transcript variant 2 |
CNY 33,820.00 |
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