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Metabotropic Glutamate Receptor 1 (GRM1) (NM_000838) Human Untagged Clone
CAT＃: SC309954
GRM1 (untagged)-Human glutamate receptor, metabotropic 1 (GRM1), transcript variant 1
CNY 12,480.00
货期*
现货
规格
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GPRC1A; GRM1A; mGlu1; MGLUR1; MGLUR1A; SCAR13 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_000838 edited
TTGTGTAATACGACTCCTATAGGGCGGCCGCGTGGCCACGGTCCTCTGGCCCCGGGACCA TAGCGCTGTCTACCCCGACTCAGGTACTCAGCATCTAGCTCACCGCTGCCAACACGACTT CCACTGTACTCTTGATCAATTTACCTTGATGCACTACCGGTGAAGAACGGGGACTCGAAT TCCCTTACAAACGCCTCCAGCTTGTAGAGGCGGTCGTGGAGGACCCAGAGGAGGAGACGA AGGGGAAGGAGGCGGTGGTGGAGGAGGCAAAGGCCTTGGACGACCATTGTTGGCGAGGGG CACCACTCCGGGAGAGGCGGCGCTGGGCGTCTTGGGGGTGCGCGCCGGGAGCCTGCAGCG GGACCAGCGTGGGAACGCGGCTGGCAGGCTGTGGACCTCGTCCTCACCACCATGGTCGGG CTCCTTTTGTTTTTTTTCCCAGCGATCTTTTTGGAGGTGTCCCTTCTCCCCAGAAGCCCC GGCAGGAAAGTGTTGCTGGCAGGAGCGTCGTCTCAGCGCTCGGTGGCCAGAATGGACGGA GATGTCATCATTGGAGCCCTCTTCTCAGTCCATCACCAGCCTCCGGCCGAGAAAGTGCCC GAGAGGAAGTGTGGGGAGATCAGGGAGCAGTATGGCATCCAGAGGGTGGAGGCCATGTTC CACACGTTGGATAAGATCAACGCGGACCCGGTCCTCCTGCCCAACATCACCCTGGGCAGT GAGATCCGGGACTCCTGCTGGCACTCTTCCGTGGCTCTGGAACAGAGCATTGAGTTCATT AGGGACTCTCTGATTTCCATTCGAGATGAGAAGGATGGGATCAACCGGTGTCTGCCTGAC GGCCAGTCCCTCCCCCCAGGCAGGACTAAGAAGCCCATTGCGGGAGTGATCGGTCCCGGC TCCAGCTCTGTAGCCATTCAAGTGCAGAACCTGCTCCAGCTCTTCGACATCCCCCAGATC GCTTATTCAGCCACAAGCATCGACCTGAGTGACAAAACTTTGTACAAATACTTCCTGAGG GTTGTCCCTTCTGACACTTTGCAGGCAAGGGCCATGCTTGACATAGTCAAACGTTACAAT TGGACCTATGTCTCTGCAGTCCACACGGAAGGGAATTATGGGGAGAGCGGAATGGACGCT TTCAAAGAGCTGGCTGCCCAGGAAGGCCTCTGTATCGCCCATTCTGACAAAATCTACAGC AACGCTGGGGAGAAGAGCTTTGACCGACTCTTGCGCAAACTCCGAGAGAGGCTTCCCAAG GCTAGAGTGGTGGTCTGCTTCTGTGAAGGCATGACAGTGCGAGGACTCCTGAGCGCCATG CGGCGCCTTGGCGTCGTGGGCGAGTTCTCACTCATTGGAAGTGATGGATGGGCAGACAGA GATGAAGTCATTGAAGGTTATGAGGTGGAAGCCAACGGGGGAATCACGATAAAGCTGCAG TCTCCAGAGGTCAGGTCATTTGATGATTATTTCCTGAAACTGAGGCTGGACACTAACACG AGGAATCCCTGGTTCCCTGAGTTCTGGCAACATCGGTTCCAGTGCCGCCTTCCAGGACAC CTTCTGGAAAATCCCAACTTTAAACGAATCTGCACAGGCAATGAAAGCTTAGAAGAAAAC TATGTCCAGGACAGTAAGATGGGGTTTGTCATCAATGCCATCTATGCCATGGCACATGGG CTGCAGAACATGCACCATGCCCTCTGCCCTGGCCACGTGGGCCTCTGCGATGCCATGAAG CCCATCGACGGCAGCAAGCTGCTGGACTTCCTCATCAAGTCCTCATTCATTGGAGTATCT GGAGAGGAGGTGTGGTTTGATGAGAAAGGAGACGCTCCTGGAAGGTATGATATCATGAAT CTGCAGTACACTGAAGCTAATCGCTATGACTATGTGCACGTTGGAACCTGGCATGAAGGA GTGCTGAACATTGATGATTACAAAATCCAGATGAACAAGAGTGGAGTGGTGCGGTCTGTG TGCAGTGAGCCTTGCTTAAAGGGCCAGATTAAGGTTATACGGAAAGGAGAAGTGAGCTGC TGCTGGATTTGCACGGCCTGCAAAGAGAATGAATATGTGCAAGATGAGTTCACCTGCAAA GCTTGTGACTTGGGATGGTGGCCCAATGCAGATCTAACAGGCTGTGAGCCCATTCCTGTG CGCTATCTTGAGTGGAGCAACATCGAATCCATTATAGCCATCGCCTTTTCATGCCTGGGA ATCCTTGTTACCTTGTTTGTCACCCTAATCTTTGTACTGTACCGGGACACACCAGTGGTC AAATCCTCCAGTCGGGAGCTCTGCTACATCATCCTAGCTGGCATCTTCCTTGGTTATGTG TGCCCATTCACTCTCATTGCCAAACCTACTACCACCTCCTGCTACCTCCAGCGCCTCTTG GTTGGCCTCTCCTCTGCGATGTGCTACTCTGCTTTAGTGACTAAAACCAATCGTATTGCA CGCATCCTGGCTGGCAGCAAGAAGAAGATCTGCACCCGGAAGCCCAGGTTCATGAGTGCC TGGGCTCAGGTGATCATTGCCTCAATTCTGATTAGTGTGCAACTAACCCTGGTGGTAACC CTGATCATCATGGAACCCCCTATGCCCATTCTGTCCTACCCAAGTATCAAGGAAGTCTAC CTTATCTGCAATACCAGCAACCTGGGTGTGGTGGCCCCTTTGGGCTACAATGGACTCCTC ATCATGAGCTGTACCTACTATGCCTTCAAGACCCGCAACGTGCCCGCCAACTTCAACGAG GCCAAATATATCGCGTTCACCATGTACACCACCTGTATCATCTGGCTAGCTTTTGTGCCC ATTTACTTTGGGAGCAACTACAAGATCATCACAACTTGCTTTGCAGTGAGTCTCAGTGTA ACAGTGGCTCTGGGGTGCATGTTCACTCCCAAGATGTACATCATTATTGCCAAGCCTGAG AGGAATGTCCGCAGTGCCTTCACCACCTCTGATGTTGTCCGCATGCATGTTGGCGATGGC AAGCTGCCCTGCCGCTCCAACACTTTCCTCAACATCTTCCGAAGAAAGAAGGCAGGGGCA GGGAATGCCAATTCTAATGGCAAGTCTGTGTCATGGTCTGAACCAGGTGGAGGACAGGTG CCCAAGGGACAGCATATGTGGCACCGCCTCTCTGTGCACGTGAAGACCAATGAGACGGCC TGCAACCAAACAGCCGTCATCAAGCCCCTCACTAAAAGTTACCAAGGCTCTGGCAAGAGC CTGACCTTTTCAGATACCAGCACCAAGACCCTTTACAACGTAGAGGAGGAGGAGGATGCC CAGCCGATTCGCTTTAGCCCGCCTGGTAGCCCTTCCATGGTGGTGCACAGGCGCGTGCCA AGCGCGGCGACCACTCCGCCTCTGCCGTCCCACCTGACCGCAGAGGAGACCCCCCTCTTC CTGGCCGAACCAGCCCTCCCCAAGGGCTTGCCCCCTCCTCTCCAGCAGCAGCAGCAACCC CCTCCACAGCAGAAATCGCTGATGGACCAGCTCCAGGGAGTGGTCAGCAACTTCAGTACC GCGATCCCGGATTTTCACGCGGTGCTGGCAGGCCCCGGGGGTCCCGGGAACGGGCTGCGG TCCCTGTACCCGCCCCCGCCACCTCCGCAGCACCTGCAGATGCTGCCGCTGCAGCTGAGC ACCTTTGGGGAGGAGCTGGTCTCCCCGCCCGCGGACGACGACGACGACAGCGAGAGGTTT AAGCTCCTCCAGGAGTACGTGTATGAGCACGAGCGGGAAGGGAACACGGAAGAAGACGAA CTGGAAGAGGAGGAGGAGGACCTGCAGGCGGCCAGCAAACTGACCCCGGATGATTCGCCT GCGCTGACGCCTCCGTCGCCTTTCCGCGACTCGGTGGCCTCGGGCAGCTCGGTGCCCAGC TCCCCCGTGTCCGAGTCGGTGCTCTGCACCCCTCCCAACGTATCCTACGCCTCTGTCATT CTGCGGGACTACAAGCAAAGCTCTTCCACCCTGTAAGGGGGAAGGGTCCACATAGAAAAG CAAGACAAGCCAGAGATCTCCCACACCTCCAGAGATGTGCAAACAGCTGGGAGGAAAAGC CTGGGAGTGGGGGGCCTCGTCGGGAGGACAGGAGACCGCTGCTGCTGCTGCCGCTACTGC TGCTGCTGCCTTAAGTAGGAAGAGAGGGAAGGACACCAAGCAAAAAATGTTCAGGCCAGG ATTCGGATTCTTGAATTACTCGAAGCCTTCTCTGGGAAGAAAGGGAATTCTGACAAAGCA CAATTCCATATGGTATGTAACTTTTATCACAAATCAAATAGTGACATCACAAACATAATG TCCTCTTTTGCACAATTGTGCATAGATATATATATGCCCACACACACTGGGCCATGCTTG GCAAGGAACAGACCACGTGGCATCCAGTCGGATCATGAGTTCACCTGATGCATTCGGAGT GAGCTGGTGGAGCCAGACAGAGCAGGTGCGGGGAAGGGAAGGGCCAGGCCAGACCCATCC CAAACGGATGATGGGATGATGGGACAGCAGTTCCTTGCTCAGAAGCCCTTCTCCCCGCTG GGCTGACAGACTCCTCATCTTCAGGAGACTCAGGAATGGAGCGGTACAGGGGTCTCTCTT CATCCACCGCAACCCATCCAGTGCCAGCTTTGAGATTGCACTTGAAGAAAGGTGCATGGA CCCCCTGCTGCTCTGCAGATTCCCTTTATTTAGGAAAACAGGAATAAGAGCAAAATTATC ACCAAAAAGTGCTTCATCAGGCGTGCTACAGGAGGAAGGAGCTAGAAATAGAACAATCCA TCAGCATGAGACTTTGAAAAAAAAAACACATGATCAGCTTCTCATGTTCCATATTCACTT ATTGGCGATTTGGGGAAAAGGCCGGAACAAGAGATTGTTACGAGAGTGGCAGAAACCCTT TTGTAGATTGACTTGTGTTTGTGCCAAGCGGGCTTTCCATTGACCTTCAGTTAAAGAACA AACCATGTGACAAAATTGTTACCTTCCACTTACTGTAGCAAATAATACCTACAAGTTGAA CTTCTAAGATGCGTATATGTACAATTTGGTGCCATTATTTCTCCTACGTATTAGAGAAAC AAATCCATCTTTGAATCTAATGGTGTACTCATAGCAACTATTACTGGTTTAAATGACAAA TAATTCTATCCTATTGTCACTGAAGTCCTTGTAACTAGCGAGTGAATGTGTTCCTGTGTC CTTGTATATGTGCGATCGTAAAATTTGTGCAATGTAATGTCAAATTGACCTGTCAATGTC AACCTAGTAGTCAATCTAACTGCAATTAGAAATTGTCTTTTGAATATACTATATATATTT TTTATGTTCCAATAATGTTTTATACATCATTGTCATCAATATCTACAGAAGCTCTTTGAC GGTTTGAATACTATGGCTCAAGGTTTTCATATGCAGCTCGGATGGACATTTTTCTTCTAA GATGGAACTTATTTTTCAGATATTTTCTGATGTGGAGATATGTTATTAATGAAGTGGTTT GAAAATTTGTTATATTAAAAGTGCACAAAAACTGAGAGTGAAAATAAAAGGTACATTTTA TAAGCTTGCACACATTATTAACACATAAGATTGAACAAAGCATTTAGATTATTCCAGGTT ATATCATTTTTTTAAAGATTTTCCACAGCTACTTGAGTGTCTAACATACAGTAACATCTA ACTCAGCTAATAATTTGTAAAATCTTTATCAATCACATTGTGGCCTCTTTTAATTTTTAT GTTCATGGACTTTTATTCCTGTGTCTTGGCTGTCATAACTTTTTATTTCTGCTATTTGCT GTTGTGTAATATCCATGGACATGTAATCCACTTACTCCATCTTTACAATCCCTTTTTACC ACCAATAAAAGGATTTTTTCTTGCTGTTTTGATTTCTTCTATTATTTGTGGAATGAATTA TACCCCCCTTAAATATCTTTGTTTATGCCTTATGTTCAGTCATATTTTAATATGCTTCCT TCATATTGAAGCTGCTGATTTCTCAGCCAAAAATCATCTTAGAATCTTTAAATATCCATT GCATCATTTGTTCAGAATTTAACATCCATTCCAATGTTGGAGGCTTGTATTACTTATATT TCATCATATTCTATTGCCAAGTTTAGTCAGTTCCACACCAAGAATGAACTGCATTTCCTT TAAAAATTATTTTAAAACACCTTTATTGAAAAGATCTCATGACTGAGATGTGGACTTTGG TTCCATGTTTTCATTGTAAGAAAGCAGAGAGCGGAAAATCAATGGCTCCAGTGATTAATA GATGGGTTTTTAGTAATTGACAAATTCATGAGGGAAAGCATATGATCTCTTTATTAGTGA ATCATGCTTATTTTTTACTCTTAATGCCACTAATATACATCCCTAATATCACAGGGCTTG TGCATTCAGATTTTTAAAAAATTAGGATAGATAAGGAAACAACTTATATTCAAGTGTAAG ATGATATCAGGTTGGTCTAAGACTTTTGGTGAACACGTTCATTCAACTGTGATCACTTTA TTACTCTGAATGCCTACTATTATCCTGATTATGGGGTCTCCTGAATAAATAGAGTATTAG TCCTTATGTCATCATTGTTCAAAATTGGAGATGTACACATACATACCCTATACCAAGAGG GCCGAAACTCTTCACCCTGATGTATGTTCTGATACAAGTTGTTCAGCTTCTTGTAAATGT GTTTTCCTTCGGCTTGTTACTGCCTTTTGTCAAATAATCTTGACAATGCTGTATAATAAA TATTTTCTATTTATTAAAAAAAAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_000838 unedited
TACGATTGTGTAATACGACTCCTATAGGGCGGCCGCGTGGCCACGGTCCTCTGGCCCCGG GACCATAGCGCTGTCTACCCCGACTCAGGTACTCAGCATCTAGCTCACCGCTGCCAACAC GACTTCCACTGTACTCTTGATCAATTTACCTTGATGCACTACCGGTGAAGAACGGGGACT CGAATTCCCTTACAAACGCCTCCAGCTTGTAGAGGCGGTCGTGGAGGACCCAGAGGAGGA GACGAAGGGGAAGGAGGCGGTGGTGGAGGAGGCAAAGGCCTTGGACGACCATTGTTGGCG AGGGGCACCACTCCGGGAGAGGCGGCGCTGGGCGTCTTGGGGGTGCGCGCCGGGAGCCTG CAGCGGGACCAGCGTGGGAACGCGGCTGGCAGGCTGTGGACCTCGTCCTCACCACCATGG TCGGGCTCCTTTTGTTTTTTTTCCCAGCGATCTTTTTGGAGGTGTCCCTTCTCCCCAGAA GCCCCGGCAGGAAAGTGTTGCTGGCAGGAGCGTCGTCTCAGCGCTCGGTGGCCAGAATGG ACGGAGATGTCATCATTGGAGCCCTCTTCTCAGTCCATCACCAGCCTCCGGCCGAGAAAG TGCCCGAGAGGAAGTGTGGGGAGATCAGGGAGCAGTATGGCATCCAGAGGGTGGAGGCCA TGTTCCACACGTTGGATAAGATCAACGCGGACCCGGTCCTCCTGCCCAACATCACCCTGG GCAGTGAGATCCGGGACTCCTGCTGGCACTCTTCCGTGGCTCTGGAACAGAGCATTGAGT TCATTAGGGACTCTCTGATTTCCATTCGAGATGAGAAGGATGGGATCAACCGGTGTCTGC CTGACGGCCAGTCCCTCCCCCAGGCAGACTAGAGCCAATTGCGGGAGTGATCGGTCCCGG CTTCAGCTCTGTAGCCATTCAGTTGCAGAACCTGCTCCAGCTCTTCGACATC >OriGene 3' genomic read for NM_000838 unedited
CAATAGGAGGTGACAACCTTCAGGGCCGGAGAGGCACTGGGGAGGGGTCACAGGGATGCC ACCCGGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTT TTTTTTTTTTTTTTTTTTTAATAAATAGAAAATATTTATTATACAGCATTGTCAAGATTA TTTGACAAAAGGCAGTAACAAGCCGAAGGAAAACACATTTACAAGAAGCTGAACAACTTG TATCAAAACATACATCAGGGGGAAGAGTTTCGGCCCTCTTGGTATAGGGTATGTATGTGT ACATCTCCAATTTTGAACAATGATGACATAAGGACTAATACTCTATTTATTCAGGAGACC CCATAATCAGGATAATAGTAGGCATTCAGAGTAATAAAGTGATCACAGTTGAATGAACGT GTTCACCAAAAGTCTTAGACCAACCTGATATCATCTTACACTTGAATATAAGTTGTTTCC TTATCTATCCTAATTTTTTAAAAATCTGAATGCACAAGCCCTGTGATATTAGGGATGTAT ATTAGTGGCATTAAAAGTAAAAAATAAGCATGATTCACTAATAAAAGAGATCATATGCTT TCCCTCATGAATTTGTCAATTACTAAAAACCCATCTATTAATCACTGGAGCCATTGATTT TCCGCTCTCTGCTTTTCTTACAATGAAAACATGGAACCAAAGTCCACCATCTCAGTCATG AGATCTTTTCAATAAAGGGTGTTTTAAAAAATTTTTAAAGGGAAATGCAGTTCATTCTTG GTGGTGGACTGACTAACCTGGCAATAGAATATGATGAAATATAGTAATACAGGCCCCAAC ACTGCAATGGATGGCAATTCTGAACAATGATGCACTGGAACTTAAAGGATCTCAGAAGAC TTTGGCGGAGAATCCCACCTCCACTCGGAGGGAGCCTATTAACATCGCGCGGAACGACG |
| Restriction Sites | Please inquire |
| ACCN | NM_000838 |
| Insert Size | 6800 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to differ from the protein associated to this reference by a single amino acid. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000838.2, NP_000829.1 |
| RefSeq Size | 6619 bp |
| RefSeq ORF | 3585 bp |
| Locus ID | 2911 |
| Domains | 7tm_3, ANF_receptor |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Calcium signaling pathway, Gap junction, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction |
| Gene Summary | This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013] Transcript Variant: This variant (1) encodes the longer isoform (alpha). |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC214400 | GRM1 (Myc-DDK-tagged)-Human glutamate receptor, metabotropic 1 (GRM1), transcript variant 1 |
CNY 12,472.00 |
|
| RC214400L1 | Lenti-ORF clone of GRM1 (Myc-DDK-tagged)-Human glutamate receptor, metabotropic 1 (GRM1), transcript variant 1 |
CNY 14,872.00 |
|
| RC214400L2 | Lenti-ORF clone of GRM1 (mGFP-tagged)-Human glutamate receptor, metabotropic 1 (GRM1), transcript variant 1 |
CNY 15,510.00 |
|
| RC214400L3 | Lenti-ORF clone of GRM1 (Myc-DDK-tagged)-Human glutamate receptor, metabotropic 1 (GRM1), transcript variant 1 |
CNY 14,872.00 |
|
| RC214400L4 | Lenti-ORF clone of GRM1 (mGFP-tagged)-Human glutamate receptor, metabotropic 1 (GRM1), transcript variant 1 |
CNY 15,510.00 |
|
| RG214400 | GRM1 (tGFP-tagged) - Human glutamate receptor, metabotropic 1 (GRM1), transcript variant 1 |
CNY 14,072.00 |
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