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AASS (NM_005763) Human Untagged Clone
CAT＃: SC314936
AASS (untagged)-Human aminoadipate-semialdehyde synthase (AASS), nuclear gene encoding mitochondrial protein
CNY 17,860.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | LKR/SDH; LKRSDH; LORSDH |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC314936 representing NM_005763.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGCTGCAAGTACATAGGACTGGACTGGGCAGGCTGGGGGTCAGCCTCTCCAAGGGTCTTCACCACAAA GCTGTGTTGGCCGTCCGGAGGGAGGATGTGAACGCCTGGGAGAGAAGGGCCCCGCTAGCTCCCAAGCAC ATCAAAGGCATCACCAATCTGGGATACAAGGTCTTGATACAGCCTTCGAATCGGCGGGCCATTCATGAT AAGGACTATGTCAAAGCTGGTGGCATTCTTCAGGAGGATATTTCTGAAGCTTGTCTAATTTTAGGAGTT AAAAGACCTCCAGAGGAAAAATTAATGTCCAGGAAGACTTATGCATTTTTCTCCCACACAATAAAAGCT CAGGAGGCCAATATGGGCTTGTTGGATGAGATTCTAAAACAGGAAATTCGCCTTATTGATTATGAGAAA ATGGTGGATCATAGAGGAGTACGGGTAGTGGCATTTGGACAGTGGGCTGGTGTGGCAGGAATGATCAAC ATTTTACATGGAATGGGTTTAAGGCTCCTTGCTTTGGGACATCACACACCTTTTATGCACATTGGCATG GCTCATAACTACAGGAATAGCAGTCAGGCTGTGCAAGCTGTCCGTGATGCTGGCTATGAAATATCTTTG GGTTTGATGCCTAAGTCAATAGGACCCTTAACATTTGTGTTCACAGGAACTGGTAATGTTTCTAAGGGA GCCCAAGCAATCTTTAATGAGCTACCTTGTGAATATGTGGAGCCCCATGAATTAAAAGAAGTTTCCCAA ACTGGAGACCTCAGAAAAGTGTATGGGACGGTGTTAAGTCGTCATCATCATCTTGTCAGGAAAACAGAT GCTGTGTATGATCCTGCAGAGTATGACAAACATCCGGAGCGCTACATAAGTCGTTTTAATACTGATATT GCACCCTATACAACTTGCTTAATTAATGGAATCTACTGGGAACAAAACACTCCTCGCCTCCTAACCCGC CAAGATGCTCAGAGTCTCCTGGCTCCGGGCAAGTTCTCACCTGCTGGTGTGGAAGGCTGCCCTGCATTA CCACACAAACTCGTGGCAATATGTGACATTTCAGCTGACACAGGAGGGTCTATAGAGTTTATGACTGAG TGTACAACAATAGAGCATCCCTTTTGCATGTATGATGCAGACCAGCATATTATTCATGACAGTGTTGAA GGCTCGGGGATCCTGATGTGTTCCATTGACAATTTGCCGGCACAGCTCCCAATTGAAGCTACAGAATGC TTTGGAGACATGCTTTACCCTTATGTTGAAGAAATGATATTATCAGACGCGACACAGCCTCTTGAAAGT CAGAATTTTTCTCCTGTGGTGAGAGATGCAGTGATTACATCCAACGGTACATTACCTGATAAATATAAA TATATCCAGACACTCCGGGAGAGCAGGGAACGTGCTCAGTCACTTTCAATGGGCACCAGGAGAAAGGTT TTGGTTCTTGGATCTGGCTACATATCTGAGCCTGTATTAGAATATTTATCAAGAGATGGCAATATAGAA ATAACAGTAGGATCTGACATGAAGAATCAAATTGAACAGTTAGGCAAGAAATATAATATTAATCCTGTT AGCATGGACATTTGTAAACAAGAAGAGAAGCTGGGCTTCTTGGTGGCAAAACAGGATCTTGTCATCAGC TTGTTGCCTTATGTATTGCACCCTCTTGTGGCCAAGGCCTGCATCACAAACAAAGTTAACATGGTCACT GCAAGCTACATCACACCAGCACTAAAAGAATTGGAAAAGAGTGTGGAAGATGCTGGCATCACAATCATT GGTGAATTGGGATTGGACCCTGGTCTGGATCACATGTTAGCAATGGAAACAATAGATAAAGCCAAGGAA GTGGGAGCCACGATTGAATCATATATTTCCTACTGTGGTGGGCTTCCAGCCCCTGAACATTCAAACAAT CCATTGAGATATAAATTTAGCTGGAGTCCAGTGGGAGTTTTGATGAATGTAATGCAGTCTGCCACCTAT CTGCTCGATGGAAAGGTTGTGAATGTTGCAGGAGGCATCTCCTTTCTTGATGCCGTTACGTCCATGGAT TTTTTTCCAGGATTAAATTTGGAAGGCTATCCTAACAGAGACAGTACGAAATATGCTGAGATTTATGGC ATTTCTTCTGCTCACACTTTGTTGCGGGGGACACTGAGATATAAGGGATATATGAAAGCTTTGAATGGA TTTGTAAAATTAGGTCTTATAAACAGAGAAGCGCTTCCTGCCTTTAGACCTGAGGCCAACCCTCTCACC TGGAAACAACTCCTCTGTGACCTAGTTGGGATTTCACCCTCCTCTGAGCATGATGTGTTGAAGGAAGCT GTTCTTAAGAAACTAGGAGGAGACAATACCCAGTTGGAGGCTGCTGAATGGTTGGGCTTACTTGGGGAT GAACAAGTTCCTCAGGCAGAGTCCATTCTGGATGCCCTCTCCAAGCATTTGGTCATGAAGCTTTCCTAT GGTCCTGAAGAAAAAGATATGATTGTGATGAGAGACAGCTTTGGAATCAGACATCCTTCTGGACATTTA GAACATAAAACGATTGATCTTGTGGCTTATGGGGACATCAATGGCTTTTCAGCCATGGCTAAAACCGTG GGGTTACCCACCGCCATGGCAGCCAAAATGTTGCTTGATGGTGAAATTGGAGCCAAAGGCCTAATGGGG CCCTTTTCAAAGGAGATCTATGGACCAATATTGGAGCGAATTAAAGCAGAAGGCATTATATATACTACA CAGAGTACAATTAAACCATAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_005763 |
| Insert Size | 2781 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_005763.3 |
| RefSeq Size | 5887 bp |
| RefSeq ORF | 2781 bp |
| Locus ID | 10157 |
| UniProt ID | Q9UDR5 |
| Domains | Saccharop_dh, AlaDh_PNT_C, AlaDh_PNT_N |
| Protein Families | Druggable Genome |
| Protein Pathways | Lysine biosynthesis, Lysine degradation, Metabolic pathways |
| MW | 102.1 kDa |
| Gene Summary | This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia. [provided by RefSeq, Jul 2008] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC224831 | AASS (Myc-DDK-tagged)-Human aminoadipate-semialdehyde synthase (AASS), nuclear gene encoding mitochondrial protein |
CNY 10,168.00 |
|
| RC224831L3 | Lenti ORF clone of Human aminoadipate-semialdehyde synthase (AASS), nuclear gene encoding mitochondrial protein, Myc-DDK-tagged |
CNY 11,690.00 |
|
| RC224831L4 | Lenti ORF clone of Human aminoadipate-semialdehyde synthase (AASS), nuclear gene encoding mitochondrial protein, mGFP tagged |
CNY 11,690.00 |
|
| RG224831 | AASS (tGFP-tagged) - Human aminoadipate-semialdehyde synthase (AASS), nuclear gene encoding mitochondrial protein |
CNY 10,740.00 |
