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Laminin 2 alpha (LAMA2) (NM_001079823) Human Untagged Clone
CAT＃: SC315910
LAMA2 (untagged)-Human laminin, alpha 2 (LAMA2), transcript variant 2
CNY 59,950.00
货期*
12周
规格
Product images
经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | LAMM; MDC1A |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_001079823, the custom clone sequence may differ by one or more nucleotides
ATGCCGGGAGCCGCCGGGGTCCTCCTCCTTCTGCTGCTCTCCGGAGGCCTCGGGGGCGTA CAGGCGCAGCGGCCGCAGCAGCAGCGGCAGTCACAGGCACATCAGCAAAGAGGTTTATTC CCTGCTGTCCTGAATCTTGCTTCTAATGCTCTTATCACGACCAATGCAACATGTGGAGAA AAAGGACCTGAAATGTACTGCAAATTGGTAGAACATGTCCCTGGGCAGCCTGTGAGGAAC CCGCAGTGTCGAATCTGCAATCAAAACAGCAGCAATCCAAACCAGAGACACCCGATTACA AATGCTATTGATGGAAAGAACACTTGGTGGCAGAGTCCCAGTATTAAGAATGGAATCGAA TACCATTATGTGACAATTACCCTGGATTTACAGCAGGTGTTCCAGATCGCGTATGTGATT GTGAAGGCAGCTAACTCCCCCCGGCCTGGAAACTGGATTTTGGAACGCTCTCTTGATGAT GTTGAATACAAGCCCTGGCAGTATCATGCTGTGACAGACACGGAGTGCCTAACGCTTTAC AATATTTATCCCCGCACTGGGCCACCGTCATATGCCAAAGATGATGAGGTCATCTGCACT TCATTTTACTCCAAGATACACCCCTTAGAAAATGGAGAGATTCACATCTCTTTAATCAAT GGGAGACCAAGTGCCGATGATCCTTCTCCAGAACTGCTAGAATTTACCTCCGCTCGCTAT ATTCGCCTGAGATTTCAGAGGATCCGCACACTGAATGCTGACTTGATGATGTTTGCTCAC AAAGACCCAAGAGAAATTGACCCCATTGTCACCAGAAGATATTACTACTCGGTCAAGGAT ATTTCAGTTGGAGGGATGTGCATCTGCTATGGTCATGCCAGGGCTTGTCCACTTGATCCA GCGACAAATAAATCTCGCTGTGAGTGTGAGCATAACACATGTGGCGATAGCTGTGATCAG TGCTGTCCAGGATTCCATCAGAAACCCTGGAGAGCTGGAACTTTTCTAACTAAAACTGAA TGTGAAGCATGCAATTGTCATGGAAAAGCTGAAGAATGCTATTATGATGAAAATGTTGCC AGAAGAAATCTGAGTTTGAATATACGTGGAAAGTACATTGGAGGGGGTGTCTGCATTAAT TGTACCCAAAACACTGCTGGTATAAACTGCGAGACATGTACTGATGGCTTCTTCAGACCC AAAGGGGTATCTCCAAATTATCCAAGGCCATGCCAGCCATGTCATTGCGATCCAATTGGT TCCTTAAATGAAGTCTGTGTCAAGGATGAGAAACATGCTCGACGAGGTTTGGCACCTGGA TCCTGTCATTGCAAAACTGGTTTTGGAGGTGTGAGCTGTGATCGGTGTGCCAGGGGCTAC ACTGGCTACCCGGACTGCAAAGCCTGTAACTGCAGTGGGTTAGGGAGCAAAAATGAGGAT CCTTGTTTTGGCCCCTGTATCTGCAAGGAAAATGTTGAAGGAGGAGACTGTAGTCGTTGC AAATCCGGCTTCTTCAATTTGCAAGAGGATAATTGGAAAGGCTGCGATGAGTGTTTCTGT TCAGGGGTTTCAAACAGATGTCAGAGTTCCTACTGGACCTATGGCAAAATACAAGATATG AGTGGCTGGTATCTGACTGACCTTCCTGGCCGCATTCGAGTGGCTCCCCAGCAGGACGAC TTGGACTCACCTCAGCAGATCAGCATCAGTAACGCGGAGGCCCGGCAAGCCCTGCCGCAC AGCTACTACTGGAGCGCGCCGGCTCCCTATCTGGGAAACAAACTCCCAGCAGTAGGAGGA CAGTTGACATTTACCATATCATATGACCTTGAAGAAGAGGAAGAAGATACAGAACGTGTT CTCCAGCTTATGATTATCTTAGAGGGTAATGACTTGAGCATCAGCACAGCCCAAGATGAG GTGTACCTGCACCCATCTGAAGAACATACTAATGTATTGTTACTTAAAGAAGAATCATTT ACCATACATGGCACACATTTTCCAGTCCGTAGAAAGGAATTTATGACAGTGCTTGCGAAT TTGAAGAGAGTCCTCCTACAAATCACATACAGCTTTGGGATGGATGCCATCTTCAGGTTG AGCTCTGTTAACCTTGAATCCGCTGTCTCCTATCCTACTGATGGAAGCATTGCAGCAGCT GTAGAAGTGTGTCAGTGCCCACCAGGGTATACTGGCTCCTCTTGTGAATCTTGTTGGCCT AGGCACAGGCGAGTTAACGGCACTATTTTTGGTGGCATCTGTGAGCCATGTCAGTGCTTT GGTCATGCGGAGTCCTGTGATGACGTCACTGGAGAATGCCTGAACTGTAAGGATCACACA GGTGGCCCATATTGTGATAAATGTCTTCCTGGTTTCTATGGCGAGCCTACTAAAGGAACC TCTGAAGACTGTCAACCCTGTGCCTGTCCACTCAATATCCCATCCAATAACTTTAGCCCA ACGTGCCATTTAGACCGGAGTCTTGGATTGATCTGTGATGGATGCCCTGTCGGGTACACA GGACCACGCTGTGAGAGGTGTGCAGAAGGCTATTTTGGACAACCCTCTGTACCTGGAGGA TCATGTCAGCCATGCCAATGCAATGACAACCTTGACTTCTCCATCCCTGGCAGCTGTGAC AGCTTGTCTGGCTCCTGTCTGATATGTAAACCAGGTACAACAGGCCGGTACTGTGAGCTC TGTGCTGATGGATATTTTGGAGATGCAGTTGATGCGAAGAACTGTCAGCCCTGTCGCTGT AATGCCGGTGGCTCTTTCTCTGAGGTTTGCCACAGTCAAACTGGACAGTGTGAGTGCAGA GCCAACGTTCAGGGTCAGAGATGTGACAAATGCAAGGCTGGGACCTTTGGCCTACAATCA GCAAGGGGCTGTGTTCCCTGCAACTGCAATTCTTTTGGGTCTAAGTCATTCGACTGTGAA GAGAGTGGACAATGTTGGTGCCAACCTGGAGTCACAGGGAAGAAATGTGACCGCTGTGCC CACGGCTATTTCAACTTCCAAGAAGGAGGCTGCACAGCTTGTGAATGTTCTCATCTGGGT AATAATTGTGACCCAAAGACTGGGCGATGCATTTGCCCTCCCAATACCATTGGAGAGAAA TGTTCTAAATGTGCACCCAATACCTGGGGCCACAGCATTACCACTGGTTGTAAGGCTTGT AACTGCAGCACAGTGGGATCCTTGGATTTCCAATGCAATGTAAATACAGGCCAATGCAAC TGTCATCCAAAATTCTCTGGTGCAAAATGTACAGAGTGCAGTCGAGGTCACTGGAACTAC CCTCGCTGCAATCTCTGTGACTGCTTCCTCCCTGGGACAGATGCCACAACCTGTGATTCA GAGACTAAAAAATGCTCCTGTAGTGATCAAACTGGGCAGTGCACTTGTAAGGTGAATGTG GAAGGCATCCACTGTGACAGATGCCGGCCTGGCAAATTCGGACTCGATGCCAAGAATCCA CTTGGCTGCAGCAGCTGCTATTGCTTCGGCACTACTACCCAGTGCTCTGAAGCAAAAGGA CTGATCCGGACGTGGGTGACTCTGAAGGCTGAGCAGACCATTCTACCCCTGGTAGATGAG GCTCTGCAGCACACGACCACCAAGGGCATTGTTTTTCAACATCCAGAGATTGTTGCCCAC ATGGACCTGATGAGAGAAGATCTCCATTTGGAACCTTTTTATTGGAAACTTCCAGAACAA TTTGAAGGAAAGAAGTTGATGGCCTATGGGGGCAAACTCAAGTATGCAATCTATTTCGAG GCTCGGGAAGAAACAGGTTTCTCTACATATAATCCTCAAGTGATCATTCGAGGTGGGACA CCTACTCATGCTAGAATTATCGTCAGGCATATGGCTGCTCCTCTGATTGGCCAATTGACA AGGCATGAAATTGAAATGACAGAGAAAGAATGGAAATATTATGGGGATGATCCTCGAGTC CATAGAACTGTGACCCGAGAAGACTTCTTGGATATACTATATGATATTCATTACATTCTT ATCAAAGCTACTTATGGAAATTTCATGCGACAAAGCAGGATTTCTGAAATCTCAATGGAG GTAGCTGAACAAGGACGTGGAACAACAATGACTCCTCCAGCTGACTTGATTGAAAAATGT GATTGTCCCCTGGGCTATTCTGGCCTGTCCTGTGAGGCATGCTTGCCGGGATTTTATCGA CTGCGTTCTCAACCAGGTGGCCGCACCCCTGGACCAACCCTGGGCACCTGTGTTCCATGT CAATGTAATGGACACAGCAGCCTGTGTGACCCTGAAACATCGATATGCCAGAATTGTCAA CATCACACTGCTGGTGACTTCTGTGAACGATGTGCTCTTGGATACTATGGAATTGTCAAG GGATTGCCAAATGACTGTCAGCAATGTGCCTGCCCTCTGATTTCTTCCAGTAACAATTTC AGCCCCTCTTGTGTCGCAGAAGGACTTGACGACTACCGCTGCACGGCTTGTCCACGGGGA TATGAAGGCCAGTACTGTGAAAGGTGTGCCCCTGGCTATACTGGCAGTCCAGGCAACCCT GGAGGCTCCTGCCAAGAATGTGAGTGTGATCCCTATGGCTCACTGCCTGTGCCCTGTGAC CCTGTCACAGGATTCTGCACGTGCCGACCTGGAGCCACGGGAAGGAAGTGTGACGGCTGC AAGCACTGGCATGCACGCGAGGGCTGGGAGTGTGTTTTTTGTGGAGATGAGTGCACTGGC CTTCTTCTCGGTGACTTGGCTCGCCTGGAGCAGATGGTCATGAGCATCAACCTCACTGGT CCGCTGCCTGCGCCATATAAAATGCTGTATGGTCTTGAAAATATGACTCAGGAGCTAAAG CACTTGCTGTCACCTCAGCGGGCCCCAGAGAGGCTTATTCAGCTGGCAGAGGGCAATCTG AATACACTCGTGACCGAAATGAACGAGCTGCTGACCAGGGCTACCAAAGTGACAGCAGAT GGCGAGCAGACCGGACAGGATGCTGAGAGGACCAACACAAGAGCAAAGTCCCTGGGAGAA TTCATTAAGGAGCTTGCCCGGGATGCAGAAGCTGTAAATGAAAAAGCTATAAAACTAAAT GAAACTCTAGGAACTCGAGACGAGGCCTTTGAGAGAAATTTGGAAGGGCTTCAGAAAGAG ATTGACCAGATGATTAAAGAACTGAGGAGGAAAAATCTAGAGACACAAAAGGAAATTGCT GAAGATGAGTTGGTAGCTGCAGAAGCCCTTCTGAAAAAAGTGAAGAAGCTGTTTGGAGAG TCCCGGGGGGAAAATGAAGAAATGGAGAAGGATCTCCGGGAAAAACTGGCTGACTACAAA AACAAAGTTGATGATGCTTGGGACCTTTTGAGAGAAGCCACAGATAAAATCAGAGAAGCT AATCGCCTATTTGCAGTAAATCAGAAAAACATGACTGCATTGGAGAAAAAGAAGGAGGCT GTTGAAAGCGGCAAACGACAAATTGAGAACACTTTAAAAGAGGGCAATGACATACTCGAT GAAGCCAACCGTCTTGCAGATGAAATCAACTCCATCATAGACTATGTTGAAGACATCCAA ACTAAATTGCCACCTATGTCTGAGGAGCTTAATGATAAAATAGATGACCTCTCCCAAGAA ATAAAGGACAGGAAGCTTGCTGAGAAGGTGTCCCAGGCTGAGAGCCACGCAGCTCAGTTG AATGACTCATCTGCTGTCCTTGATGGAATCCTTGATGAGGCTAAAAACATCTCCTTCAAT GCCACTGCAGCCTTCAAAGCTTACAGCAATATTAAGGACTATATTGATGAAGCTGAGAAA GTTGCCAAAGAAGCCAAAGATCTTGCACATGAAGCTACAAAACTGGCAACAGGTCCTCGG GGTTTATTAAAGGAAGATGCCAAAGGCTGTCTTCAGAAAAGCTTCAGGATTCTTAACGAA GCCAAGAAGTTAGCAAATGATGTAAAAGAAAATGAAGACCATCTAAATGGCTTAAAAACC AGGATAGAAAATGCTGATGCTAGAAATGGGGATCTCTTGAGAACTTTGAATGACACTTTG GGAAAGTTATCAGCTATTCCAAATGATACAGCTGCTAAACTGCAAGCTGTTAAGGACAAA GCCAGACAAGCCAACGACACAGCTAAAGATGTACTGGCACAGATTACAGAGCTCCACCAG AACCTCGATGGCCTGAAGAAGAATTACAATAAACTAGCAGACAGCGTCGCCAAAACGAAT GCTGTGGTTAAAGATCCTTCCAAGAACAAAATCATTGCCGATGCAGATGCCACTGTCAAA AATTTAGAACAGGAAGCTGACCGGCTAATAGATAAACTCAAACCCATCAAGGAACTTGAG GATAACCTAAAGAAAAACATCTCTGAGATAAAGGAATTGATAAACCAAGCTCGGAAACAA GCCAATTCTATCAAAGTATCTGTGTCTTCAGGAGGTGACTGCATTCGAACATACAAACCA GAAATCAAGAAAGGAAGTTACAATAATATTGTTGTCAACGTAAAGACAGCTGTTGCTGAT AACCTCCTCTTTTATCTTGGAAGTGCCAAATTTATTGACTTTCTGGCTATAGAAATGCGT AAAGGCAAAGTCAGCTTCCTCTGGGATGTTGGATCTGGAGTTGGACGTGTAGAGTACCCA GATTTGACTATTGATGACTCATATTGGTACCGTATCGTAGCATCAAGAACTGGGAGAAAT GGAACTATTTCTGTGAGAGCCCTGGATGGACCCAAAGCCAGCATTGTGCCCAGCACACAC CATTCGACGTCTCCTCCAGGGTACACGATTCTAGATGTGGATGCAAATGCAATGCTGTTT GTTGGTGGCCTGACTGGGAAATTAAAGAAGGCTGATGCTGTACGTGTGATTACATTCACT GGCTGCATGGGAGAAACATACTTTGACAACAAACCTATAGGTTTGTGGAATTTCCGAGAA AAAGAAGGTGACTGCAAAGGATGCACTGTCAGTCCTCAGGTGGAAGATAGTGAGGGGACT ATTCAATTTGATGGAGAAGGTTATGCATTGGTCAGCCGTCCCATTCGCTGGTACCCCAAC ATCTCCACTGTCATGTTCAAGTTCAGAACATTTTCTTCGAGTGCTCTTCTGATGTATCTT GCCACACGAGACCTGAGAGATTTCATGAGTGTGGAGCTCACTGATGGGCACATAAAAGTC AGTTACGATCTGGGCTCAGGAATGGCTTCCGTTGTCAGCAATCAAAACCATAATGATGGG AAATGGAAATCATTCACTCTGTCAAGAATTCAAAAACAAGCCAATATATCAATTGTAGAT ATAGATACTAATCAGGAGGAGAATATAGCAACTTCGTCTTCTGGAAACAACTTTGGTCTT GACTTGAAAGCAGATGACAAAATATATTTTGGTGGCCTGCCAACGCTGAGAAACTTGAGG CCAGAAGTAAATCTGAAGAAATATTCCGGCTGCCTCAAAGATATTGAAATTTCAAGAACT CCGTACAATATACTCAGTAGTCCCGATTATGTTGGTGTTACCAAAGGATGTTCCCTGGAG AATGTTTACACAGTTAGCTTTCCTAAGCCTGGTTTTGTGGAGCTCTCCCCTGTGCCAATT GATGTAGGAACAGAAATCAACCTGTCATTCAGCACCAAGAATGAGTCCGGCATCATTCTT TTGGGAAGTGGAGGGACACCAGCACCACCTAGGAGAAAACGAAGGCAGACTGGACAGGCC TATTATGTAATACTCCTCAACAGGGGCCGTCTGGAAGTGCATCTCTCCACAGGGGCACGA ACAATGAGGAAAATTGTGATCAGACCAGAGCCGAATCTGTTTCATGATGGAAGAGAACAT TCCGTTCATGTAGAGCGAACTAGAGGCATCTTTACAGTTCAAGTGGATGAAAACAGAAGA TACATGCAAAACCTGACAGTTGAACAGCCTATCGAAGTTAAAAAGCTTTTCGTTGGGGGT GCTCCACCTGAATTTCAACCTTCCCCACTCAGAAATATTCCTCCTTTTGAAGGCTGCATA TGGAATCTTGTTATTAACTCTGTCCCCATGGACTTTGCAAGGCCTGTGTCCTTCAAAAAT GCTGACATTGGTCGCTGTGCCCATCAGAAACTCCGTGAAGATGAAGATGGAGCAGCTCCA GCTGAAATAGTTATCCAGCCTGAGCCAGTTCCCACCCCAGCCTTTCCTACGCCCACCCCA GTTCTGACACATGGTCCTTGTGCTGCAGAATCAGAACCAGCTCTTTTGATAGGGAGCAAG CAGTTCGGGCTTTCAAGAAACAGTCACATTGCAATTGCATTTGATGACACCAAAGTTAAA AACCGTCTCACAATTGAGTTGGAAGTAAGAACCGAAGCTGAATCCGGCTTGCTTTTTTAC ATGGCTCGCATCAATCATGCTGATTTTGCAACAGTTCAGCTGAGAAATGGATTGCCCTAC TTCAGCTATGACTTGGGGAGTGGGGACACCCACACCATGATCCCCACCAAAATCAATGAT GGCCAGTGGCACAAGATTAAGATAATGAGAAGTAAGCAAGAAGGAATTCTTTATGTAGAT GGGGCTTCCAACAGAACCATCAGTCCCAAAAAAGCCGACATCCTGGATGTCGTGGGAATG CTGTATGTTGGTGGGTTACCCATCAACTACACTACCCGAAGAATTGGTCCAGTGACCTAT AGCATTGATGGCTGCGTCAGGAATCTCCACATGGCAGAGGCCCCTGCCGATCTGGAACAA CCCACCTCCAGCTTCCATGTTGGGACATGTTTTGCAAATGCTCAGAGGGGAACATATTTT GACGGAACCGGTTTTGCCAAAGCAGTTGGTGGATTCAAAGTGGGATTGGACCTTCTTGTA GAATTTGAATTCCGCACAACTACAACGACTGGAGTTCTTCTGGGGATCAGTAGTCAAAAA ATGGATGGAATGGGTATTGAAATGATTGATGAAAAGTTGATGTTTCATGTGGACAATGGT GCGGGCAGATTCACTGCTGTCTATGATGCTGGGGTTCCAGGGCATTTGTGTGATGGACAA TGGCATAAAGTCACTGCCAACAAGATCAAACACCGCATTGAGCTCACAGTCGATGGGAAC CAGGTGGAAGCCCAAAGCCCAAACCCAGCATCTACATCAGCTGACACAAATGACCCTGTG TTTGTTGGAGGCTTCCCAGATGACCTCAAGCAGTTTGGCCTAACAACCAGTATTCCGTTC CGAGGTTGCATCAGATCCCTGAAGCTCACCAAAGGCACAGGCAAGCCACTGGAGGTTAAT TTTGCCAAGGCCCTGGAACTGAGGGGCGTTCAACCTGTATCATGCCCAGCCAAC |
| Restriction Sites | Please inquire |
| ACCN | NM_001079823 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001079823.1, NP_001073291.1 |
| RefSeq Size | 9696 bp |
| RefSeq ORF | 9357 bp |
| Locus ID | 3908 |
| UniProt ID | P24043 |
| Protein Families | Druggable Genome |
| Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Pathways in cancer, Small cell lung cancer, Viral myocarditis |
| Gene Summary | Laminin, an extracellular protein, is a major component of the basement membrane. It is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. |
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