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PAICS (NM_001079524) Human Untagged Clone
CAT＃: SC323928
PAICS (untagged)-Human phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS), transcript variant 3
CNY 3,656.00
CNY 7,220.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ADE2; ADE2H1; AIRC; PAIS |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_001079524.1
GAAAGCTGTATTTGCTGCACGTGGAAATCTCCGTTATTTTCCAGCACCCAACAGTAGCGT
AATGGGAGTAACGGACTTAACCTCATTTCTCTTTCAGAGCATTTAGCCTTCATATGCCCT TCCCTGCATGCTTCCCCCAGGCCGTCAAGACTTGAGTTCTGCCTCGCTTCCCGGCGCGGT CGCAGCCCTCAGCCCACTTAGGATAATGGCGACAGCTGAGGTACTGAACATTGGTAAAAA ATTATATGAGGGTAAAACAAAAGAAGTCTACGAATTGTTAGACAGTCCAGGAAAAGTCCT CCTGCAGTCCAAGGACCAGATTACAGCAGGAAATGCAGCTAGAAAAAACCACCTGGAAGG AAAAGCTGCAATCTCAAATAAAATCACCAGTTGTATTTTTCAGTTATTACAGGAAGCAGG TATTAAAACTGCCTTCACCAGAAAATGTGGGGAGACAGCTTTCATTGCACCGCAGTGTGA AATGATTCCAATTGAATGGGTTTGCAGAAGAATAGCAACTGGTTCTTTTCTCAAAAGAAA TCCTGGTGTCAAGGAAGGATATAAGTTTTACCCACCTAAAGTGGAGTTGTTTTTCAAGGA TGATGCCAATAATGACCCACAGTGGTCTGAGGAACAGCTGATTGCTGCAAAATTTTGCTT TGCTGGACTTCTTATAGGCCAGACTGAAGTGGATATCATGAGTCATGCTACACAGGCTAT ATTTGAAATACTGGAGAAATCCTGGTTGCCCCAGAATTGTACACTGGTTGATATGAAGAT TGAATTTGGTGTTGATGTAACCACCAAAGAAATTGTTCTTGCTGATGTTATTGACAATGA TTCCTGGAGACTCTGGCCATCAGGAGATCGAAGCCAACAGAAAGACAAACAGTCTTATCG GGACCTCAAAGAAGTAACTCCTGAAGGGCTCCAAATGGTAAAGAAAAACTTTGAGTGGGT TGCAGAGAGAGTAGAGTTGCTTTTGAAATCAGAAAGTCAGTGCAGGGTTGTAGTGTTGAT GGGCTCTACTTCTGATCTTGGTCACTGTGAAAAAATCAAGAAGGCCTGTGGAAATTTTGG CATTCCATGTGAACTTCGAGTAACATCTGCGCATAAAGGACCAGATGAAACTCTGAGGAT TAAAGCTGAGTATGAAGGGGATGGCATTCCTACTGTATTTGTGGCAGTGGCAGGCAGAAG TAATGGTTTGGGACCAGTGATGTCTGGGAACACTGCATATCCAGTTATCAGCTGTCCTCC CCTCACACCAGACTGGGGAGTTCAGGATGTGTGGTCTTCTCTTCGACTACCCAGTGGTCT TGGCTGTTCAACCGTACTTTCTCCAGAAGGATCAGCTCAATTTGCTGCTCAGATATTTGG GTTAAGCAACCATTTGGTATGGAGCAAACTGCGAGCAAGCATTTTGAACACATGGATTTC CTTGAAGCAGGCTGACAAGAAAATCAGAGAATGTAATTTATAAGAAAGAATGCCATTGAA TTTTTTAGGGGAAAAACTACAAATTTCTAATTTAGCTGAAGGAAAATCAAGCAAGATGAA AAGGTAATTTTAAATTAGAGAACACAAATAAAATGTATTAGTGAATAAATGCTTCTCTAG ATCCATATTAATAAACATGAGCATCTAACCCCTCCTTTCTTAGGCTAGACACCAAGATAT TTCAGCCAGCCTTTATCATTCCTCTTACTTTATCCTTTTTCCTTAAGTATTGGTGGTCAC TACTATTGAGTTTCTTCCTTAACACTGATTAAATGATCTTAACTCCCTCAGCTAAAACTG GCATTACTGACTCCCAGCTATATTTCTCCAGACTTGCATTTTTTTTTTTTTTTTTGAGAC AGGGTCTCACTGTCGCCCAGGCTGGAGTGCAGTGGCGTGATCTCAGTTCACTGCTGCTTT CCCTCCTGGGCTCAAGCAGTTCTCCCACCTCAGCCTCTCGACTAACAGGGACTATAATCT TGCAGCACCATGCCGAGCTAATTTTATTTTTTGTAGAGATGAGCTCTCACTATGTCACCC AGGTTCGTCTCAAACTCCTGAACCCTAGTAATTCTCCTATCTCAGCCTCCCAAAGTGCTA GGGTTACAGACATGAGCCACTGTGCCTGTCTAGACTTGTACTTTCAACTGTCCATTTCTC CCTGTCTGTCCCATGGGCACTCATGAAAAAACAGAATGCTCCCAACTTTATTCATCTTCC AAGCCTGTAGCTCTTGGTATACTCACTGTTGCAAGTCAGAAGCTTGATTTCATCATTGAT GTTTTTCTCACGTTTCACATCTCACTCATCACCAAGTCATGTTGGTGTTAATTTCTGATT AACCCTTGAATTTACCGTCTTCTCATCCTCTGTACAAAAGCCTCAAGTGAGGGTCAAATT CAACATTATCCTGATCTAGACAGCCCCCATTCTCAATCCACCCTTTTCCAAGTTGATTGC CCAAGGACTTCTAACAATAAACTCTCTTTTGCACCACAGACTTCTTTGAAAATATACATG CTGTTGACCCTCTCTGTAGAAAACCGCACACATAAAACTTACCAACAGATTTCATTGGTT CTTGGGTTCTCCCGAAGCCTATCCATGGTTTATAGATTAAGAATTGATGAGGTAGCTGGG CACAGTGGCTCACACCTACGATCACAGCACTTCGGGAGGCTGAAGCAAGCAGATCACTTG AGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGGTGAAACCCTGTCTCTACTAAAAATA CAAAAAGTAGCCAGCCGTGATGACAGGCACCTGTAATCCCAGCTACTCGGGAGGCTGAGG CATGAGAATTGCTTGAACCCGGGAGGCGGAGGTTGCAGTGAGCCTGGATCATGCCACTGC ACTCCAACCTGGGCAGCAGAGCAAGACTCTGTCTCAAAAGGGGAAAAAAAAAATTGCTGA TGTGACCCATGAAGGGAACTCATTTTCCTCGTAATTTTGGACTGCCACACATTGGTACCT TTAGTTCTCTGAAGGCCCACGTTTTTATCATTAAGACCTATTTGTTAGCTAGTAGAGCTT TATGTTCGCTGTCCATGAAACCTTCTGTAACCACAGTGACTACAAGTAGTTCTTTCTCTA TTGAATTATTAGGTCCAGAATAGAAGATGTCATTGTACACTTTATTTCCCTCACACTGTG TTATGCTCTGATGTGCTATGCTTAGCTATCTGTCAGAGATTAGTAAATTATAAAACTCAT GTGTACTACTTAAGTTTATATCTTATGCTAGTTTATAAGAACAATTAAAAGGACTTAGAA GATTAAAAAAAAAAAAAAAAAA |
| Restriction Sites | ECoRI-NOT |
| ACCN | NM_001079524 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001079524.1, NP_001072992.1 |
| RefSeq Size | 3329 bp |
| RefSeq ORF | 1278 bp |
| Locus ID | 10606 |
| UniProt ID | P22234 |
| Protein Families | Druggable Genome |
| Protein Pathways | Metabolic pathways, Purine metabolism |
| Gene Summary | This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (3) lacks an alternate in-frame exon in the CDS, compared to variant 1, resulting in a shorter protein (isoform 2), compared to isoform 1. Variants 2 and 3 encode the same isoform. |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201530 | PAICS (Myc-DDK-tagged)-Human phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS), transcript variant 3 |
CNY 3,656.00 |
|
| RC201530L3 | Lenti ORF clone of Human phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS), transcript variant 3, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC201530L4 | Lenti ORF clone of Human phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS), transcript variant 3, mGFP tagged |
CNY 5,890.00 |
|
| RG201530 | PAICS (tGFP-tagged) - Human phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS), transcript variant 3 |
CNY 4,370.00 |
