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VAV3 (NM_006113) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC220550L4V
- LentiORF®
-
Lenti ORF particles, VAV3 (mGFP-tagged) - Human vav 3 guanine nucleotide exchange factor (VAV3), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 17,100.00
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Specifications
| Product Data | |
| Product Name | VAV3 (NM_006113) Human Tagged ORF Clone Lentiviral Particle |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_006113 |
| ORF Size | 2541 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC220550).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_006113.3 |
| RefSeq Size | 4768 bp |
| RefSeq ORF | 2544 bp |
| Locus ID | 10451 |
| Domains | RhoGEF, SH2, SH3, CH, PH, DAG_PE-bind |
| Protein Families | Druggable Genome |
| Protein Pathways | B cell receptor signaling pathway, Chemokine signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, Leukocyte transendothelial migration, Natural killer cell mediated cytotoxicity, Regulation of actin cytoskeleton, T cell receptor signaling pathway |
| MW | 97.6 kDa |
| Gene Summary | This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] |
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