GNG5 (NM_005274) Human Mass Spec Standard

Specifications

Product Data
Description	GNG5 MS Standard C13 and N15-labeled recombinant protein (NP_005265)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC200572
Predicted MW	7.3 kDa
Protein Sequence	Sequence Link (showhide) >RC200572 protein sequence Red=Cloning site Green=Tags(s) MSGSSSVAAMKKVVQQLRLEAGLNRVKVSQAAADLKQFCLQNAQHDPLLTGVSSSTNPFRPQKVCSFL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_005265
RefSeq Size	823
RefSeq ORF	204
Locus ID	2787
Cytogenetics	1p22.3
Summary	G proteins are trimeric (alpha-beta-gamma) membrane-associated proteins that regulate flow of information from cell surface receptors to a variety of internal metabolic effectors. Interaction of a G protein with its activated receptor promotes exchange of GTP for GDP that is bound to the alpha subunit. The alpha-GTP complex dissociates from the beta-gamma heterodimer so that the subunits, in turn, may interact with and regulate effector molecules (Gilman, 1987 [PubMed 3113327]; summary by Ahmad et al., 1995) [PubMed 7606925].[supplied by OMIM, Nov 2010]
Protein Pathways	Chemokine signaling pathway

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