Cytochrome b5 (CYB5A) (NM_148923) Human Mass Spec Standard

Specifications

Product Data
Description	CYB5A MS Standard C13 and N15-labeled recombinant protein (NP_683725)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC202378
Predicted MW	15.3 kDa
Protein Sequence	Sequence Link (showhide) >RC202378 protein sequence Red=Cloning site Green=Tags(s) MAEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENFEDVGHST DAREMSKTFIIGELHPDDRPKLNKPPETLITTIDSSSSWWTNWVIPAISAVAVALMYRLYMAED TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_683725
RefSeq Size	850
RefSeq ORF	402
Synonyms	CYB5; MCB5; METAG
Locus ID	1528
Cytogenetics	18q22.3
Summary	The protein encoded by this gene is a membrane-bound cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. Defects in this gene are a cause of type IV hereditary methemoglobinemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
Protein Families	Transmembrane

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