CDC45L (CDC45) (NM_003504) Human Mass Spec Standard

CAT#: PH302442

CDC45 MS Standard C13 and N15-labeled recombinant protein (NP_003495)



  View other "CDC45L" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of CDC45 cell division cycle 45-like (S. cerevisiae) (CDC45L)
    • 100 ug

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CDC45 mouse monoclonal antibody,clone OTI4F3
    • 100 ul

CNY 1,999.00
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Specifications

Product Data
Description CDC45 MS Standard C13 and N15-labeled recombinant protein (NP_003495)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC202442
Predicted MW 65.6 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_003495
RefSeq Size 1998
RefSeq ORF 1698
Synonyms CDC45L; CDC45L2; MGORS7; PORC-PI-1
Locus ID 8318
Cytogenetics 22q11.21
Summary The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways Cell cycle
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