Rab4 (RAB4A) (NM_004578) Human Mass Spec Standard

Specifications

Product Data
Description	RAB4A MS Standard C13 and N15-labeled recombinant protein (NP_004569)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC202572
Predicted MW	24.4 kDa
Protein Sequence	Sequence Link (showhide) >RC202572 protein sequence Red=Cloning site Green=Tags(s) MSQTAMSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVGGKYVKLQIWDTA GQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCGNKKDLDADREVTFLE ASRFAQENELMFLETSALTGENVEEAFVQCARKILNKIESGELDPERMGSGIQYGDAALRQLRSPRRAQA PNAQECGC TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_004569
RefSeq Size	3056
RefSeq ORF	654
Synonyms	HRES-1; HRES-1/RAB4; HRES1; RAB4
Locus ID	5867
Cytogenetics	1q42.13
Summary	This gene is a member of the largest group in the Ras superfamily of small GTPases, which regulate membrane trafficking. The encoded protein is associated with early endosomes and is involved in their sorting and recycling. The protein also plays a role in regulating the recycling of receptors from endosomes to the plasma membrane. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012]
Protein Families	Druggable Genome
Protein Pathways	Endocytosis

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