CAMKK2 (NM_172226) Human Mass Spec Standard

CAT#: PH303468

CAMKK2 MS Standard C13 and N15-labeled recombinant protein (NP_757380)



  View other "CAMKK2" proteins (13)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Rabbit Polyclonal Anti-CAMKK2 Antibody
    • 50 ug

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Transient overexpression lysate of calcium/calmodulin-dependent protein kinase kinase 2, beta (CAMKK2), transcript variant 2
    • 100 ug

CNY 4,840.00

Specifications

Product Data
Description CAMKK2 MS Standard C13 and N15-labeled recombinant protein (NP_757380)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC203468
Predicted MW 59.6 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_757380
RefSeq Size 4923
RefSeq ORF 1623
Synonyms CAMKK; CAMKKB
Locus ID 10645
Cytogenetics 12q24.31
Summary The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases. [provided by RefSeq, Jul 2012]
Protein Families Druggable Genome, Protein Kinase, Transcription Factors
Protein Pathways Adipocytokine signaling pathway
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