NDUFS6 (NM_004553) Human Mass Spec Standard

Specifications

Product Data
Description	NDUFS6 MS Standard C13 and N15-labeled recombinant protein (NP_004544)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC207108
Predicted MW	13.7 kDa
Protein Sequence	Sequence Link (showhide) >RC207108 protein sequence Red=Cloning site Green=Tags(s) MAAAMTFCRLLNRCGEAARSLPLGARCFGVRVSPTGEKVTHTGQVYDDKDYRRIRFVGRQKEVNENFAID LIAEQPVSEVETRVIACDGGGGALGHPKVYINLDKETKTGTCGYCGLQFRQHHH TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_004544
RefSeq Size	554
RefSeq ORF	372
Synonyms	CI-13kA; CI-13kD-A; CI13KDA; MC1DN9
Locus ID	4726
Cytogenetics	5p15.33
Summary	This gene encodes a subunit of the NADH:ubiquinone oxidoreductase (complex I), which is the first enzyme complex in the electron transport chain of mitochondria. This complex functions in the transfer of electrons from NADH to the respiratory chain. The subunit encoded by this gene is one of seven subunits in the iron-sulfur protein fraction. Mutations in this gene cause mitochondrial complex I deficiency, a disease that causes a wide variety of clinical disorders, including neonatal disease and adult-onset neurodegenerative disorders.[provided by RefSeq, Oct 2009]
Protein Pathways	Alzheimer's disease, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease

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