GNMT (NM_018960) Human Mass Spec Standard

CAT#: PH307497

GNMT MS Standard C13 and N15-labeled recombinant protein (NP_061833)



  View other "GNMT" proteins (4)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description GNMT MS Standard C13 and N15-labeled recombinant protein (NP_061833)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC207497
Predicted MW 32.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_061833
RefSeq Size 1091
RefSeq ORF 885
Synonyms HEL-S-182mP
Locus ID 27232
Cytogenetics 6p21.1
Summary The protein encoded by this gene is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine (along with glycine) to S-adenosyl-L-homocysteine and sarcosine. This protein is found in the cytoplasm and acts as a homotetramer. Defects in this gene are a cause of GNMT deficiency (hypermethioninemia). Alternative splicing results in multiple transcript variants. Naturally occurring readthrough transcription occurs between the upstream CNPY3 (canopy FGF signaling regulator 3) gene and this gene and is represented with GeneID:107080644. [provided by RefSeq, Jan 2016]
Protein Families Druggable Genome
Protein Pathways Glycine, serine and threonine metabolism
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