TRP1 (TYRP1) (NM_000550) Human Mass Spec Standard

Specifications

Product Data
Description	TYRP1 MS Standard C13 and N15-labeled recombinant protein (NP_000541)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC208595
Predicted MW	60.7 kDa
Protein Sequence	Sequence Link (showhide) >RC208595 protein sequence Red=Cloning site Green=Tags(s) MSAPKLLSLGCIFFPLLLFQQARAQFPRQCATVEALRSGMCCPDLSPVSGPGTDRCGSSSGRGRCEAVTA DSRPHSPQYPHDGRDDREVWPLRFFNRTCHCNGNFSGHNCGTCRPGWRGAACDQRVLIVRRNLLDLSKEE KNHFVRALDMAKRTTHPLFVIATRRSEEILGPDGNTPQFENISIYNYFVWTHYYSVKKTFLGVGQESFGE VDFSHEGPAFLTWHRYHLLRLEKDMQEMLQEPSFSLPYWNFATGKNVCDICTDDLMGSRSNFDSTLISPN SVFSQWRVVCDSLEDYDTLGTLCNSTEDGPIRRNPAGNVARPMVQRLPEPQDVAQCLEVGLFDTPPFYSN STNSFRNTVEGYSDPTGKYDPAVRSLHNLAHLFLNGTGGQTHLSPNDPIFVLLHTFTDAVFDEWLRRYNA DISTFPLENAPIGHNRQYNMVPFWPPVTNTEMFVTAPDNLGYTYEIQWPSREFSVPEIIAIAVVGALLLV ALIFGTASYLIRARRSMDEANQPLLTDQYQCYAEEYEKLQNPNQSVV TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_000541
RefSeq Size	2876
RefSeq ORF	1611
Synonyms	b-PROTEIN; CAS2; CATB; GP75; OCA3; TRP; TRP1; TYRP
Locus ID	7306
Cytogenetics	9p23
Summary	This gene encodes a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Defects in this gene are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III. [provided by RefSeq, Mar 2009]
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Melanogenesis, Metabolic pathways, Tyrosine metabolism

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