Hairless (HR) (NM_005144) Human Mass Spec Standard

CAT#: PH309010

HR MS Standard C13 and N15-labeled recombinant protein (NP_005135)



  View other "Hairless" proteins (7)

Need it in bulk or customized?
Get a free quote

CNY 14,250.00


货期*
5周

规格
    • 10 ug

Product images

经常一起买 (2)
Transient overexpression lysate of hairless homolog (mouse) (HR), transcript variant 1
    • 100 ug

CNY 3,080.00


HR mouse monoclonal antibody, clone OTI1D9 (formerly 1D9)
    • 100 ul

CNY 1,999.00
CNY 2,700.00

Specifications

Product Data
Description HR MS Standard C13 and N15-labeled recombinant protein (NP_005135)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC209010
Predicted MW 127.5 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_005135
RefSeq Size 5528
RefSeq ORF 3567
Synonyms ALUNC; AU; HSA277165; HYPT4; MUHH; MUHH1
Locus ID 55806
Cytogenetics 8p21.3
Summary This gene encodes a protein that is involved in hair growth. This protein functions as a transcriptional corepressor of multiple nuclear receptors, including thyroid hormone receptor, the retinoic acid receptor-related orphan receptors and the vitamin D receptors, and it interacts with histone deacetylases. The translation of this protein is modulated by a regulatory open reading frame (ORF) that exists upstream of the primary ORF. Mutations in this upstream ORF cause Marie Unna hereditary hypotrichosis (MUHH), an autosomal dominant form of genetic hair loss. Mutations in this gene also cause autosomal recessive congenital alopecia and atrichia with papular lesions, other diseases resulting in hair loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2014]
Protein Families Druggable Genome, Transcription Factors
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Documents

Other Versions

Customer Reviews 
Loading...