COMMD5 (NM_014066) Human Mass Spec Standard

CAT#: PH309381

COMMD5 MS Standard C13 and N15-labeled recombinant protein (NP_054785)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description COMMD5 MS Standard C13 and N15-labeled recombinant protein (NP_054785)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC209381
Predicted MW 24.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_054785
RefSeq Size 1475
RefSeq ORF 672
Synonyms HCARG; HT002
Locus ID 28991
Cytogenetics 8q24.3
Summary May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis (By similarity). Down-regulates activation of NF-kappa-B (PubMed:15799966).[UniProtKB/Swiss-Prot Function]
Protein Families Druggable Genome
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