IRF3 (NM_001571) Human Mass Spec Standard

CAT#: PH309951

IRF3 MS Standard C13 and N15-labeled recombinant protein (NP_001562)



  View other "IRF3" proteins (8)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description IRF3 MS Standard C13 and N15-labeled recombinant protein (NP_001562)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC209951
Predicted MW 47.2 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001562
RefSeq Size 1626
RefSeq ORF 1281
Synonyms IIAE7
Locus ID 3661
Cytogenetics 19q13.33
Summary This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses. Mutations in this gene are associated with Encephalopathy, acute, infection-induced, herpes-specific, 7. [provided by RefSeq, Sep 2020]
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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