MMP3 (NM_002422) Human Mass Spec Standard

CAT#: PH310235

MMP3 MS Standard C13 and N15-labeled recombinant protein (NP_002413)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description MMP3 MS Standard C13 and N15-labeled recombinant protein (NP_002413)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC210235
Predicted MW 54 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_002413
RefSeq Size 1828
RefSeq ORF 1431
Synonyms CHDS6; MMP-3; SL-1; STMY; STMY1; STR1
Locus ID 4314
Cytogenetics 11q22.2
Summary Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Protease
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